guaifenesin-3814 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the guaifenesin-3814 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ARTN artemin
ATF5 activating transcription factor 5
ATHL1 ATH1, acid trehalase-like 1 (yeast)
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C11ORF16 chromosome 11 open reading frame 16
C7ORF69 chromosome 7 open reading frame 69
C8ORF44 chromosome 8 open reading frame 44
CCL24 chemokine (C-C motif) ligand 24
CD160 CD160 molecule
CD200 CD200 molecule
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CLTCL1 clathrin, heavy chain-like 1
COLEC10 collectin sub-family member 10 (C-type lectin)
CREBZF CREB/ATF bZIP transcription factor
CRHR1 corticotropin releasing hormone receptor 1
CRISP2 cysteine-rich secretory protein 2
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
DEFA4 defensin, alpha 4, corticostatin
DLG1 discs, large homolog 1 (Drosophila)
DOPEY2 dopey family member 2
EMID1 EMI domain containing 1
FGD2 FYVE, RhoGEF and PH domain containing 2
FGF6 fibroblast growth factor 6
FKBP10 FK506 binding protein 10, 65 kDa
FKBP6 FK506 binding protein 6, 36kDa
FLT1 fms-related tyrosine kinase 1
FUT2 fucosyltransferase 2 (secretor status included)
GFI1 growth factor independent 1 transcription repressor
GIPR gastric inhibitory polypeptide receptor
GJA8 gap junction protein, alpha 8, 50kDa
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GPR15 G protein-coupled receptor 15
GPR85 G protein-coupled receptor 85
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HPX hemopexin
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IGLL1 immunoglobulin lambda-like polypeptide 1
JUND jun D proto-oncogene
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KIF1C kinesin family member 1C
KITLG KIT ligand
KLK10 kallikrein-related peptidase 10
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LCAT lecithin-cholesterol acyltransferase
LTBP4 latent transforming growth factor beta binding protein 4
LUZP4 leucine zipper protein 4
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAGEA8 melanoma antigen family A8
MAN1A2 mannosidase, alpha, class 1A, member 2
MAPK11 mitogen-activated protein kinase 11
MECOM MDS1 and EVI1 complex locus
MED25 mediator complex subunit 25
METTL7A methyltransferase like 7A
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MPZ myelin protein zero
MT3 metallothionein 3
MYOZ1 myozenin 1
NPR1 natriuretic peptide receptor 1
NPTXR neuronal pentraxin receptor
OAZ3 ornithine decarboxylase antizyme 3
OMD osteomodulin
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OR7A17 olfactory receptor, family 7, subfamily A, member 17
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PDGFA platelet-derived growth factor alpha polypeptide
PHEX phosphate regulating endopeptidase homolog, X-linked
PKNOX2 PBX/knotted 1 homeobox 2
PNMA3 paraneoplastic Ma antigen 3
RARG retinoic acid receptor, gamma
RB1 retinoblastoma 1
RGS12 regulator of G-protein signaling 12
RORB RAR-related orphan receptor B
SAA3P serum amyloid A3 pseudogene
SERHL2 serine hydrolase-like 2
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SOCS1 suppressor of cytokine signaling 1
SRSF5 serine/arginine-rich splicing factor 5
STOML1 stomatin (EPB72)-like 1
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
TBKBP1 TBK1 binding protein 1
TBL2 transducin (beta)-like 2
TBX6 T-box 6
THY1 Thy-1 cell surface antigen
TP53I11 tumor protein p53 inducible protein 11
TP63 tumor protein p63
TP73-AS1 TP73 antisense RNA 1
TRAPPC9 trafficking protein particle complex 9
UBXN1 UBX domain protein 1
UPK2 uroplakin 2
VNN2 vanin 2
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZBTB17 zinc finger and BTB domain containing 17

decreased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ANP32A-IT1 ANP32A intronic transcript 1
ANXA2P1 annexin A2 pseudogene 1
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
ART1 ADP-ribosyltransferase 1
BDKRB1 bradykinin receptor B1
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CBS cystathionine-beta-synthase
CCDC186 coiled-coil domain containing 186
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CLDN1 claudin 1
CLDN8 claudin 8
CLSTN3 calsyntenin 3
COPZ2 coatomer protein complex, subunit zeta 2
CYTH3 cytohesin 3
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DHRS9 dehydrogenase/reductase (SDR family) member 9
DMTN dematin actin binding protein
DNM3 dynamin 3
DPF3 D4, zinc and double PHD fingers, family 3
EGLN3 egl-9 family hypoxia-inducible factor 3
ELAC1 elaC ribonuclease Z 1
EPN1 epsin 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FBXO31 F-box protein 31
FLJ21369 uncharacterized protein FLJ21369
GLB1L galactosidase, beta 1-like
GLCE glucuronic acid epimerase
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GRAMD1C GRAM domain containing 1C
GREB1L growth regulation by estrogen in breast cancer-like
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
GUSBP3 glucuronidase, beta pseudogene 3
HDAC7 histone deacetylase 7
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IL4R interleukin 4 receptor
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KIAA0319L KIAA0319-like
LIMD2 LIM domain containing 2
LINC00597 long intergenic non-protein coding RNA 597
LMO7 LIM domain 7
LOC157562 uncharacterized LOC157562
LOC257152 uncharacterized LOC257152
LYPD3 LY6/PLAUR domain containing 3
MAGEA12 melanoma antigen family A12
MAGEA5 melanoma antigen family A5
MAP3K7CL MAP3K7 C-terminal like
MCMBP minichromosome maintenance complex binding protein
MDM4 MDM4, p53 regulator
MEGF8 multiple EGF-like-domains 8
MILR1 mast cell immunoglobulin-like receptor 1
NDNF neuron-derived neurotrophic factor
NEO1 neogenin 1
OGDHL oxoglutarate dehydrogenase-like
OLFML2B olfactomedin-like 2B
ONECUT2 one cut homeobox 2
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OSMR oncostatin M receptor
PADI1 peptidyl arginine deiminase, type I
PCBP4 poly(rC) binding protein 4
PCOLCE procollagen C-endopeptidase enhancer
PIP prolactin-induced protein
PLCD1 phospholipase C, delta 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PSORS1C1 psoriasis susceptibility 1 candidate 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK6 protein tyrosine kinase 6
QPCTL glutaminyl-peptide cyclotransferase-like
RLN1 relaxin 1
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF39 ring finger protein 39
SALL2 spalt-like transcription factor 2
SAYSD1 SAYSVFN motif domain containing 1
SLAMF7 SLAM family member 7
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SLMO1 slowmo homolog 1 (Drosophila)
STAG3 stromal antigen 3
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TCEAL2 transcription elongation factor A (SII)-like 2
TET3 tet methylcytosine dioxygenase 3
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TINAGL1 tubulointerstitial nephritis antigen-like 1
TMEM74B transmembrane protein 74B
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TRAPPC13 trafficking protein particle complex 13
UBQLN4 ubiquilin 4
ZNF268 zinc finger protein 268
ZNF334 zinc finger protein 334
ZNF41 zinc finger protein 41
ZNF446 zinc finger protein 446
ZNF639 zinc finger protein 639
ZNF747 zinc finger protein 747