haloperidol-6963 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the haloperidol-6963 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ANGPT4 angiopoietin 4
ANKMY1 ankyrin repeat and MYND domain containing 1
AP4S1 adaptor-related protein complex 4, sigma 1 subunit
APLP1 amyloid beta (A4) precursor-like protein 1
AQR aquarius intron-binding spliceosomal factor
AURKA aurora kinase A
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
C7ORF69 chromosome 7 open reading frame 69
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CAPN5 calpain 5
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CD52 CD52 molecule
CDC25A cell division cycle 25A
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CLIP4 CAP-GLY domain containing linker protein family, member 4
CNKSR2 connector enhancer of kinase suppressor of Ras 2
COL10A1 collagen, type X, alpha 1
COL6A1 collagen, type VI, alpha 1
DBN1 drebrin 1
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DNAAF1 dynein, axonemal, assembly factor 1
DUSP10 dual specificity phosphatase 10
DUX1 double homeobox 1
DVL3 dishevelled segment polarity protein 3
EMC1 ER membrane protein complex subunit 1
ESR2 estrogen receptor 2 (ER beta)
FGFR4 fibroblast growth factor receptor 4
FILIP1L filamin A interacting protein 1-like
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GPR3 G protein-coupled receptor 3
GSAP gamma-secretase activating protein
HAMP hepcidin antimicrobial peptide
HLA-E major histocompatibility complex, class I, E
IFNA10 interferon, alpha 10
IL1A interleukin 1, alpha
INHBA inhibin, beta A
IQCC IQ motif containing C
IRF2BP1 interferon regulatory factor 2 binding protein 1
IRF6 interferon regulatory factor 6
ITGA10 integrin, alpha 10
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1
KIF1C kinesin family member 1C
KLF1 Kruppel-like factor 1 (erythroid)
LTC4S leukotriene C4 synthase
MAPT microtubule-associated protein tau
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
NRF1 nuclear respiratory factor 1
PDAP1 PDGFA associated protein 1
PEX3 peroxisomal biogenesis factor 3
PHLDB1 pleckstrin homology-like domain, family B, member 1
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PMEL premelanosome protein
POLL polymerase (DNA directed), lambda
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRELP proline/arginine-rich end leucine-rich repeat protein
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PRPF18 pre-mRNA processing factor 18
PRUNE2 prune homolog 2 (Drosophila)
PSD4 pleckstrin and Sec7 domain containing 4
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RIN2 Ras and Rab interactor 2
RLN1 relaxin 1
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RNF170 ring finger protein 170
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RRBP1 ribosome binding protein 1
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
RUFY3 RUN and FYVE domain containing 3
SBF1 SET binding factor 1
SFTPB surfactant protein B
SIK1 salt-inducible kinase 1
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2
SNCG synuclein, gamma (breast cancer-specific protein 1)
SOCS3 suppressor of cytokine signaling 3
SPTAN1 spectrin, alpha, non-erythrocytic 1
ST7 suppression of tumorigenicity 7
TESPA1 thymocyte expressed, positive selection associated 1
TEX13B testis expressed 13B
TFPI2 tissue factor pathway inhibitor 2
TMEM212 transmembrane protein 212
TMEM53 transmembrane protein 53
TMEM63A transmembrane protein 63A
TNK1 tyrosine kinase, non-receptor, 1
TNS2 tensin 2
TRIM49 tripartite motif containing 49
TROVE2 TROVE domain family, member 2
TUBA3C tubulin, alpha 3c
ULK2 unc-51 like autophagy activating kinase 2
XAB2 XPA binding protein 2
ZBTB39 zinc finger and BTB domain containing 39
ZCCHC24 zinc finger, CCHC domain containing 24
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF202 zinc finger protein 202

decreased expression

Symbol Name
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ACYP2 acylphosphatase 2, muscle type
AKR1C3 aldo-keto reductase family 1, member C3
ANKRD36B ankyrin repeat domain 36B
ATAD5 ATPase family, AAA domain containing 5
BAK1 BCL2-antagonist/killer 1
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide
BRPF1 bromodomain and PHD finger containing, 1
C1ORF115 chromosome 1 open reading frame 115
C21ORF91 chromosome 21 open reading frame 91
C5ORF30 chromosome 5 open reading frame 30
CCDC25 coiled-coil domain containing 25
CCDC85C coiled-coil domain containing 85C
CCNE1 cyclin E1
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHAF1B chromatin assembly factor 1, subunit B (p60)
CHKB choline kinase beta
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
COBL cordon-bleu WH2 repeat protein
COPS7A COP9 signalosome subunit 7A
CTSK cathepsin K
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DENND4C DENN/MADD domain containing 4C
DGKD diacylglycerol kinase, delta 130kDa
DHTKD1 dehydrogenase E1 and transketolase domain containing 1
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DOCK1 dedicator of cytokinesis 1
FA2H fatty acid 2-hydroxylase
FBP1 fructose-1,6-bisphosphatase 1
FBXO31 F-box protein 31
FKBP10 FK506 binding protein 10, 65 kDa
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FOXA1 forkhead box A1
FOXK2 forkhead box K2
FUZ fuzzy planar cell polarity protein
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
HAUS6 HAUS augmin-like complex, subunit 6
HIRIP3 HIRA interacting protein 3
HOOK1 hook microtubule-tethering protein 1
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IRF9 interferon regulatory factor 9
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
JMJD4 jumonji domain containing 4
KIF16B kinesin family member 16B
LINS lines homolog (Drosophila)
LZTR1 leucine-zipper-like transcription regulator 1
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MB myoglobin
MCM3AP-AS1 MCM3AP antisense RNA 1
MDN1 MDN1, midasin homolog (yeast)
MED24 mediator complex subunit 24
METTL21B methyltransferase like 21B
MOCS3 molybdenum cofactor synthesis 3
MON1B MON1 secretory trafficking family member B
MOSPD3 motile sperm domain containing 3
MXD3 MAX dimerization protein 3
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma
NCAM2 neural cell adhesion molecule 2
NR1H3 nuclear receptor subfamily 1, group H, member 3
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
POTEKP POTE ankyrin domain family, member K, pseudogene
PPL periplakin
PPP2R2D protein phosphatase 2, regulatory subunit B, delta
PROCR protein C receptor, endothelial
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
SCAMP4 secretory carrier membrane protein 4
SH2B2 SH2B adaptor protein 2
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SMAD7 SMAD family member 7
SP140L SP140 nuclear body protein-like
SPINK4 serine peptidase inhibitor, Kazal type 4
SSFA2 sperm specific antigen 2
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STARD13 StAR-related lipid transfer (START) domain containing 13
STK25 serine/threonine kinase 25
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMEM160 transmembrane protein 160
TMEM2 transmembrane protein 2
TMEM254 transmembrane protein 254
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TPST2 tyrosylprotein sulfotransferase 2
TRAPPC13 trafficking protein particle complex 13
TXLNA taxilin alpha
UBQLN4 ubiquilin 4
UNC13B unc-13 homolog B (C. elegans)
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WDR60 WD repeat domain 60
ZBTB24 zinc finger and BTB domain containing 24
ZFHX3 zinc finger homeobox 3
ZFP30 ZFP30 zinc finger protein
ZKSCAN4 zinc finger with KRAB and SCAN domains 4
ZNF189 zinc finger protein 189
ZNF268 zinc finger protein 268
ZNF273 zinc finger protein 273
ZNF552 zinc finger protein 552
ZNF768 zinc finger protein 768
ZNF813 zinc finger protein 813