griseofulvin-7363 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the griseofulvin-7363 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AMACR alpha-methylacyl-CoA racemase
ANXA10 annexin A10
ARHGAP35 Rho GTPase activating protein 35
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BCL2 B-cell CLL/lymphoma 2
BICD1 bicaudal D homolog 1 (Drosophila)
BIN1 bridging integrator 1
BTBD7 BTB (POZ) domain containing 7
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CADPS2 Ca++-dependent secretion activator 2
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP5 caspase 5, apoptosis-related cysteine peptidase
CCL21 chemokine (C-C motif) ligand 21
COL10A1 collagen, type X, alpha 1
CSDC2 cold shock domain containing C2, RNA binding
CSF1 colony stimulating factor 1 (macrophage)
CYSLTR1 cysteinyl leukotriene receptor 1
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DNAAF1 dynein, axonemal, assembly factor 1
DRD2 dopamine receptor D2
ELL elongation factor RNA polymerase II
EMID1 EMI domain containing 1
FAM120C family with sequence similarity 120C
FAM182B family with sequence similarity 182, member B
FBLN1 fibulin 1
FUZ fuzzy planar cell polarity protein
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5
GAS8 growth arrest-specific 8
GATA2 GATA binding protein 2
GLI2 GLI family zinc finger 2
HAO2 hydroxyacid oxidase 2 (long chain)
HBB hemoglobin, beta
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HOXA4 homeobox A4
HOXB3 homeobox B3
HRK harakiri, BCL2 interacting protein
HSPA12A heat shock 70kDa protein 12A
IL12A interleukin 12A
IL17RA interleukin 17 receptor A
INPP5J inositol polyphosphate-5-phosphatase J
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1
KCNK12 potassium channel, two pore domain subfamily K, member 12
KIF5C kinesin family member 5C
KLK7 kallikrein-related peptidase 7
KRT17 keratin 17, type I
LAX1 lymphocyte transmembrane adaptor 1
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LMNA lamin A/C
LRRK1 leucine-rich repeat kinase 1
MAP2K7 mitogen-activated protein kinase kinase 7
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MTRF1L mitochondrial translational release factor 1-like
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NNMT nicotinamide N-methyltransferase
NPFFR1 neuropeptide FF receptor 1
NR5A2 nuclear receptor subfamily 5, group A, member 2
NRP2 neuropilin 2
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PEX3 peroxisomal biogenesis factor 3
PEX6 peroxisomal biogenesis factor 6
PGM5 phosphoglucomutase 5
PHLDB1 pleckstrin homology-like domain, family B, member 1
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PICK1 protein interacting with PRKCA 1
PLCE1 phospholipase C, epsilon 1
PLK4 polo-like kinase 4
PLN phospholamban
PMP2 peripheral myelin protein 2
PODNL1 podocan-like 1
POM121 POM121 transmembrane nucleoporin
POMT2 protein-O-mannosyltransferase 2
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PTCRA pre T-cell antigen receptor alpha
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAB36 RAB36, member RAS oncogene family
RIBC2 RIB43A domain with coiled-coils 2
RNF39 ring finger protein 39
RUNX3 runt-related transcription factor 3
RYR2 ryanodine receptor 2 (cardiac)
SDC2 syndecan 2
SDS serine dehydratase
SEC14L2 SEC14-like 2 (S. cerevisiae)
SFTPB surfactant protein B
SH3BP2 SH3-domain binding protein 2
SKIL SKI-like proto-oncogene
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLCO3A1 solute carrier organic anion transporter family, member 3A1
SMC1A structural maintenance of chromosomes 1A
SPX spexin hormone
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TAOK1 TAO kinase 1
TAT tyrosine aminotransferase
TGFB2 transforming growth factor, beta 2
TNK1 tyrosine kinase, non-receptor, 1
TRIM3 tripartite motif containing 3
TRIM31 tripartite motif containing 31
ZNF768 zinc finger protein 768

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ACKR3 atypical chemokine receptor 3
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
AFAP1 actin filament associated protein 1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
APH1B APH1B gamma secretase subunit
BAG4 BCL2-associated athanogene 4
BAK1 BCL2-antagonist/killer 1
BANK1 B-cell scaffold protein with ankyrin repeats 1
BBS10 Bardet-Biedl syndrome 10
BIRC3 baculoviral IAP repeat containing 3
BOLA1 bolA family member 1
C19ORF54 chromosome 19 open reading frame 54
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CAMTA2 calmodulin binding transcription activator 2
CASZ1 castor zinc finger 1
CBX4 chromobox homolog 4
CCDC69 coiled-coil domain containing 69
CDH7 cadherin 7, type 2
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CPA4 carboxypeptidase A4
CTBS chitobiase, di-N-acetyl-
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DCAF17 DDB1 and CUL4 associated factor 17
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DOLPP1 dolichyldiphosphatase 1
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
ELP6 elongator acetyltransferase complex subunit 6
ETAA1 Ewing tumor-associated antigen 1
FAM114A2 family with sequence similarity 114, member A2
FAM160B2 family with sequence similarity 160, member B2
FAM193B family with sequence similarity 193, member B
FAM86C1 family with sequence similarity 86, member C1
FBXW4 F-box and WD repeat domain containing 4
FHOD1 formin homology 2 domain containing 1
GAB2 GRB2-associated binding protein 2
GJC1 gap junction protein, gamma 1, 45kDa
GLI3 GLI family zinc finger 3
GUF1 GUF1 GTPase homolog (S. cerevisiae)
HMBS hydroxymethylbilane synthase
IFT46 intraflagellar transport 46
INF2 inverted formin, FH2 and WH2 domain containing
KATNBL1 katanin p80 subunit B-like 1
KIAA0513 KIAA0513
KIAA1549L KIAA1549-like
LINC00339 long intergenic non-protein coding RNA 339
MANEA mannosidase, endo-alpha
MCRS1 microspherule protein 1
MT1M metallothionein 1M
MTMR11 myotubularin related protein 11
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NOL12 nucleolar protein 12
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
PARP16 poly (ADP-ribose) polymerase family, member 16
PEG3 paternally expressed 3
PLA2G15 phospholipase A2, group XV
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PLSCR4 phospholipid scramblase 4
PPP1R9A protein phosphatase 1, regulatory subunit 9A
RAB17 RAB17, member RAS oncogene family
REEP4 receptor accessory protein 4
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF25 ring finger protein 25
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RPP25 ribonuclease P/MRP 25kDa subunit
RUNX1-IT1 RUNX1 intronic transcript 1
SCARA3 scavenger receptor class A, member 3
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SETBP1 SET binding protein 1
SETD6 SET domain containing 6
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1
SLITRK5 SLIT and NTRK-like family, member 5
SMAD7 SMAD family member 7
SP140L SP140 nuclear body protein-like
SSNA1 Sjogren syndrome nuclear autoantigen 1
TBX19 T-box 19
TFB1M transcription factor B1, mitochondrial
TMEM187 transmembrane protein 187
TMEM2 transmembrane protein 2
TMEM254 transmembrane protein 254
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TPCN1 two pore segment channel 1
TRABD TraB domain containing
TRAF5 TNF receptor-associated factor 5
USP6 ubiquitin specific peptidase 6
ZBTB48 zinc finger and BTB domain containing 48
ZNF204P zinc finger protein 204, pseudogene
ZNF264 zinc finger protein 264
ZNF671 zinc finger protein 671
ZNF675 zinc finger protein 675
ZNF8 zinc finger protein 8
ZNF83 zinc finger protein 83