head and neck cancer Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description An organ system cancer that arises in the head or neck region. This region includes the nasal cavity, sinuses, lips, mouth, salivary glands, throat, or larynx. (Human Disease Ontology, DOID_11934)
Similar Terms
Downloads & Tools

Genes

71 genes associated with the disease head and neck cancer in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
AR androgen receptor
AXIN2 axin 2
BRCA2 breast cancer 2, early onset
CAT catalase
CCND1 cyclin D1
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CDK6 cyclin-dependent kinase 6
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
CXCL12 chemokine (C-X-C motif) ligand 12
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
EGFR epidermal growth factor receptor
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ERCC1 excision repair cross-complementation group 1
ERCC2 excision repair cross-complementation group 2
FGFR4 fibroblast growth factor receptor 4
GLI2 GLI family zinc finger 2
GPX1 glutathione peroxidase 1
GSTM1 glutathione S-transferase mu 1
GSTM3 glutathione S-transferase mu 3 (brain)
GSTM4 glutathione S-transferase mu 4
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
IGF1R insulin-like growth factor 1 receptor
KRAS Kirsten rat sarcoma viral oncogene homolog
MET MET proto-oncogene, receptor tyrosine kinase
MGMT O-6-methylguanine-DNA methyltransferase
MKI67 marker of proliferation Ki-67
MMP1 matrix metallopeptidase 1
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MNAT1 MNAT CDK-activating kinase assembly factor 1
MRC2 mannose receptor, C type 2
MUTYH mutY homolog
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NHEJ1 nonhomologous end-joining factor 1
PDGFB platelet-derived growth factor beta polypeptide
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PROM1 prominin 1
RAD51 RAD51 recombinase
RAD52 RAD52 homolog (S. cerevisiae)
RECQL4 RecQ protein-like 4
RNF2 ring finger protein 2
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
TIMP2 TIMP metallopeptidase inhibitor 2
TNF tumor necrosis factor
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TP53 tumor protein p53
TP73 tumor protein p73
TYMS thymidylate synthetase
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7
VEGFA vascular endothelial growth factor A
XPC xeroderma pigmentosum, complementation group C
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6