haloperidol-4427 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the haloperidol-4427 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRV1 adhesion G protein-coupled receptor V1
ARTN artemin
ASIC4 acid sensing (proton gated) ion channel family member 4
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
C4ORF29 chromosome 4 open reading frame 29
CAMK4 calcium/calmodulin-dependent protein kinase IV
CCNK cyclin K
CCR8 chemokine (C-C motif) receptor 8
CD2 CD2 molecule
CDC14B cell division cycle 14B
CEP290 centrosomal protein 290kDa
CTBP2 C-terminal binding protein 2
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DCTN1 dynactin 1
DGKE diacylglycerol kinase, epsilon 64kDa
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DSC2 desmocollin 2
EDRF1 erythroid differentiation regulatory factor 1
ELL elongation factor RNA polymerase II
EML2 echinoderm microtubule associated protein like 2
ENG endoglin
ENOX2 ecto-NOX disulfide-thiol exchanger 2
EVI5 ecotropic viral integration site 5
F5 coagulation factor V (proaccelerin, labile factor)
FAM63A family with sequence similarity 63, member A
FAS Fas cell surface death receptor
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GUSBP3 glucuronidase, beta pseudogene 3
HIRA histone cell cycle regulator
HMOX1 heme oxygenase 1
IL21R interleukin 21 receptor
IL6ST interleukin 6 signal transducer
INSIG1 insulin induced gene 1
ITGA7 integrin, alpha 7
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KHK ketohexokinase (fructokinase)
KLHL4 kelch-like family member 4
KRT86 keratin 86, type II
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MFAP3L microfibrillar-associated protein 3-like
MUC1 mucin 1, cell surface associated
MYCNOS MYCN opposite strand
NCDN neurochondrin
NDNF neuron-derived neurotrophic factor
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NPIPB3 nuclear pore complex interacting protein family, member B3
NPTX1 neuronal pentraxin I
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7
OR2J2 olfactory receptor, family 2, subfamily J, member 2
PDE4DIP phosphodiesterase 4D interacting protein
PHF8 PHD finger protein 8
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLCH1 phospholipase C, eta 1
PLEKHH3 pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
PLK3 polo-like kinase 3
PNMAL1 paraneoplastic Ma antigen family-like 1
PRKCB protein kinase C, beta
PURA purine-rich element binding protein A
PXDC1 PX domain containing 1
RHAG Rh-associated glycoprotein
RND1 Rho family GTPase 1
RNF17 ring finger protein 17
RNF208 ring finger protein 208
RPL7 ribosomal protein L7
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
RUNX1 runt-related transcription factor 1
SCN4A sodium channel, voltage gated, type IV alpha subunit
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SEPP1 selenoprotein P, plasma, 1
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SFRP4 secreted frizzled-related protein 4
SH3PXD2A SH3 and PX domains 2A
SIX3 SIX homeobox 3
SLAMF7 SLAM family member 7
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa
SP110 SP110 nuclear body protein
SPHK2 sphingosine kinase 2
SPTBN5 spectrin, beta, non-erythrocytic 5
TLR2 toll-like receptor 2
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TMEM40 transmembrane protein 40
TPM3 tropomyosin 3
TRPV2 transient receptor potential cation channel, subfamily V, member 2
TTLL3 tubulin tyrosine ligase-like family member 3
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
VDAC3 voltage-dependent anion channel 3
WBP4 WW domain binding protein 4
WDR1 WD repeat domain 1
ZBTB3 zinc finger and BTB domain containing 3
ZMIZ2 zinc finger, MIZ-type containing 2

decreased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ACAD10 acyl-CoA dehydrogenase family, member 10
ACSL5 acyl-CoA synthetase long-chain family member 5
AGO4 argonaute RISC catalytic component 4
AIRE autoimmune regulator
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
C11ORF16 chromosome 11 open reading frame 16
CCNJ cyclin J
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD82 CD82 molecule
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CIDEB cell death-inducing DFFA-like effector b
CLCN2 chloride channel, voltage-sensitive 2
CNGA1 cyclic nucleotide gated channel alpha 1
CNGB3 cyclic nucleotide gated channel beta 3
CNTN1 contactin 1
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CREB5 cAMP responsive element binding protein 5
DAGLA diacylglycerol lipase, alpha
DDN dendrin
ERN2 endoplasmic reticulum to nucleus signaling 2
EXD3 exonuclease 3'-5' domain containing 3
FAM110B family with sequence similarity 110, member B
FAM184A family with sequence similarity 184, member A
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FKBP5 FK506 binding protein 5
FRS2 fibroblast growth factor receptor substrate 2
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GJA9 gap junction protein, alpha 9, 59kDa
HHLA1 HERV-H LTR-associating 1
HIST1H2BN histone cluster 1, H2bn
HIST1H2BO histone cluster 1, H2bo
HIST1H3A histone cluster 1, H3a
HIST1H4D histone cluster 1, H4d
HIST2H2AA3 histone cluster 2, H2aa3
HLA-DMB major histocompatibility complex, class II, DM beta
HOXA7 homeobox A7
HOXC5 homeobox C5
HYI hydroxypyruvate isomerase (putative)
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IFNA14 interferon, alpha 14
KCTD17 potassium channel tetramerization domain containing 17
KLK7 kallikrein-related peptidase 7
LIME1 Lck interacting transmembrane adaptor 1
LOC100127972 uncharacterized LOC100127972
LRRC17 leucine rich repeat containing 17
LRRC37A4P leucine rich repeat containing 37, member A4, pseudogene
LRRC61 leucine rich repeat containing 61
LY96 lymphocyte antigen 96
LYRM9 LYR motif containing 9
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MDFI MyoD family inhibitor
MDM4 MDM4, p53 regulator
METTL16 methyltransferase like 16
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
MGP matrix Gla protein
MRPS18C mitochondrial ribosomal protein S18C
MYO1F myosin IF
NCS1 neuronal calcium sensor 1
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OR2B6 olfactory receptor, family 2, subfamily B, member 6
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PADI1 peptidyl arginine deiminase, type I
PDE12 phosphodiesterase 12
PENK proenkephalin
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
POMT2 protein-O-mannosyltransferase 2
PQLC2 PQ loop repeat containing 2
PTPRS protein tyrosine phosphatase, receptor type, S
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RUNDC3B RUN domain containing 3B
SCGB2A2 secretoglobin, family 2A, member 2
SCIN scinderin
SCN10A sodium channel, voltage gated, type X alpha subunit
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SETD8 SET domain containing (lysine methyltransferase) 8
SLC22A14 solute carrier family 22, member 14
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
SMO smoothened, frizzled class receptor
SPINK5 serine peptidase inhibitor, Kazal type 5
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TIMP4 TIMP metallopeptidase inhibitor 4
TMEM180 transmembrane protein 180
TUBA3D tubulin, alpha 3d
USB1 U6 snRNA biogenesis 1
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZNF428 zinc finger protein 428
ZNF510 zinc finger protein 510
ZNF76 zinc finger protein 76