granulation tissue Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description Highly vascularized tissue that replaces the initial fibrin clot in a wound. Vascularization is by ingrowth of capillary endothelium from the surrounding vasculature. The tissue is also rich in fibroblasts (that will eventually produce the fibrous tissue) and leucocytes. (BRENDA Tissue and Enzyme Source Ontology, BTO_0003257)
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Genes

207 proteins co-occuring with the tissue granulation tissue in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
FGF2 fibroblast growth factor 2 (basic) 1.9055
FN1 fibronectin 1 1.78437
TGFB1 transforming growth factor, beta 1 1.67805
DCXR dicarbonyl/L-xylulose reductase 1.51759
PDGFB platelet-derived growth factor beta polypeptide 1.4589
HBA1 hemoglobin, alpha 1 1.30658
HBA2 hemoglobin, alpha 2 1.29175
VEGFA vascular endothelial growth factor A 1.23896
MMP1 matrix metallopeptidase 1 1.19089
FGF7 fibroblast growth factor 7 1.17225
MMP3 matrix metallopeptidase 3 1.16648
LAMA3 laminin, alpha 3 1.16293
CTGF connective tissue growth factor 1.16116
MMP2 matrix metallopeptidase 2 1.14786
CD68 CD68 molecule 1.08015
COL1A2 collagen, type I, alpha 2 1.07265
TNC tenascin C 1.04005
MMP9 matrix metallopeptidase 9 1.02162
EDA ectodysplasin A 0.992379
F8 coagulation factor VIII, procoagulant component 0.974583
TNF tumor necrosis factor 0.972417
CD34 CD34 molecule 0.963335
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) 0.951254
PCNA proliferating cell nuclear antigen 0.943075
MMP13 matrix metallopeptidase 13 0.942645
ALB albumin 0.923339
TIMP1 TIMP metallopeptidase inhibitor 1 0.922483
IGF1 insulin-like growth factor 1 (somatomedin C) 0.87782
DLX2 distal-less homeobox 2 0.86642
IL1B interleukin 1, beta 0.86347
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.832804
PID1 phosphotyrosine interaction domain containing 1 0.828197
PLG plasminogen 0.793959
MMP8 matrix metallopeptidase 8 0.79146
PLAU plasminogen activator, urokinase 0.780232
FGF1 fibroblast growth factor 1 (acidic) 0.778155
VWF von Willebrand factor 0.765296
IL6 interleukin 6 0.7595
TGFB2 transforming growth factor, beta 2 0.754124
COL3A1 collagen, type III, alpha 1 0.752057
GLB1 galactosidase, beta 1 0.747515
CCL2 chemokine (C-C motif) ligand 2 0.742976
CD44 CD44 molecule (Indian blood group) 0.735971
ACPP acid phosphatase, prostate 0.71501
SPP1 secreted phosphoprotein 1 0.70845
FTSJ3 FtsJ homolog 3 (E. coli) 0.706402
NT5M 5',3'-nucleotidase, mitochondrial 0.698216
DCN decorin 0.679433
GJB6 gap junction protein, beta 6, 30kDa 0.674135
SMAD2 SMAD family member 2 0.651777
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 0.651371
ALPPL2 alkaline phosphatase, placental-like 2 0.649749
BGN biglycan 0.648938
ALPL alkaline phosphatase, liver/bone/kidney 0.648938
BAG6 BCL2-associated athanogene 6 0.648532
ALPP alkaline phosphatase, placental 0.648127
CYR61 cysteine-rich, angiogenic inducer, 61 0.637999
TGFB3 transforming growth factor, beta 3 0.635167
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.629506
SOD2 superoxide dismutase 2, mitochondrial 0.618603
TAC1 tachykinin, precursor 1 0.614571
FMOD fibromodulin 0.606916
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.603295
KRT14 keratin 14, type I 0.602088
COL9A1 collagen, type IX, alpha 1 0.600077
CMA1 chymase 1, mast cell 0.600077
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) 0.598871
TIMP2 TIMP metallopeptidase inhibitor 2 0.595656
VEGFC vascular endothelial growth factor C 0.588832
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.588832
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 0.584022
COMP cartilage oligomeric matrix protein 0.58282
MDS2 myelodysplastic syndrome 2 translocation associated 0.58282
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.573217
SMAD3 SMAD family member 3 0.568025
CAT catalase 0.565631
OGFR opioid growth factor receptor 0.563238
IL1A interleukin 1, alpha 0.556865
TRIM71 tripartite motif containing 71, E3 ubiquitin protein ligase 0.556467
FGFR1OP2 FGFR1 oncogene partner 2 0.55249
SEBOX SEBOX homeobox 0.551298
SDC2 syndecan 2 0.550106
CCDC130 coiled-coil domain containing 130 0.547724
COL1A1 collagen, type I, alpha 1 0.545342
MPO myeloperoxidase 0.539
CXCL8 chemokine (C-X-C motif) ligand 8 0.534251
BMP2 bone morphogenetic protein 2 0.526744
MLPH melanophilin 0.516497
TSPO translocator protein (18kDa) 0.513743
WISP3 WNT1 inducible signaling pathway protein 3 0.50471
FANCB Fanconi anemia, complementation group B 0.490229
SNTG1 syntrophin, gamma 1 0.489057
LOX lysyl oxidase 0.489057
CALCA calcitonin-related polypeptide alpha 0.478534
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.474258
LAMB3 laminin, beta 3 0.468048
SRF serum response factor (c-fos serum response element-binding transcription factor) 0.4634
SMAD7 SMAD family member 7 0.461078
SMAD9 SMAD family member 9 0.456828
THBS1 thrombospondin 1 0.452969
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 0.451428
INS insulin 0.449886
RIMS2 regulating synaptic membrane exocytosis 2 0.446422
MMP7 matrix metallopeptidase 7 0.443347
WISP2 WNT1 inducible signaling pathway protein 2 0.440658
FBLN5 fibulin 5 0.433757
KDR kinase insert domain receptor 0.433757
ITGAV integrin, alpha V 0.429547
CRP C-reactive protein, pentraxin-related 0.426872
NOV nephroblastoma overexpressed 0.425344
NGF nerve growth factor (beta polypeptide) 0.423436
CNN3 calponin 3, acidic 0.420385
EDN1 endothelin 1 0.413912
MMP10 matrix metallopeptidase 10 0.413151
COL18A1 collagen, type XVIII, alpha 1 0.408592
PDGFA platelet-derived growth factor alpha polypeptide 0.407453
CTSG cathepsin G 0.406694
CCL13 chemokine (C-C motif) ligand 13 0.40025
FBRS fibrosin 0.396465
COL7A1 collagen, type VII, alpha 1 0.391176
POU6F2 POU class 6 homeobox 2 0.390799
WISP1 WNT1 inducible signaling pathway protein 1 0.389666
KRT10 keratin 10, type I 0.389289
SDC4 syndecan 4 0.385143
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) 0.381755
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.381379
FST follistatin 0.366754
SIL1 SIL1 nucleotide exchange factor 0.364886
SLC35G5 solute carrier family 35, member G5 0.360782
HBG1 hemoglobin, gamma A 0.360036
SDC1 syndecan 1 0.354455
L1CAM L1 cell adhesion molecule 0.352227
TP53 tumor protein p53 0.346298
IL10 interleukin 10 0.344079
RNASEH2A ribonuclease H2, subunit A 0.339282
DNTT DNA nucleotidylexotransferase 0.339282
SP7 Sp7 transcription factor 0.334498
TIMP3 TIMP metallopeptidase inhibitor 3 0.333028
USP4 ubiquitin specific peptidase 4 (proto-oncogene) 0.333028
CD4 CD4 molecule 0.33046
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.329361
IBSP integrin-binding sialoprotein 0.327896
BGLAP bone gamma-carboxyglutamate (gla) protein 0.325701
FLT4 fms-related tyrosine kinase 4 0.323144
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.322779
SETD1A SET domain containing 1A 0.320227
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 0.318407
GJA1 gap junction protein, alpha 1, 43kDa 0.317679
MCOLN1 mucolipin 1 0.316588
PDLIM7 PDZ and LIM domain 7 (enigma) 0.315135
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 0.315135
LYZ lysozyme 0.314046
CLNK cytokine-dependent hematopoietic cell linker 0.31332
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.308251
CTSD cathepsin D 0.305361
THBS2 thrombospondin 2 0.305361
EFNB2 ephrin-B2 0.302118
S100A7 S100 calcium binding protein A7 0.300679
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.299601
FGFR1 fibroblast growth factor receptor 1 0.298524
CTSS cathepsin S 0.29673
IDS iduronate 2-sulfatase 0.294581
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) 0.294223
FGFR2 fibroblast growth factor receptor 2 0.293866
CLEC3B C-type lectin domain family 3, member B 0.290295
LGALS2 lectin, galactoside-binding, soluble, 2 0.290295
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 0.28887
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 0.286736
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 0.285671
VCL vinculin 0.285671
PEX2 peroxisomal biogenesis factor 2 0.279659
CALR calreticulin 0.278251
TEAD4 TEA domain family member 4 0.273346
IVD isovaleryl-CoA dehydrogenase 0.266757
ILK integrin-linked kinase 0.262645
KRT16 keratin 16, type I 0.262645
BAX BCL2-associated X protein 0.261284
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.260267
SFRP2 secreted frizzled-related protein 2 0.258917
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.250953
KNG1 kininogen 1 0.249977
THBS3 thrombospondin 3 0.249977
CXCL10 chemokine (C-X-C motif) ligand 10 0.249653
PDCL2 phosducin-like 2 0.245807
ELANE elastase, neutrophil expressed 0.24052
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.240216
CTHRC1 collagen triple helix repeat containing 1 0.239913
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.23961
HOXD3 homeobox D3 0.239307
FGF10 fibroblast growth factor 10 0.239007
CSN1S1 casein alpha s1 0.238406
A1BG alpha-1-B glycoprotein 0.236921
HSPG2 heparan sulfate proteoglycan 2 0.232881
CXCR1 chemokine (C-X-C motif) receptor 1 0.23011
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 0.229568
THY1 Thy-1 cell surface antigen 0.229032
DGKZ diacylglycerol kinase, zeta 0.22797
CYFIP2 cytoplasmic FMR1 interacting protein 2 0.226926
GH1 growth hormone 1 0.226411
WDFY2 WD repeat and FYVE domain containing 2 0.222699
ADAM33 ADAM metallopeptidase domain 33 0.221755
PDXK pyridoxal (pyridoxine, vitamin B6) kinase 0.221755
FERMT1 fermitin family member 1 0.220378
GPX5 glutathione peroxidase 5 0.216933
FAP fibroblast activation protein, alpha 0.216325
GPX4 glutathione peroxidase 4 0.215147
ARPP21 cAMP-regulated phosphoprotein, 21kDa 0.213833