growth factor binding Gene Set

Dataset GO Molecular Function Annotations
Category structural or functional annotations
Type molecular function
Description Interacting selectively and non-covalently with any growth factor, proteins or polypeptides that stimulate a cell or organism to grow or proliferate. (Gene Ontology, GO_0019838)
External Link http://amigo.geneontology.org/amigo/term/GO:0019838
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Genes

118 genes performing the growth factor binding molecular function from the curated GO Molecular Function Annotations dataset.

Symbol Name
A2M alpha-2-macroglobulin
ACVR1 activin A receptor, type I
ACVR1B activin A receptor, type IB
ACVR1C activin A receptor, type IC
ACVR2A activin A receptor, type IIA
ACVR2B activin A receptor, type IIB
ACVRL1 activin A receptor type II-like 1
API5 apoptosis inhibitor 5
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
CD109 CD109 molecule
CD36 CD36 molecule (thrombospondin receptor)
CEP57 centrosomal protein 57kDa
COL1A1 collagen, type I, alpha 1
COL1A2 collagen, type I, alpha 2
COL2A1 collagen, type II, alpha 1
COL3A1 collagen, type III, alpha 1
COL4A1 collagen, type IV, alpha 1
COL5A1 collagen, type V, alpha 1
COL6A1 collagen, type VI, alpha 1
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CTGF connective tissue growth factor
CXCL13 chemokine (C-X-C motif) ligand 13
CYR61 cysteine-rich, angiogenic inducer, 61
EGFR epidermal growth factor receptor
ENG endoglin
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ESM1 endothelial cell-specific molecule 1
FGFBP1 fibroblast growth factor binding protein 1
FGFBP2 fibroblast growth factor binding protein 2
FGFBP3 fibroblast growth factor binding protein 3
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FGFR4 fibroblast growth factor receptor 4
FGFRL1 fibroblast growth factor receptor-like 1
FIBP fibroblast growth factor (acidic) intracellular binding protein
FLT1 fms-related tyrosine kinase 1
FLT4 fms-related tyrosine kinase 4
FURIN furin (paired basic amino acid cleaving enzyme)
GHRHR growth hormone releasing hormone receptor
GPC1 glypican 1
HAP1 huntingtin-associated protein 1
HAX1 HCLS1 associated protein X-1
HTRA1 HtrA serine peptidase 1
HTRA3 HtrA serine peptidase 3
HTRA4 HtrA serine peptidase 4
HYAL2 hyaluronoglucosaminidase 2
IGF1R insulin-like growth factor 1 receptor
IGF2R insulin-like growth factor 2 receptor
IGFALS insulin-like growth factor binding protein, acid labile subunit
IGFBP1 insulin-like growth factor binding protein 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP3 insulin-like growth factor binding protein 3
IGFBP4 insulin-like growth factor binding protein 4
IGFBP5 insulin-like growth factor binding protein 5
IGFBP6 insulin-like growth factor binding protein 6
IGFBP7 insulin-like growth factor binding protein 7
IGFBPL1 insulin-like growth factor binding protein-like 1
IL10RA interleukin 10 receptor, alpha
IL1RAPL1 interleukin 1 receptor accessory protein-like 1
IL1RN interleukin 1 receptor antagonist
IL2RA interleukin 2 receptor, alpha
IL2RB interleukin 2 receptor, beta
IL2RG interleukin 2 receptor, gamma
IL36RN interleukin 36 receptor antagonist
IL6R interleukin 6 receptor
IL6ST interleukin 6 signal transducer
IL9R interleukin 9 receptor
INSR insulin receptor
ITGAV integrin, alpha V
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KDR kinase insert domain receptor
KL klotho
KLB klotho beta
LIFR leukemia inhibitory factor receptor alpha
LTBP1 latent transforming growth factor beta binding protein 1
LTBP2 latent transforming growth factor beta binding protein 2
LTBP3 latent transforming growth factor beta binding protein 3
LTBP4 latent transforming growth factor beta binding protein 4
NGFR nerve growth factor receptor
NKD2 naked cuticle homolog 2 (Drosophila)
NOV nephroblastoma overexpressed
NRD1 nardilysin (N-arginine dibasic convertase)
NRP1 neuropilin 1
NRP2 neuropilin 2
NTF3 neurotrophin 3
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
OSMR oncostatin M receptor
PCSK6 proprotein convertase subtilisin/kexin type 6
PDGFA platelet-derived growth factor alpha polypeptide
PDGFB platelet-derived growth factor beta polypeptide
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PXDN peroxidasin
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RPS19 ribosomal protein S19
RPS2 ribosomal protein S2
S100A13 S100 calcium binding protein A13
SCN5A sodium channel, voltage gated, type V alpha subunit
SDCBP syndecan binding protein (syntenin)
SEC61B Sec61 beta subunit
SORT1 sortilin 1
SRPX2 sushi-repeat containing protein, X-linked 2
TEK TEK tyrosine kinase, endothelial
TGFB3 transforming growth factor, beta 3
TGFBR1 transforming growth factor, beta receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGFBR3 transforming growth factor, beta receptor III
THBS1 thrombospondin 1
TRIM16 tripartite motif containing 16
VASN vasorin
WISP1 WNT1 inducible signaling pathway protein 1
WISP2 WNT1 inducible signaling pathway protein 2
WISP3 WNT1 inducible signaling pathway protein 3