head and neck neoplasms; neoplasm recurrence, local; neoplasms, second primary Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description disease cluster belonging to disease group cancer (Genetic Association Database)
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Genes

140 genes associated with the disease head and neck neoplasms; neoplasm recurrence, local; neoplasms, second primary in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ACVR1B activin A receptor, type IB
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
ADH6 alcohol dehydrogenase 6 (class V)
AGO1 argonaute RISC catalytic component 1
ALDH18A1 aldehyde dehydrogenase 18 family, member A1
ANGPT4 angiopoietin 4
ANGPTL1 angiopoietin-like 1
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ATG4A autophagy related 4A, cysteine peptidase
ATG9A autophagy related 9A
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
ATP5L ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
AURKA aurora kinase A
BAG1 BCL2-associated athanogene
BAG3 BCL2-associated athanogene 3
BAG5 BCL2-associated athanogene 5
BAX BCL2-associated X protein
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCL2L2 BCL2-like 2
BIRC5 baculoviral IAP repeat containing 5
BIRC6 baculoviral IAP repeat containing 6
BMF Bcl2 modifying factor
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CA9 carbonic anhydrase IX
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CD34 CD34 molecule
CD4 CD4 molecule
CD44 CD44 molecule (Indian blood group)
CDC7 cell division cycle 7
CDK4 cyclin-dependent kinase 4
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
COL18A1 collagen, type XVIII, alpha 1
COX18 COX18 cytochrome c oxidase assembly factor
DDB2 damage-specific DNA binding protein 2, 48kDa
DDX20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20
DGCR8 DGCR8 microprocessor complex subunit
DICER1 dicer 1, ribonuclease type III
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DROSHA drosha, ribonuclease type III
E2F2 E2F transcription factor 2
E2F7 E2F transcription factor 7
EMC8 ER membrane protein complex subunit 8
EPHX2 epoxide hydrolase 2, cytoplasmic
ERN1 endoplasmic reticulum to nucleus signaling 1
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit
FANCD2 Fanconi anemia, complementation group D2
FAS Fas cell surface death receptor
FEN1 flap structure-specific endonuclease 1
FGF2 fibroblast growth factor 2 (basic)
FGF5 fibroblast growth factor 5
FGF9 fibroblast growth factor 9
FOXO1 forkhead box O1
FZD3 frizzled class receptor 3
FZD4 frizzled class receptor 4
GEMIN4 gem (nuclear organelle) associated protein 4
GHITM growth hormone inducible transmembrane protein
GHRHR growth hormone releasing hormone receptor
GPER1 G protein-coupled estrogen receptor 1
GPX7 glutathione peroxidase 7
GSTM3 glutathione S-transferase mu 3 (brain)
GSTM5 glutathione S-transferase mu 5
HSPB8 heat shock 22kDa protein 8
ICAM1 intercellular adhesion molecule 1
IGF2-AS IGF2 antisense RNA
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP5 insulin-like growth factor binding protein 5
IL1R1 interleukin 1 receptor, type I
KMT2A lysine (K)-specific methyltransferase 2A
KRAS Kirsten rat sarcoma viral oncogene homolog
MBD1 methyl-CpG binding domain protein 1
MDM4 MDM4, p53 regulator
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa
NEIL2 nei endonuclease VIII-like 2 (E. coli)
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NODAL nodal growth differentiation factor
NOTCH1 notch 1
NQO1 NAD(P)H dehydrogenase, quinone 1
NR1I2 nuclear receptor subfamily 1, group I, member 2
OGG1 8-oxoguanine DNA glycosylase
PDGFC platelet derived growth factor C
PGRMC2 progesterone receptor membrane component 2
PLK1 polo-like kinase 1
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
POLH polymerase (DNA directed), eta
PON1 paraoxonase 1
RAD51D RAD51 paralog D
RAN RAN, member RAS oncogene family
RET ret proto-oncogene
RICTOR RPTOR independent companion of MTOR, complex 2
RING1 ring finger protein 1
RPA1 replication protein A1, 70kDa
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
RRM1 ribonucleotide reductase M1
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
RXRA retinoid X receptor, alpha
SETD1A SET domain containing 1A
SIRT3 sirtuin 3
SMAD1 SMAD family member 1
SMAD3 SMAD family member 3
SMAD7 SMAD family member 7
SMC1B structural maintenance of chromosomes 1B
SMO smoothened, frizzled class receptor
SNAI1 snail family zinc finger 1
SP1 Sp1 transcription factor
SPP1 secreted phosphoprotein 1
SST somatostatin
SSTR1 somatostatin receptor 1
SSTR2 somatostatin receptor 2
SUFU suppressor of fused homolog (Drosophila)
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
SULT4A1 sulfotransferase family 4A, member 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TSC1 tuberous sclerosis 1
TXN2 thioredoxin 2
UGT2A3 UDP glucuronosyltransferase 2 family, polypeptide A3
UGT3A2 UDP glycosyltransferase 3 family, polypeptide A2
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
WNT11 wingless-type MMTV integration site family, member 11
WNT2B wingless-type MMTV integration site family, member 2B
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XPO5 exportin 5
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)