glycocholic acid-6716 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the glycocholic acid-6716 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ADAM20 ADAM metallopeptidase domain 20
ADCY2 adenylate cyclase 2 (brain)
ADGRL3 adhesion G protein-coupled receptor L3
AKAP13 A kinase (PRKA) anchor protein 13
AQP4 aquaporin 4
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ASIC2 acid sensing (proton gated) ion channel 2
BEGAIN brain-enriched guanylate kinase-associated
C7ORF69 chromosome 7 open reading frame 69
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CASS4 Cas scaffolding protein family member 4
CHRM5 cholinergic receptor, muscarinic 5
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CISH cytokine inducible SH2-containing protein
CLMN calmin (calponin-like, transmembrane)
COL5A1 collagen, type V, alpha 1
CPN2 carboxypeptidase N, polypeptide 2
CTSF cathepsin F
CXXC4 CXXC finger protein 4
DCLK2 doublecortin-like kinase 2
DPEP2 dipeptidase 2
DSCAM Down syndrome cell adhesion molecule
EFR3B EFR3 homolog B (S. cerevisiae)
EML2 echinoderm microtubule associated protein like 2
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FBXO41 F-box protein 41
FGFR1 fibroblast growth factor receptor 1
FOXO4 forkhead box O4
GH1 growth hormone 1
GLP1R glucagon-like peptide 1 receptor
GLRA3 glycine receptor, alpha 3
GRIK5 glutamate receptor, ionotropic, kainate 5
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HEMK1 HemK methyltransferase family member 1
HLA-DOA major histocompatibility complex, class II, DO alpha
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
IBSP integrin-binding sialoprotein
IZUMO4 IZUMO family member 4
JAK3 Janus kinase 3
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2
KIF25-AS1 KIF25 antisense RNA 1
KRT14 keratin 14, type I
LIMD1 LIM domains containing 1
LOC284244 uncharacterized LOC284244
MAG myelin associated glycoprotein
MBD2 methyl-CpG binding domain protein 2
N4BP2L1 NEDD4 binding protein 2-like 1
ONECUT2 one cut homeobox 2
OR1G1 olfactory receptor, family 1, subfamily G, member 1
PADI1 peptidyl arginine deiminase, type I
PAX8 paired box 8
PCDHA5 protocadherin alpha 5
PCDHGA10 protocadherin gamma subfamily A, 10
PDE11A phosphodiesterase 11A
PDE4DIP phosphodiesterase 4D interacting protein
PDLIM3 PDZ and LIM domain 3
PHF14 PHD finger protein 14
PKNOX2 PBX/knotted 1 homeobox 2
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A
PQBP1 polyglutamine binding protein 1
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PYY peptide YY
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
REPS1 RALBP1 associated Eps domain containing 1
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RNLS renalase, FAD-dependent amine oxidase
RPH3AL rabphilin 3A-like (without C2 domains)
RPL14 ribosomal protein L14
RUNX1 runt-related transcription factor 1
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SARDH sarcosine dehydrogenase
SCRT1 scratch family zinc finger 1
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SLC26A1 solute carrier family 26 (anion exchanger), member 1
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SOX21 SRY (sex determining region Y)-box 21
SUGP1 SURP and G patch domain containing 1
THTPA thiamine triphosphatase
TIMP4 TIMP metallopeptidase inhibitor 4
TLX2 T-cell leukemia homeobox 2
TMEM140 transmembrane protein 140
TRAT1 T cell receptor associated transmembrane adaptor 1
TRPM3 transient receptor potential cation channel, subfamily M, member 3
TTLL3 tubulin tyrosine ligase-like family member 3
UBE2I ubiquitin-conjugating enzyme E2I
UST uronyl-2-sulfotransferase
VASH1 vasohibin 1
VCX2 variable charge, X-linked 2
VLDLR very low density lipoprotein receptor
WDR78 WD repeat domain 78
WT1-AS WT1 antisense RNA
ZFP30 ZFP30 zinc finger protein

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ACAD8 acyl-CoA dehydrogenase family, member 8
ADCY6 adenylate cyclase 6
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ALDH18A1 aldehyde dehydrogenase 18 family, member A1
AP1AR adaptor-related protein complex 1 associated regulatory protein
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ARHGAP10 Rho GTPase activating protein 10
ATAD5 ATPase family, AAA domain containing 5
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
C19ORF40 chromosome 19 open reading frame 40
C8ORF60 chromosome 8 open reading frame 60
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCNJL cyclin J-like
CCP110 centriolar coiled coil protein 110kDa
CEL carboxyl ester lipase
CENPJ centromere protein J
CHM choroideremia (Rab escort protein 1)
CUEDC1 CUE domain containing 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7
DOCK1 dedicator of cytokinesis 1
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ERMP1 endoplasmic reticulum metallopeptidase 1
FABP4 fatty acid binding protein 4, adipocyte
FAM204A family with sequence similarity 204, member A
FER fer (fps/fes related) tyrosine kinase
FNTB farnesyltransferase, CAAX box, beta
GJC1 gap junction protein, gamma 1, 45kDa
GPNMB glycoprotein (transmembrane) nmb
GTF2I general transcription factor IIi
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
H2BFS H2B histone family, member S (pseudogene)
HELZ helicase with zinc finger
HIST1H2AM histone cluster 1, H2am
HMOX1 heme oxygenase 1
IFI6 interferon, alpha-inducible protein 6
IPO8 importin 8
IQCG IQ motif containing G
IRAK4 interleukin-1 receptor-associated kinase 4
KRT8P12 keratin 8 pseudogene 12
LRRC37A3 leucine rich repeat containing 37, member A3
LRRC61 leucine rich repeat containing 61
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LYPD3 LY6/PLAUR domain containing 3
MANBA mannosidase, beta A, lysosomal
MBTD1 mbt domain containing 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
MCC mutated in colorectal cancers
MED18 mediator complex subunit 18
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MMP13 matrix metallopeptidase 13
MOCS3 molybdenum cofactor synthesis 3
MPDU1 mannose-P-dolichol utilization defect 1
MRPS18C mitochondrial ribosomal protein S18C
NDP Norrie disease (pseudoglioma)
NT5M 5',3'-nucleotidase, mitochondrial
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PARPBP PARP1 binding protein
PDE12 phosphodiesterase 12
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
POLL polymerase (DNA directed), lambda
POLR2F polymerase (RNA) II (DNA directed) polypeptide F
PRKX protein kinase, X-linked
RABEP1 rabaptin, RAB GTPase binding effector protein 1
S100A3 S100 calcium binding protein A3
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SLC4A3 solute carrier family 4 (anion exchanger), member 3
SMAD7 SMAD family member 7
SPAG7 sperm associated antigen 7
SPEG SPEG complex locus
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STK16 serine/threonine kinase 16
THBS3 thrombospondin 3
THOC6 THO complex 6
THRAP3 thyroid hormone receptor associated protein 3
TMEM156 transmembrane protein 156
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TSPAN1 tetraspanin 1
TXLNG taxilin gamma
ULBP2 UL16 binding protein 2
USP19 ubiquitin specific peptidase 19
UTRN utrophin
WDR62 WD repeat domain 62
ZBTB6 zinc finger and BTB domain containing 6
ZMAT5 zinc finger, matrin-type 5
ZNF215 zinc finger protein 215
ZNF510 zinc finger protein 510