haloperidol-983 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the haloperidol-983 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM22 ADAM metallopeptidase domain 22
AHNAK2 AHNAK nucleoprotein 2
ALCAM activated leukocyte cell adhesion molecule
ALOX15 arachidonate 15-lipoxygenase
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BMP5 bone morphogenetic protein 5
BMP6 bone morphogenetic protein 6
CD22 CD22 molecule
CDK13 cyclin-dependent kinase 13
COPA coatomer protein complex, subunit alpha
CSHL1 chorionic somatomammotropin hormone-like 1
CTSK cathepsin K
DSPP dentin sialophosphoprotein
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
EPS8L1 EPS8-like 1
F11R F11 receptor
FSCN1 fascin actin-bundling protein 1
G3BP2 GTPase activating protein (SH3 domain) binding protein 2
GPR37L1 G protein-coupled receptor 37 like 1
HFE hemochromatosis
HLA-DRB6 major histocompatibility complex, class II, DR beta 6 (pseudogene)
HLF hepatic leukemia factor
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HRH4 histamine receptor H4
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFNA14 interferon, alpha 14
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
KLHL24 kelch-like family member 24
KLHL29 kelch-like family member 29
LIMCH1 LIM and calponin homology domains 1
LPIN1 lipin 1
LPP LIM domain containing preferred translocation partner in lipoma
MAGOH2P mago-nashi homolog 2, pseudogene
MAPK7 mitogen-activated protein kinase 7
MAX MYC associated factor X
MED16 mediator complex subunit 16
METTL7A methyltransferase like 7A
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MYO10 myosin X
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NIPAL2 NIPA-like domain containing 2
NKX3-2 NK3 homeobox 2
NOL12 nucleolar protein 12
NR4A1 nuclear receptor subfamily 4, group A, member 1
NRSN2 neurensin 2
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2
OSBP2 oxysterol binding protein 2
PARD6B par-6 family cell polarity regulator beta
PHF3 PHD finger protein 3
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4
PITX2 paired-like homeodomain 2
PKD2L2 polycystic kidney disease 2-like 2
PLA2G3 phospholipase A2, group III
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F
PRDX2 peroxiredoxin 2
PVR poliovirus receptor
RAB11B RAB11B, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAB6A RAB6A, member RAS oncogene family
RANBP3 RAN binding protein 3
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RHOBTB2 Rho-related BTB domain containing 2
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RNF43 ring finger protein 43
RPL10 ribosomal protein L10
RYR2 ryanodine receptor 2 (cardiac)
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SFTPB surfactant protein B
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOS2 son of sevenless homolog 2 (Drosophila)
SOX12 SRY (sex determining region Y)-box 12
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TBXA2R thromboxane A2 receptor
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRIM2 tripartite motif containing 2
TSC22D3 TSC22 domain family, member 3
UPK3A uroplakin 3A
UPK3B uroplakin 3B
UPP1 uridine phosphorylase 1
USP27X ubiquitin specific peptidase 27, X-linked
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VEGFA vascular endothelial growth factor A
VGF VGF nerve growth factor inducible
ZNF141 zinc finger protein 141
ZNF280A zinc finger protein 280A
ZNF552 zinc finger protein 552

decreased expression

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ADRA2C adrenoceptor alpha 2C
AFF4 AF4/FMR2 family, member 4
AHCTF1 AT hook containing transcription factor 1
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ANKRD36 ankyrin repeat domain 36
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARL15 ADP-ribosylation factor-like 15
BAK1 BCL2-antagonist/killer 1
BTBD2 BTB (POZ) domain containing 2
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCDC130 coiled-coil domain containing 130
CCDC68 coiled-coil domain containing 68
CCDC85C coiled-coil domain containing 85C
CCNT1 cyclin T1
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CENPQ centromere protein Q
CHMP7 charged multivesicular body protein 7
CIDEC cell death-inducing DFFA-like effector c
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CRELD2 cysteine-rich with EGF-like domains 2
CRYBB2P1 crystallin, beta B2 pseudogene 1
DGKE diacylglycerol kinase, epsilon 64kDa
DPH2 DPH2 homolog (S. cerevisiae)
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha)
EAF2 ELL associated factor 2
EMD emerin
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ESRP2 epithelial splicing regulatory protein 2
F8 coagulation factor VIII, procoagulant component
FBXL4 F-box and leucine-rich repeat protein 4
FICD FIC domain containing
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GAREM GRB2 associated, regulator of MAPK1
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HAUS2 HAUS augmin-like complex, subunit 2
HYI hydroxypyruvate isomerase (putative)
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IRF7 interferon regulatory factor 7
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KRT8P12 keratin 8 pseudogene 12
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
LRRC8E leucine rich repeat containing 8 family, member E
LYPLA2P1 lysophospholipase II pseudogene 1
MAP1S microtubule-associated protein 1S
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MAPK12 mitogen-activated protein kinase 12
MAPKBP1 mitogen-activated protein kinase binding protein 1
MCC mutated in colorectal cancers
MTERF1 mitochondrial transcription termination factor 1
MTHFSD methenyltetrahydrofolate synthetase domain containing
NABP2 nucleic acid binding protein 2
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NARFL nuclear prelamin A recognition factor-like
NKAIN1 Na+/K+ transporting ATPase interacting 1
NR1H3 nuclear receptor subfamily 1, group H, member 3
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PACS2 phosphofurin acidic cluster sorting protein 2
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PDZRN3 PDZ domain containing ring finger 3
PGAP1 post-GPI attachment to proteins 1
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLA2G15 phospholipase A2, group XV
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLEK2 pleckstrin 2
PODXL2 podocalyxin-like 2
PPAN peter pan homolog (Drosophila)
PRODH proline dehydrogenase (oxidase) 1
PVRL3 poliovirus receptor-related 3
PYCRL pyrroline-5-carboxylate reductase-like
QDPR quinoid dihydropteridine reductase
REPS2 RALBP1 associated Eps domain containing 2
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNF19B ring finger protein 19B
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPH3AL rabphilin 3A-like (without C2 domains)
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
RWDD3 RWD domain containing 3
SCMH1 sex comb on midleg homolog 1 (Drosophila)
SLC46A3 solute carrier family 46, member 3
STBD1 starch binding domain 1
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TDRD1 tudor domain containing 1
TESK1 testis-specific kinase 1
TOLLIP toll interacting protein
TRABD TraB domain containing
TTC30A tetratricopeptide repeat domain 30A
UBQLN4 ubiquilin 4
ZBTB48 zinc finger and BTB domain containing 48
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF226 zinc finger protein 226
ZNF276 zinc finger protein 276
ZNF280D zinc finger protein 280D
ZNF35 zinc finger protein 35
ZNF432 zinc finger protein 432
ZNF510 zinc finger protein 510
ZNF767P zinc finger family member 767, pseudogene
ZSCAN26 zinc finger and SCAN domain containing 26