growth factor complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A protein complex that has growth factor activity. (Gene Ontology, GO_0036454)
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Genes

117 proteins co-occuring with the growth factor complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
IGFBP3 insulin-like growth factor binding protein 3 1.69543
IGF1 insulin-like growth factor 1 (somatomedin C) 1.37888
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 1.04364
IGFBP1 insulin-like growth factor binding protein 1 1.02713
IGFALS insulin-like growth factor binding protein, acid labile subunit 0.75453
GHR growth hormone receptor 0.627051
IGFBP5 insulin-like growth factor binding protein 5 0.581201
IGFBP6 insulin-like growth factor binding protein 6 0.491348
IGF2 insulin-like growth factor 2 0.404933
INS insulin 0.387494
IGFBP7 insulin-like growth factor binding protein 7 0.368026
PAPPA pregnancy-associated plasma protein A, pappalysin 1 0.358736
IGFBP4 insulin-like growth factor binding protein 4 0.354802
IGF1R insulin-like growth factor 1 receptor 0.324701
PAPPA2 pappalysin 2 0.268237
GH1 growth hormone 1 0.215296
PTH parathyroid hormone 0.210318
INSR insulin receptor 0.18796
LEP leptin 0.181227
SHBG sex hormone-binding globulin 0.172201
IGF2R insulin-like growth factor 2 receptor 0.170975
GHRH growth hormone releasing hormone 0.165932
TGFB1 transforming growth factor, beta 1 0.153671
FIGF c-fos induced growth factor (vascular endothelial growth factor D) 0.152802
HTRA1 HtrA serine peptidase 1 0.146545
CYR61 cysteine-rich, angiogenic inducer, 61 0.146085
IRS1 insulin receptor substrate 1 0.14602
IGFBPL1 insulin-like growth factor binding protein-like 1 0.145912
BGLAP bone gamma-carboxyglutamate (gla) protein 0.145241
KLK3 kallikrein-related peptidase 3 0.144483
CTGF connective tissue growth factor 0.143285
SST somatostatin 0.143007
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 0.142537
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 0.142418
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 0.142261
GHRL ghrelin/obestatin prepropeptide 0.141993
WISP3 WNT1 inducible signaling pathway protein 3 0.141971
FGF2 fibroblast growth factor 2 (basic) 0.141888
NOV nephroblastoma overexpressed 0.141818
ADAM12 ADAM metallopeptidase domain 12 0.141674
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 0.141559
GCG glucagon 0.141267
PAEP progestagen-associated endometrial protein 0.141205
SEBOX SEBOX homeobox 0.141104
MSTN myostatin 0.140917
LRP5 low density lipoprotein receptor-related protein 5 0.140868
FGF7 fibroblast growth factor 7 0.140657
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.140473
M6PR mannose-6-phosphate receptor (cation dependent) 0.140343
ESR1 estrogen receptor 1 0.140284
SIGLEC6 sialic acid binding Ig-like lectin 6 0.140075
WISP1 WNT1 inducible signaling pathway protein 1 0.140012
IL1B interleukin 1, beta 0.139987
LRRC70 leucine rich repeat containing 70 0.139606
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.139579
IL6 interleukin 6 0.139456
PRL prolactin 0.1394
MYOG myogenin (myogenic factor 4) 0.139106
IER5L immediate early response 5-like 0.138364
ALB albumin 0.138283
WISP2 WNT1 inducible signaling pathway protein 2 0.138192
ALPPL2 alkaline phosphatase, placental-like 2 0.138015
ALPL alkaline phosphatase, liver/bone/kidney 0.138006
ALPP alkaline phosphatase, placental 0.137998
IFI30 interferon, gamma-inducible protein 30 0.137964
RNASEH2A ribonuclease H2, subunit A 0.137869
ANGPTL5 angiopoietin-like 5 0.137729
TNF tumor necrosis factor 0.137424
POMC proopiomelanocortin 0.137323
FGF1 fibroblast growth factor 1 (acidic) 0.137323
IRS2 insulin receptor substrate 2 0.137258
ZNF84 zinc finger protein 84 0.137003
TGFB2 transforming growth factor, beta 2 0.13676
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen) 0.136581
CSH2 chorionic somatomammotropin hormone 2 0.136087
NME1 NME/NM23 nucleoside diphosphate kinase 1 0.135688
CRP C-reactive protein, pentraxin-related 0.135688
FSHR follicle stimulating hormone receptor 0.135432
TF transferrin 0.13533
TTR transthyretin 0.135295
FN1 fibronectin 1 0.135238
CSN1S1 casein alpha s1 0.134827
OBSL1 obscurin-like 1 0.134657
FST follistatin 0.134608
TRIP12 thyroid hormone receptor interactor 12 0.13417
KLHL21 kelch-like family member 21 0.133911
CCDC8 coiled-coil domain containing 8 0.133911
ORM1 orosomucoid 1 0.133871
ANGPT4 angiopoietin 4 0.133523
PLG plasminogen 0.133427
TP53 tumor protein p53 0.133386
BHMT betaine--homocysteine S-methyltransferase 0.133063
PGF placental growth factor 0.132949
BMP7 bone morphogenetic protein 7 0.132949
PGR progesterone receptor 0.132891
TIMP1 TIMP metallopeptidase inhibitor 1 0.132877
NPY4R neuropeptide Y receptor Y4 0.13279
GDF11 growth differentiation factor 11 0.132463
STAT5B signal transducer and activator of transcription 5B 0.132049
PDGFB platelet-derived growth factor beta polypeptide 0.131731
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans) 0.13137
CHRD chordin 0.131319
WT1 Wilms tumor 1 0.131133
COL1A2 collagen, type I, alpha 2 0.131047
OSBPL5 oxysterol binding protein-like 5 0.130944
IL15RA interleukin 15 receptor, alpha 0.130874
CUL7 cullin 7 0.130228
FBXO32 F-box protein 32 0.130117
MIIP migration and invasion inhibitory protein 0.129929
TG thyroglobulin 0.129602
KLK1 kallikrein 1 0.129444
PTEN phosphatase and tensin homolog 0.129204
YIPF1 Yip1 domain family, member 1 0.129164
IL1A interleukin 1, alpha 0.12873
EGFR epidermal growth factor receptor 0.128538
GBP5 guanylate binding protein 5 0.128452
CORIN corin, serine peptidase 0.1283