haloperidol-492 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the haloperidol-492 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
AGXT alanine-glyoxylate aminotransferase
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ANK2 ankyrin 2, neuronal
ARSA arylsulfatase A
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
AVPR1B arginine vasopressin receptor 1B
C1QTNF1 C1q and tumor necrosis factor related protein 1
C7ORF26 chromosome 7 open reading frame 26
CACTIN cactin, spliceosome C complex subunit
CADM3 cell adhesion molecule 3
CAV3 caveolin 3
CCNG2 cyclin G2
CD6 CD6 molecule
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHUK conserved helix-loop-helix ubiquitous kinase
CREM cAMP responsive element modulator
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DMBT1 deleted in malignant brain tumors 1
DRP2 dystrophin related protein 2
E2F5 E2F transcription factor 5, p130-binding
EHMT2 euchromatic histone-lysine N-methyltransferase 2
EIF4E2 eukaryotic translation initiation factor 4E family member 2
ELF4 E74-like factor 4 (ets domain transcription factor)
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
EPS8L3 EPS8-like 3
FBXO11 F-box protein 11
FKBP8 FK506 binding protein 8, 38kDa
FNDC3A fibronectin type III domain containing 3A
GAB2 GRB2-associated binding protein 2
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GFOD1 glucose-fructose oxidoreductase domain containing 1
GMIP GEM interacting protein
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
HAO2 hydroxyacid oxidase 2 (long chain)
HEXIM1 hexamethylene bis-acetamide inducible 1
HMGA2 high mobility group AT-hook 2
HSPA12A heat shock 70kDa protein 12A
HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular)
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
INHBC inhibin, beta C
KIAA0141 KIAA0141
KLF6 Kruppel-like factor 6
KLHL25 kelch-like family member 25
L1CAM L1 cell adhesion molecule
LINC00216 long intergenic non-protein coding RNA 216
METAP2 methionyl aminopeptidase 2
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
MTUS1 microtubule associated tumor suppressor 1
MZF1 myeloid zinc finger 1
NELL2 NEL-like 2 (chicken)
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NOD1 nucleotide-binding oligomerization domain containing 1
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4
PARVA parvin, alpha
PCDHB3 protocadherin beta 3
PIGV phosphatidylinositol glycan anchor biosynthesis, class V
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PLAUR plasminogen activator, urokinase receptor
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PSPH phosphoserine phosphatase
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTN pleiotrophin
PTPRN protein tyrosine phosphatase, receptor type, N
RPS2 ribosomal protein S2
RUNDC3A RUN domain containing 3A
S100A1 S100 calcium binding protein A1
SAFB2 scaffold attachment factor B2
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
SEZ6L seizure related 6 homolog (mouse)-like
SFTPC surfactant protein C
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SPINK4 serine peptidase inhibitor, Kazal type 4
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SSBP2 single-stranded DNA binding protein 2
TAS2R4 taste receptor, type 2, member 4
TAZ tafazzin
TCP11L1 t-complex 11, testis-specific-like 1
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNIP1 TNFAIP3 interacting protein 1
TRA T cell receptor alpha locus
TSPAN32 tetraspanin 32
TTR transthyretin
UBL3 ubiquitin-like 3
UMPS uridine monophosphate synthetase
WAS Wiskott-Aldrich syndrome
WDR18 WD repeat domain 18
XPA xeroderma pigmentosum, complementation group A
ZNF358 zinc finger protein 358
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
AATK apoptosis-associated tyrosine kinase
ABHD17B abhydrolase domain containing 17B
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACSL5 acyl-CoA synthetase long-chain family member 5
AEN apoptosis enhancing nuclease
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ALPK1 alpha-kinase 1
ALX3 ALX homeobox 3
ANXA2P3 annexin A2 pseudogene 3
ASCC1 activating signal cointegrator 1 complex subunit 1
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
BDH1 3-hydroxybutyrate dehydrogenase, type 1
BEGAIN brain-enriched guanylate kinase-associated
BRS3 bombesin-like receptor 3
CBX8 chromobox homolog 8
CCDC170 coiled-coil domain containing 170
CD5 CD5 molecule
CD70 CD70 molecule
CLCF1 cardiotrophin-like cytokine factor 1
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CORO1A coronin, actin binding protein, 1A
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae)
CRYAB crystallin, alpha B
CTRB2 chymotrypsinogen B2
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
DAGLA diacylglycerol lipase, alpha
DEFA5 defensin, alpha 5, Paneth cell-specific
DGKD diacylglycerol kinase, delta 130kDa
DHTKD1 dehydrogenase E1 and transketolase domain containing 1
DLK2 delta-like 2 homolog (Drosophila)
ERN2 endoplasmic reticulum to nucleus signaling 2
EVPL envoplakin
EXOC3 exocyst complex component 3
FAM188A family with sequence similarity 188, member A
FBXL7 F-box and leucine-rich repeat protein 7
FGL1 fibrinogen-like 1
FOXO1 forkhead box O1
GBAP1 glucosidase, beta, acid pseudogene 1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GMPPB GDP-mannose pyrophosphorylase B
GPR27 G protein-coupled receptor 27
GRIP2 glutamate receptor interacting protein 2
HCLS1 hematopoietic cell-specific Lyn substrate 1
HIRIP3 HIRA interacting protein 3
HIST1H3E histone cluster 1, H3e
HOXA4 homeobox A4
HOXC4 homeobox C4
IL19 interleukin 19
JMJD4 jumonji domain containing 4
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
KRT5 keratin 5, type II
LGALS9 lectin, galactoside-binding, soluble, 9
MEP1B meprin A, beta
MMP2 matrix metallopeptidase 2
MTRF1 mitochondrial translational release factor 1
MUC2 mucin 2, oligomeric mucus/gel-forming
NES nestin
NLRX1 NLR family member X1
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NPR3 natriuretic peptide receptor 3
NXF2 nuclear RNA export factor 2
PADI1 peptidyl arginine deiminase, type I
PARP16 poly (ADP-ribose) polymerase family, member 16
PHKG1 phosphorylase kinase, gamma 1 (muscle)
PHOX2B paired-like homeobox 2b
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PMEPA1 prostate transmembrane protein, androgen induced 1
POMT2 protein-O-mannosyltransferase 2
PON3 paraoxonase 3
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
PQLC2 PQ loop repeat containing 2
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RDH5 retinol dehydrogenase 5 (11-cis/9-cis)
SCAND1 SCAN domain containing 1
SDC3 syndecan 3
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SPTBN2 spectrin, beta, non-erythrocytic 2
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
STAT4 signal transducer and activator of transcription 4
TLR5 toll-like receptor 5
TMEM242 transmembrane protein 242
TMSB4Y thymosin beta 4, Y-linked
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TUBA4B tubulin, alpha 4b
UBOX5 U-box domain containing 5
VEGFB vascular endothelial growth factor B
ZBTB22 zinc finger and BTB domain containing 22
ZFHX2 zinc finger homeobox 2
ZFP36 ZFP36 ring finger protein
ZNF134 zinc finger protein 134
ZNF197 zinc finger protein 197
ZNHIT2 zinc finger, HIT-type containing 2