haloperidol-2039 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the haloperidol-2039 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
ACSL4 acyl-CoA synthetase long-chain family member 4
ADK adenosine kinase
AP1AR adaptor-related protein complex 1 associated regulatory protein
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
ARL1 ADP-ribosylation factor-like 1
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1
ATP9B ATPase, class II, type 9B
ATRN attractin
BRCC3 BRCA1/BRCA2-containing complex, subunit 3
C19ORF66 chromosome 19 open reading frame 66
C6 complement component 6
CAST calpastatin
CCPG1 cell cycle progression 1
CFAP74 cilia and flagella associated protein 74
CLCC1 chloride channel CLIC-like 1
CPOX coproporphyrinogen oxidase
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CRY1 cryptochrome circadian clock 1
CTH cystathionine gamma-lyase
CTSS cathepsin S
CUL3 cullin 3
CUL4A cullin 4A
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DERL1 derlin 1
DMXL1 Dmx-like 1
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
EI24 etoposide induced 2.4
EID1 EP300 interacting inhibitor of differentiation 1
EIF4E eukaryotic translation initiation factor 4E
ELMO2 engulfment and cell motility 2
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FSCN3 fascin actin-bundling protein 3, testicular
GCA grancalcin, EF-hand calcium binding protein
GPR137B G protein-coupled receptor 137B
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H4J histone cluster 1, H4j
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1
IKZF5 IKAROS family zinc finger 5 (Pegasus)
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KIAA1033 KIAA1033
KLHL20 kelch-like family member 20
KLHL7 kelch-like family member 7
KRIT1 KRIT1, ankyrin repeat containing
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LPP LIM domain containing preferred translocation partner in lipoma
LTB4R leukotriene B4 receptor
MAGOHB mago-nashi homolog B (Drosophila)
MEF2A myocyte enhancer factor 2A
MEX3C mex-3 RNA binding family member C
MOB3B MOB kinase activator 3B
MPHOSPH9 M-phase phosphoprotein 9
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MST1 macrophage stimulating 1
MTF2 metal response element binding transcription factor 2
NACAP1 nascent-polypeptide-associated complex alpha polypeptide pseudogene 1
NDRG2 NDRG family member 2
PBX2 pre-B-cell leukemia homeobox 2
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLEK2 pleckstrin 2
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme
PTP4A1 protein tyrosine phosphatase type IVA, member 1
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1
RAB29 RAB29, member RAS oncogene family
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RBL2 retinoblastoma-like 2
RBM8A RNA binding motif protein 8A
RCAN1 regulator of calcineurin 1
RECQL RecQ helicase-like
RNASE3 ribonuclease, RNase A family, 3
RP2 retinitis pigmentosa 2 (X-linked recessive)
RPL7 ribosomal protein L7
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SCAPER S-phase cyclin A-associated protein in the ER
SDHAF3 succinate dehydrogenase complex assembly factor 3
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SLMO2 slowmo homolog 2 (Drosophila)
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SOAT1 sterol O-acyltransferase 1
SOCS5 suppressor of cytokine signaling 5
SRSF10 serine/arginine-rich splicing factor 10
STAG2 stromal antigen 2
SUMO1 small ubiquitin-like modifier 1
SYT13 synaptotagmin XIII
TES testin LIM domain protein
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TRAPPC11 trafficking protein particle complex 11
TSN translin
USF2 upstream transcription factor 2, c-fos interacting
WDR19 WD repeat domain 19
ZC3H7B zinc finger CCCH-type containing 7B
ZC4H2 zinc finger, C4H2 domain containing
ZIM2 zinc finger, imprinted 2
ZMYM1 zinc finger, MYM-type 1
ZNF426 zinc finger protein 426

decreased expression

Symbol Name
ACP6 acid phosphatase 6, lysophosphatidic
ADM adrenomedullin
ADM2 adrenomedullin 2
AGRP agouti related neuropeptide
AMT aminomethyltransferase
APOC2 apolipoprotein C-II
ARG1 arginase 1
ARMC6 armadillo repeat containing 6
ATF7IP2 activating transcription factor 7 interacting protein 2
ATXN2 ataxin 2
AVEN apoptosis, caspase activation inhibitor
BAHCC1 BAH domain and coiled-coil containing 1
BCL7C B-cell CLL/lymphoma 7C
C21ORF59 chromosome 21 open reading frame 59
C6ORF47 chromosome 6 open reading frame 47
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
CD1A CD1a molecule
CD248 CD248 molecule, endosialin
CD320 CD320 molecule
CES3 carboxylesterase 3
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
CNTD2 cyclin N-terminal domain containing 2
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CTAGE9 CTAGE family, member 9
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DGKD diacylglycerol kinase, delta 130kDa
DHDDS dehydrodolichyl diphosphate synthase
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
DUS1L dihydrouridine synthase 1-like (S. cerevisiae)
EHD4 EH-domain containing 4
ELP3 elongator acetyltransferase complex subunit 3
ERCC2 excision repair cross-complementation group 2
ERMP1 endoplasmic reticulum metallopeptidase 1
EXOC3 exocyst complex component 3
EXOSC10 exosome component 10
FAM86B1 family with sequence similarity 86, member B1
FANCF Fanconi anemia, complementation group F
FBXW4 F-box and WD repeat domain containing 4
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FOXK2 forkhead box K2
GMEB1 glucocorticoid modulatory element binding protein 1
GPS1 G protein pathway suppressor 1
GRPR gastrin-releasing peptide receptor
GSDMD gasdermin D
GSTK1 glutathione S-transferase kappa 1
HK1 hexokinase 1
HSPA14 heat shock 70kDa protein 14
IRF2BP1 interferon regulatory factor 2 binding protein 1
KIFAP3 kinesin-associated protein 3
KIFC1 kinesin family member C1
KLHL12 kelch-like family member 12
KRT38 keratin 38, type I
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial)
LHFPL2 lipoma HMGIC fusion partner-like 2
LRRC42 leucine rich repeat containing 42
MGMT O-6-methylguanine-DNA methyltransferase
MICALL2 MICAL-like 2
NUBP2 nucleotide binding protein 2
NUPL1 nucleoporin like 1
ODF2 outer dense fiber of sperm tails 2
PCSK7 proprotein convertase subtilisin/kexin type 7
PEMT phosphatidylethanolamine N-methyltransferase
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PMEL premelanosome protein
POTEKP POTE ankyrin domain family, member K, pseudogene
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
QPRT quinolinate phosphoribosyltransferase
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RHOH ras homolog family member H
S1PR4 sphingosine-1-phosphate receptor 4
SDF2L1 stromal cell-derived factor 2-like 1
SGK2 serum/glucocorticoid regulated kinase 2
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
STARD3 StAR-related lipid transfer (START) domain containing 3
STARD8 StAR-related lipid transfer (START) domain containing 8
STRA13 stimulated by retinoic acid 13
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative)
TMEM159 transmembrane protein 159
TMEM242 transmembrane protein 242
TMEM57 transmembrane protein 57
TMPRSS6 transmembrane protease, serine 6
TRAIP TRAF interacting protein
TRIM26 tripartite motif containing 26
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UNC93B1 unc-93 homolog B1 (C. elegans)
VRK2 vaccinia related kinase 2
WDR13 WD repeat domain 13
ZNF189 zinc finger protein 189
ZNF263 zinc finger protein 263
ZNF536 zinc finger protein 536
ZSCAN9 zinc finger and SCAN domain containing 9