haloperidol-6960 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the haloperidol-6960 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACO2 aconitase 2, mitochondrial
ACSL1 acyl-CoA synthetase long-chain family member 1
AKAP11 A kinase (PRKA) anchor protein 11
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
APOC1 apolipoprotein C-I
AQP3 aquaporin 3 (Gill blood group)
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
AVL9 AVL9 homolog (S. cerevisiase)
BLVRA biliverdin reductase A
BTD biotinidase
C21ORF2 chromosome 21 open reading frame 2
CCDC71 coiled-coil domain containing 71
CCNO cyclin O
CDK3 cyclin-dependent kinase 3
CEP135 centrosomal protein 135kDa
CIC capicua transcriptional repressor
CNGB3 cyclic nucleotide gated channel beta 3
CPE carboxypeptidase E
CREM cAMP responsive element modulator
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DTNA dystrobrevin, alpha
DXO decapping exoribonuclease
EHD2 EH-domain containing 2
ELP3 elongator acetyltransferase complex subunit 3
ENPEP glutamyl aminopeptidase (aminopeptidase A)
EXTL3 exostosin-like glycosyltransferase 3
FCAR Fc fragment of IgA receptor
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FGGY FGGY carbohydrate kinase domain containing
FKBP5 FK506 binding protein 5
FNTB farnesyltransferase, CAAX box, beta
FOXJ3 forkhead box J3
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
GDF3 growth differentiation factor 3
GFI1 growth factor independent 1 transcription repressor
GPRC5C G protein-coupled receptor, class C, group 5, member C
HCFC1 host cell factor C1
HSPA12A heat shock 70kDa protein 12A
IFT140 intraflagellar transport 140
INSIG1 insulin induced gene 1
KDM4B lysine (K)-specific demethylase 4B
KDM5A lysine (K)-specific demethylase 5A
LAT2 linker for activation of T cells family, member 2
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LOC257152 uncharacterized LOC257152
LPIN1 lipin 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MEIS1 Meis homeobox 1
MFN2 mitofusin 2
MSI1 musashi RNA-binding protein 1
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRF1 nuclear respiratory factor 1
OSGIN1 oxidative stress induced growth inhibitor 1
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PECR peroxisomal trans-2-enoyl-CoA reductase
PKD1 polycystic kidney disease 1 (autosomal dominant)
PLEKHO1 pleckstrin homology domain containing, family O member 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPARA peroxisome proliferator-activated receptor alpha
PTPN21 protein tyrosine phosphatase, non-receptor type 21
RAD51B RAD51 paralog B
RARA retinoic acid receptor, alpha
RBM19 RNA binding motif protein 19
RGS12 regulator of G-protein signaling 12
RNF19B ring finger protein 19B
RNF24 ring finger protein 24
RNMT RNA (guanine-7-) methyltransferase
RPS3A ribosomal protein S3A
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RSL1D1 ribosomal L1 domain containing 1
RYK receptor-like tyrosine kinase
SETX senataxin
SGSM3 small G protein signaling modulator 3
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC41A3 solute carrier family 41, member 3
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SNTA1 syntrophin, alpha 1
SORBS1 sorbin and SH3 domain containing 1
SOS2 son of sevenless homolog 2 (Drosophila)
SPTBN1 spectrin, beta, non-erythrocytic 1
TAOK2 TAO kinase 2
TBX19 T-box 19
TEC tec protein tyrosine kinase
TRAF2 TNF receptor-associated factor 2
TRAK1 trafficking protein, kinesin binding 1
TRPM3 transient receptor potential cation channel, subfamily M, member 3
VLDLR very low density lipoprotein receptor
WDR62 WD repeat domain 62
WSB1 WD repeat and SOCS box containing 1
YLPM1 YLP motif containing 1
ZBTB6 zinc finger and BTB domain containing 6
ZCCHC24 zinc finger, CCHC domain containing 24
ZMIZ2 zinc finger, MIZ-type containing 2

decreased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ABLIM3 actin binding LIM protein family, member 3
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ARC activity-regulated cytoskeleton-associated protein
ASAP1-IT1 ASAP1 intronic transcript 1
BBS10 Bardet-Biedl syndrome 10
C16ORF59 chromosome 16 open reading frame 59
C2ORF44 chromosome 2 open reading frame 44
C9ORF9 chromosome 9 open reading frame 9
CBR4 carbonyl reductase 4
CCDC130 coiled-coil domain containing 130
CCDC176 coiled-coil domain containing 176
CCDC85C coiled-coil domain containing 85C
CCP110 centriolar coiled coil protein 110kDa
CINP cyclin-dependent kinase 2 interacting protein
CISH cytokine inducible SH2-containing protein
CXORF21 chromosome X open reading frame 21
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
ECHDC2 enoyl CoA hydratase domain containing 2
ECHDC3 enoyl CoA hydratase domain containing 3
EFCAB2 EF-hand calcium binding domain 2
EGLN3 egl-9 family hypoxia-inducible factor 3
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
EPHA2 EPH receptor A2
FAM188A family with sequence similarity 188, member A
FAM50B family with sequence similarity 50, member B
FANCE Fanconi anemia, complementation group E
FCHO1 FCH domain only 1
FLT4 fms-related tyrosine kinase 4
GADD45G growth arrest and DNA-damage-inducible, gamma
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
GUF1 GUF1 GTPase homolog (S. cerevisiae)
HIST1H2BC histone cluster 1, H2bc
HIST1H2BN histone cluster 1, H2bn
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KAT2A K(lysine) acetyltransferase 2A
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KLHL21 kelch-like family member 21
L2HGDH L-2-hydroxyglutarate dehydrogenase
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LINS lines homolog (Drosophila)
LOC100287590 uncharacterized LOC100287590
LRRC20 leucine rich repeat containing 20
LRRC37A2 leucine rich repeat containing 37, member A2
LYRM9 LYR motif containing 9
MAN2C1 mannosidase, alpha, class 2C, member 1
MED24 mediator complex subunit 24
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MOCS3 molybdenum cofactor synthesis 3
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
PACS1 phosphofurin acidic cluster sorting protein 1
PDE12 phosphodiesterase 12
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
POLR1B polymerase (RNA) I polypeptide B, 128kDa
PRICKLE3 prickle homolog 3 (Drosophila)
PTCD2 pentatricopeptide repeat domain 2
RAB3A RAB3A, member RAS oncogene family
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1
RWDD3 RWD domain containing 3
SAMD9 sterile alpha motif domain containing 9
SCAI suppressor of cancer cell invasion
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SYBU syntabulin (syntaxin-interacting)
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
THBS3 thrombospondin 3
TMC5 transmembrane channel-like 5
TMEM212 transmembrane protein 212
TNS3 tensin 3
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TUBA3C tubulin, alpha 3c
TUBA4A tubulin, alpha 4a
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
USP18 ubiquitin specific peptidase 18
USP6 ubiquitin specific peptidase 6
VASH2 vasohibin 2
VGF VGF nerve growth factor inducible
WDR43 WD repeat domain 43
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZBTB25 zinc finger and BTB domain containing 25
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF16 zinc finger protein 16
ZNF205 zinc finger protein 205
ZNF280D zinc finger protein 280D
ZNF408 zinc finger protein 408
ZNF552 zinc finger protein 552
ZNF675 zinc finger protein 675
ZNF721 zinc finger protein 721
ZNF768 zinc finger protein 768