harmaline-4968 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the harmaline-4968 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACYP1 acylphosphatase 1, erythrocyte (common) type
ADAM22 ADAM metallopeptidase domain 22
AHI1 Abelson helper integration site 1
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
BLZF1 basic leucine zipper nuclear factor 1
C14ORF79 chromosome 14 open reading frame 79
C4BPA complement component 4 binding protein, alpha
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CD3D CD3d molecule, delta (CD3-TCR complex)
CD82 CD82 molecule
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CEP290 centrosomal protein 290kDa
CLCN6 chloride channel, voltage-sensitive 6
CLCN7 chloride channel, voltage-sensitive 7
COL5A1 collagen, type V, alpha 1
CPEB3 cytoplasmic polyadenylation element binding protein 3
CXCR4 chemokine (C-X-C motif) receptor 4
DCAF8 DDB1 and CUL4 associated factor 8
DNAI2 dynein, axonemal, intermediate chain 2
DUSP4 dual specificity phosphatase 4
EGR3 early growth response 3
EMP1 epithelial membrane protein 1
EPHX2 epoxide hydrolase 2, cytoplasmic
FGF23 fibroblast growth factor 23
GLRX3 glutaredoxin 3
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GPR153 G protein-coupled receptor 153
GSPT1 G1 to S phase transition 1
GUSBP3 glucuronidase, beta pseudogene 3
HAB1 B1 for mucin
HIRA histone cell cycle regulator
HMGN5 high mobility group nucleosome binding domain 5
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOXB2 homeobox B2
HOXB3 homeobox B3
HOXB7 homeobox B7
IL1RL1 interleukin 1 receptor-like 1
ING2 inhibitor of growth family, member 2
ING4 inhibitor of growth family, member 4
KATNB1 katanin p80 (WD repeat containing) subunit B 1
KCNK5 potassium channel, two pore domain subfamily K, member 5
KCTD17 potassium channel tetramerization domain containing 17
KPNA5 karyopherin alpha 5 (importin alpha 6)
LAT2 linker for activation of T cells family, member 2
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LMTK2 lemur tyrosine kinase 2
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP2K5 mitogen-activated protein kinase kinase 5
MGC12488
MIA3 melanoma inhibitory activity family, member 3
MINK1 misshapen-like kinase 1
MTRF1L mitochondrial translational release factor 1-like
MXD3 MAX dimerization protein 3
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NME5 NME/NM23 family member 5
NR4A1 nuclear receptor subfamily 4, group A, member 1
NUPR1 nuclear protein, transcriptional regulator, 1
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2
PAWR PRKC, apoptosis, WT1, regulator
PCNX pecanex homolog (Drosophila)
PIDD1 p53-induced death domain protein 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLA2G1B phospholipase A2, group IB (pancreas)
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
POU2F2 POU class 2 homeobox 2
PQLC2 PQ loop repeat containing 2
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTK6 protein tyrosine kinase 6
PTPRO protein tyrosine phosphatase, receptor type, O
PTRF polymerase I and transcript release factor
RAB6A RAB6A, member RAS oncogene family
RAD23B RAD23 homolog B (S. cerevisiae)
RAD51 RAD51 recombinase
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RPL35A ribosomal protein L35a
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
SCAPER S-phase cyclin A-associated protein in the ER
SOCS6 suppressor of cytokine signaling 6
SPON2 spondin 2, extracellular matrix protein
SSPN sarcospan
STON1 stonin 1
SYN2 synapsin II
TADA2A transcriptional adaptor 2A
TBX3 T-box 3
TEP1 telomerase-associated protein 1
THNSL1 threonine synthase-like 1 (S. cerevisiae)
THOC5 THO complex 5
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
UNC13A unc-13 homolog A (C. elegans)
VAV2 vav 2 guanine nucleotide exchange factor
VWA5A von Willebrand factor A domain containing 5A
ZNF230 zinc finger protein 230
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ACOT8 acyl-CoA thioesterase 8
ACTG2 actin, gamma 2, smooth muscle, enteric
ACTL8 actin-like 8
ANKZF1 ankyrin repeat and zinc finger domain containing 1
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BAHD1 bromo adjacent homology domain containing 1
BIRC3 baculoviral IAP repeat containing 3
C5AR2 complement component 5a receptor 2
CA5BP1 carbonic anhydrase VB pseudogene 1
CGA glycoprotein hormones, alpha polypeptide
CHMP7 charged multivesicular body protein 7
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CLCF1 cardiotrophin-like cytokine factor 1
CNGB3 cyclic nucleotide gated channel beta 3
CYB5R1 cytochrome b5 reductase 1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DVL1 dishevelled segment polarity protein 1
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
FAAH fatty acid amide hydrolase
FAM160B2 family with sequence similarity 160, member B2
FILIP1L filamin A interacting protein 1-like
FRMD1 FERM domain containing 1
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GATA4 GATA binding protein 4
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GTF2I general transcription factor IIi
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HAMP hepcidin antimicrobial peptide
HOXA4 homeobox A4
HOXC10 homeobox C10
HOXC5 homeobox C5
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IRF2BP1 interferon regulatory factor 2 binding protein 1
ISG15 ISG15 ubiquitin-like modifier
KDM5C lysine (K)-specific demethylase 5C
KLRG1 killer cell lectin-like receptor subfamily G, member 1
KREMEN2 kringle containing transmembrane protein 2
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
MAGEH1 melanoma antigen family H1
MATK megakaryocyte-associated tyrosine kinase
MCC mutated in colorectal cancers
MFAP2 microfibrillar-associated protein 2
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MSI1 musashi RNA-binding protein 1
MTA2 metastasis associated 1 family, member 2
PCDHB3 protocadherin beta 3
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PEX26 peroxisomal biogenesis factor 26
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PLCD1 phospholipase C, delta 1
PLD2 phospholipase D2
PODXL2 podocalyxin-like 2
POLL polymerase (DNA directed), lambda
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRICKLE3 prickle homolog 3 (Drosophila)
RAB30 RAB30, member RAS oncogene family
RAB3A RAB3A, member RAS oncogene family
RAB4B RAB4B, member RAS oncogene family
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF31 ring finger protein 31
RNF39 ring finger protein 39
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
SCGB2A2 secretoglobin, family 2A, member 2
SETD1A SET domain containing 1A
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SREBF2 sterol regulatory element binding transcription factor 2
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SYT17 synaptotagmin XVII
TARP TCR gamma alternate reading frame protein
TBC1D19 TBC1 domain family, member 19
TMEM57 transmembrane protein 57
TNRC6B trinucleotide repeat containing 6B
TPCN1 two pore segment channel 1
TRAF2 TNF receptor-associated factor 2
TRIM21 tripartite motif containing 21
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TUBA3C tubulin, alpha 3c
ULBP2 UL16 binding protein 2
USB1 U6 snRNA biogenesis 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
ZBTB44 zinc finger and BTB domain containing 44
ZCCHC24 zinc finger, CCHC domain containing 24
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF227 zinc finger protein 227
ZNF248 zinc finger protein 248
ZNF329 zinc finger protein 329