haloperidol-7003 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the haloperidol-7003 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AFAP1 actin filament associated protein 1
AIM2 absent in melanoma 2
ANTXR1 anthrax toxin receptor 1
APOM apolipoprotein M
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATP10A ATPase, class V, type 10A
C7ORF43 chromosome 7 open reading frame 43
CALCR calcitonin receptor
CD82 CD82 molecule
CDKN2A cyclin-dependent kinase inhibitor 2A
CHRM3 cholinergic receptor, muscarinic 3
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric)
COQ6 coenzyme Q6 monooxygenase
CST6 cystatin E/M
CTNS cystinosin, lysosomal cystine transporter
CXCR4 chemokine (C-X-C motif) receptor 4
ELSPBP1 epididymal sperm binding protein 1
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
EPOR erythropoietin receptor
EXOSC1 exosome component 1
FAM120C family with sequence similarity 120C
FAM53B family with sequence similarity 53, member B
FOLR1 folate receptor 1 (adult)
FZD7 frizzled class receptor 7
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GFER growth factor, augmenter of liver regeneration
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLS2 glutaminase 2 (liver, mitochondrial)
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPM6A glycoprotein M6A
GPR137 G protein-coupled receptor 137
HBB hemoglobin, beta
HOXC10 homeobox C10
IFI35 interferon-induced protein 35
KATNB1 katanin p80 (WD repeat containing) subunit B 1
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KLF3 Kruppel-like factor 3 (basic)
KREMEN2 kringle containing transmembrane protein 2
LDLR low density lipoprotein receptor
LONP2 lon peptidase 2, peroxisomal
MALT1 MALT1 paracaspase
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
NCOA1 nuclear receptor coactivator 1
NFIB nuclear factor I/B
NPFFR1 neuropeptide FF receptor 1
NPTX1 neuronal pentraxin I
PAOX polyamine oxidase (exo-N4-amino)
PCDHB3 protocadherin beta 3
PHF20 PHD finger protein 20
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PKNOX1 PBX/knotted 1 homeobox 1
PML promyelocytic leukemia
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRKD3 protein kinase D3
PRPF18 pre-mRNA processing factor 18
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PRSS16 protease, serine, 16 (thymus)
PSD4 pleckstrin and Sec7 domain containing 4
PSG11 pregnancy specific beta-1-glycoprotein 11
PSG4 pregnancy specific beta-1-glycoprotein 4
PTP4A3 protein tyrosine phosphatase type IVA, member 3
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAD52 RAD52 homolog (S. cerevisiae)
RRAGD Ras-related GTP binding D
RRBP1 ribosome binding protein 1
S100A13 S100 calcium binding protein A13
SBF1 SET binding factor 1
SCUBE3 signal peptide, CUB domain, EGF-like 3
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SETD8 SET domain containing (lysine methyltransferase) 8
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLIT2 slit homolog 2 (Drosophila)
SOS2 son of sevenless homolog 2 (Drosophila)
SPTAN1 spectrin, alpha, non-erythrocytic 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
ST7 suppression of tumorigenicity 7
TACC1 transforming, acidic coiled-coil containing protein 1
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TESC tescalcin
TMC5 transmembrane channel-like 5
TMEM63A transmembrane protein 63A
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TPM1 tropomyosin 1 (alpha)
TTC38 tetratricopeptide repeat domain 38
UBTD1 ubiquitin domain containing 1
UNC5B unc-5 homolog B (C. elegans)
WIZ widely interspaced zinc finger motifs
XK X-linked Kx blood group
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF16 zinc finger protein 16
ZNF45 zinc finger protein 45
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARID3A AT rich interactive domain 3A (BRIGHT-like)
BAGE B melanoma antigen
BAK1 BCL2-antagonist/killer 1
BCL9 B-cell CLL/lymphoma 9
BCOR BCL6 corepressor
BCORL1 BCL6 corepressor-like 1
C10ORF95 chromosome 10 open reading frame 95
C14ORF132 chromosome 14 open reading frame 132
C22ORF29 chromosome 22 open reading frame 29
C5 complement component 5
C5ORF45 chromosome 5 open reading frame 45
CAMKMT calmodulin-lysine N-methyltransferase
CAPRIN2 caprin family member 2
CBR4 carbonyl reductase 4
CCDC85C coiled-coil domain containing 85C
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CENPJ centromere protein J
CEP131 centrosomal protein 131kDa
CHML choroideremia-like (Rab escort protein 2)
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
COQ3 coenzyme Q3 methyltransferase
CPPED1 calcineurin-like phosphoesterase domain containing 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DTX4 deltex 4, E3 ubiquitin ligase
EPHA2 EPH receptor A2
FLCN folliculin
FMO4 flavin containing monooxygenase 4
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GAN gigaxonin
GPX2 glutathione peroxidase 2
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HCFC2 host cell factor C2
HHLA3 HERV-H LTR-associating 3
HIST1H2BC histone cluster 1, H2bc
HIST1H2BJ histone cluster 1, H2bj
HIST1H3B histone cluster 1, H3b
IFT81 intraflagellar transport 81
IRF2 interferon regulatory factor 2
JMJD4 jumonji domain containing 4
KLF2 Kruppel-like factor 2
LAMA5 laminin, alpha 5
LIG4 ligase IV, DNA, ATP-dependent
LMBR1L limb development membrane protein 1-like
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRRC37A2 leucine rich repeat containing 37, member A2
LYRM9 LYR motif containing 9
MECR mitochondrial trans-2-enoyl-CoA reductase
MFSD11 major facilitator superfamily domain containing 11
MITF microphthalmia-associated transcription factor
MYH9 myosin, heavy chain 9, non-muscle
MYO1E myosin IE
NCS1 neuronal calcium sensor 1
NDE1 nudE neurodevelopment protein 1
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NRGN neurogranin (protein kinase C substrate, RC3)
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
RNF126P1 ring finger protein 126 pseudogene 1
RNF31 ring finger protein 31
RPL13P5 ribosomal protein L13 pseudogene 5
RUFY2 RUN and FYVE domain containing 2
SARS2 seryl-tRNA synthetase 2, mitochondrial
SCMH1 sex comb on midleg homolog 1 (Drosophila)
SCN1B sodium channel, voltage gated, type I beta subunit
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SHARPIN SHANK-associated RH domain interactor
SHPK sedoheptulokinase
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLMO1 slowmo homolog 1 (Drosophila)
SP1 Sp1 transcription factor
STARD5 StAR-related lipid transfer (START) domain containing 5
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TCTN2 tectonic family member 2
THBS3 thrombospondin 3
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TLN1 talin 1
TMEM180 transmembrane protein 180
TMEM2 transmembrane protein 2
UBQLN4 ubiquilin 4
USP18 ubiquitin specific peptidase 18
USP36 ubiquitin specific peptidase 36
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VAX2 ventral anterior homeobox 2
WDR62 WD repeat domain 62
WDR91 WD repeat domain 91
YEATS2 YEATS domain containing 2
ZNF254 zinc finger protein 254