harmine-7209 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the harmine-7209 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTA2 actin, alpha 2, smooth muscle, aorta
AK2 adenylate kinase 2
ANKRD10 ankyrin repeat domain 10
AOC2 amine oxidase, copper containing 2 (retina-specific)
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APOD apolipoprotein D
APOLD1 apolipoprotein L domain containing 1
ATF3 activating transcription factor 3
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1
BTBD7 BTB (POZ) domain containing 7
BTF3P11 basic transcription factor 3 pseudogene 11
BTG2 BTG family, member 2
C11ORF63 chromosome 11 open reading frame 63
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CD79B CD79b molecule, immunoglobulin-associated beta
CD8B CD8b molecule
CDKL3 cyclin-dependent kinase-like 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CES1 carboxylesterase 1
CES2 carboxylesterase 2
CLCN7 chloride channel, voltage-sensitive 7
CREM cAMP responsive element modulator
DIEXF digestive organ expansion factor homolog (zebrafish)
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DST dystonin
ERN2 endoplasmic reticulum to nucleus signaling 2
EXO5 exonuclease 5
FAS Fas cell surface death receptor
FOLR1 folate receptor 1 (adult)
FOSL1 FOS-like antigen 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GPR68 G protein-coupled receptor 68
GPR87 G protein-coupled receptor 87
GREB1 growth regulation by estrogen in breast cancer 1
HBS1L HBS1-like translational GTPase
HIST1H3B histone cluster 1, H3b
HIST1H3H histone cluster 1, H3h
HLA-DMA major histocompatibility complex, class II, DM alpha
HNF1B HNF1 homeobox B
IDI2-AS1 IDI2 antisense RNA 1
KIAA0319L KIAA0319-like
LIF leukemia inhibitory factor
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LOC157562 uncharacterized LOC157562
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED6 mediator complex subunit 6
METTL7A methyltransferase like 7A
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
N4BP2L1 NEDD4 binding protein 2-like 1
N4BP2L2 NEDD4 binding protein 2-like 2
NEK9 NIMA-related kinase 9
NGDN neuroguidin, EIF4E binding protein
NHLH2 nescient helix loop helix 2
NLE1 notchless homolog 1 (Drosophila)
NOL12 nucleolar protein 12
NPR3 natriuretic peptide receptor 3
OVGP1 oviductal glycoprotein 1, 120kDa
PAPOLA poly(A) polymerase alpha
PHLDB1 pleckstrin homology-like domain, family B, member 1
PIDD1 p53-induced death domain protein 1
PILRA paired immunoglobin-like type 2 receptor alpha
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
POU1F1 POU class 1 homeobox 1
PSG9 pregnancy specific beta-1-glycoprotein 9
PVT1 Pvt1 oncogene (non-protein coding)
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RERE arginine-glutamic acid dipeptide (RE) repeats
RPL31 ribosomal protein L31
RSL1D1 ribosomal L1 domain containing 1
RUNX1 runt-related transcription factor 1
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SESN1 sestrin 1
SMC4 structural maintenance of chromosomes 4
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SMIM7 small integral membrane protein 7
SOX9 SRY (sex determining region Y)-box 9
SPRR2B small proline-rich protein 2B
TAT tyrosine aminotransferase
TBC1D8 TBC1 domain family, member 8 (with GRAM domain)
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TRIM66 tripartite motif containing 66
TSC2 tuberous sclerosis 2
UBE2L3 ubiquitin-conjugating enzyme E2L 3
UBOX5 U-box domain containing 5
UTRN utrophin
ZBTB1 zinc finger and BTB domain containing 1
ZMAT3 zinc finger, matrin-type 3
ZNF324 zinc finger protein 324
ZNF606 zinc finger protein 606
ZNF79 zinc finger protein 79
ZNF862 zinc finger protein 862
ZNF93 zinc finger protein 93
ZRSR1 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1

decreased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
ACVR1 activin A receptor, type I
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARMCX5 armadillo repeat containing, X-linked 5
BAG2 BCL2-associated athanogene 2
BET1 Bet1 golgi vesicular membrane trafficking protein
BRWD1 bromodomain and WD repeat domain containing 1
C12ORF4 chromosome 12 open reading frame 4
C9ORF91 chromosome 9 open reading frame 91
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CBR4 carbonyl reductase 4
CCNE2 cyclin E2
CDC37L1 cell division cycle 37-like 1
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHMP6 charged multivesicular body protein 6
CHMP7 charged multivesicular body protein 7
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
CTPS1 CTP synthase 1
DEAF1 DEAF1 transcription factor
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
EFHD2 EF-hand domain family, member D2
EFNA4 ephrin-A4
EXOC2 exocyst complex component 2
FA2H fatty acid 2-hydroxylase
FAM188A family with sequence similarity 188, member A
FAM63A family with sequence similarity 63, member A
FAN1 FANCD2/FANCI-associated nuclease 1
FANCL Fanconi anemia, complementation group L
FOXD1 forkhead box D1
FOXK2 forkhead box K2
GLMN glomulin, FKBP associated protein
GPRC5C G protein-coupled receptor, class C, group 5, member C
GTF2IRD1 GTF2I repeat domain containing 1
H1F0 H1 histone family, member 0
HSPA2 heat shock 70kDa protein 2
ICK intestinal cell (MAK-like) kinase
IRX4 iroquois homeobox 4
KIAA0020 KIAA0020
KIAA0513 KIAA0513
KIAA0922 KIAA0922
KIF3A kinesin family member 3A
KIN Kin17 DNA and RNA binding protein
KLHL36 kelch-like family member 36
LBR lamin B receptor
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
MAGOHB mago-nashi homolog B (Drosophila)
MEPCE methylphosphate capping enzyme
MKLN1 muskelin 1, intracellular mediator containing kelch motifs
MNS1 meiosis-specific nuclear structural 1
MRPS31 mitochondrial ribosomal protein S31
MSX1 msh homeobox 1
MTMR6 myotubularin related protein 6
NAA38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit
NOC3L nucleolar complex associated 3 homolog (S. cerevisiae)
NOL8 nucleolar protein 8
OFD1 oral-facial-digital syndrome 1
PAQR3 progestin and adipoQ receptor family member III
PLEKHO1 pleckstrin homology domain containing, family O member 1
POLD3 polymerase (DNA-directed), delta 3, accessory subunit
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1
RAI14 retinoic acid induced 14
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RIBC2 RIB43A domain with coiled-coils 2
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RIT1 Ras-like without CAAX 1
SCAF8 SR-related CTD-associated factor 8
SETD8 SET domain containing (lysine methyltransferase) 8
SFT2D2 SFT2 domain containing 2
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC35A5 solute carrier family 35, member A5
SLC38A10 solute carrier family 38, member 10
SMCO4 single-pass membrane protein with coiled-coil domains 4
SMNDC1 survival motor neuron domain containing 1
SNUPN snurportin 1
SNX10 sorting nexin 10
SPAST spastin
SPATA2L spermatogenesis associated 2-like
SPC25 SPC25, NDC80 kinetochore complex component
STX18 syntaxin 18
TBC1D31 TBC1 domain family, member 31
TFB1M transcription factor B1, mitochondrial
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast)
TIPIN TIMELESS interacting protein
TRIM45 tripartite motif containing 45
TRMT61B tRNA methyltransferase 61B
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
WDR44 WD repeat domain 44
WDR70 WD repeat domain 70
XPA xeroderma pigmentosum, complementation group A
ZCCHC2 zinc finger, CCHC domain containing 2
ZMYM3 zinc finger, MYM-type 3
ZNF33B zinc finger protein 33B
ZNF692 zinc finger protein 692