glycocholic acid-5316 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the glycocholic acid-5316 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AIF1 allograft inflammatory factor 1
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATRN attractin
AVL9 AVL9 homolog (S. cerevisiase)
BBS9 Bardet-Biedl syndrome 9
BCL9 B-cell CLL/lymphoma 9
BMP4 bone morphogenetic protein 4
BTD biotinidase
C10ORF95 chromosome 10 open reading frame 95
CAMK1 calcium/calmodulin-dependent protein kinase I
CDC14A cell division cycle 14A
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CFLAR CASP8 and FADD-like apoptosis regulator
CHKA choline kinase alpha
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CLCN7 chloride channel, voltage-sensitive 7
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DACH1 dachshund family transcription factor 1
DCAF15 DDB1 and CUL4 associated factor 15
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DOCK4 dedicator of cytokinesis 4
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
F2R coagulation factor II (thrombin) receptor
F3 coagulation factor III (thromboplastin, tissue factor)
FBLN1 fibulin 1
FCHO1 FCH domain only 1
FGF23 fibroblast growth factor 23
FRS2 fibroblast growth factor receptor substrate 2
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GPATCH3 G patch domain containing 3
GTPBP2 GTP binding protein 2
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IFI35 interferon-induced protein 35
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFITM1 interferon induced transmembrane protein 1
IFNAR2 interferon (alpha, beta and omega) receptor 2
ISG15 ISG15 ubiquitin-like modifier
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAPK7 mitogen-activated protein kinase 7
MARK4 MAP/microtubule affinity-regulating kinase 4
MBD3 methyl-CpG binding domain protein 3
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MXD3 MAX dimerization protein 3
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NXT2 nuclear transport factor 2-like export factor 2
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
PACS1 phosphofurin acidic cluster sorting protein 1
PBX2 pre-B-cell leukemia homeobox 2
PC pyruvate carboxylase
PDE4DIP phosphodiesterase 4D interacting protein
PIAS4 protein inhibitor of activated STAT, 4
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PLEKHO1 pleckstrin homology domain containing, family O member 1
PLK4 polo-like kinase 4
POGZ pogo transposable element with ZNF domain
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PTCH1 patched 1
RAD51B RAD51 paralog B
RNF41 ring finger protein 41, E3 ubiquitin protein ligase
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
S100A4 S100 calcium binding protein A4
S100A8 S100 calcium binding protein A8
SCAND2P SCAN domain containing 2 pseudogene
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SH2D4A SH2 domain containing 4A
SH3BP2 SH3-domain binding protein 2
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC48A1 solute carrier family 48 (heme transporter), member 1
SUGP1 SURP and G patch domain containing 1
SULT4A1 sulfotransferase family 4A, member 1
TAOK1 TAO kinase 1
TCP11L1 t-complex 11, testis-specific-like 1
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TRIM21 tripartite motif containing 21
TRIM25 tripartite motif containing 25
TSPAN1 tetraspanin 1
TTC9 tetratricopeptide repeat domain 9
UNC45A unc-45 homolog A (C. elegans)
UPK3B uroplakin 3B
VAV2 vav 2 guanine nucleotide exchange factor
VIPR2 vasoactive intestinal peptide receptor 2
WWOX WW domain containing oxidoreductase
ZCCHC24 zinc finger, CCHC domain containing 24
ZNF43 zinc finger protein 43
ZNF551 zinc finger protein 551
ZNF606 zinc finger protein 606
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AP1B1 adaptor-related protein complex 1, beta 1 subunit
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
AP3M2 adaptor-related protein complex 3, mu 2 subunit
AP4M1 adaptor-related protein complex 4, mu 1 subunit
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
BAX BCL2-associated X protein
BBC3 BCL2 binding component 3
BHLHB9 basic helix-loop-helix domain containing, class B, 9
BTF3P12 basic transcription factor 3 pseudogene 12
CAMTA2 calmodulin binding transcription activator 2
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CDK3 cyclin-dependent kinase 3
CEP72 centrosomal protein 72kDa
CHST10 carbohydrate sulfotransferase 10
CLCN2 chloride channel, voltage-sensitive 2
CRYBG3 beta-gamma crystallin domain containing 3
CTNNBIP1 catenin, beta interacting protein 1
DDIT3 DNA-damage-inducible transcript 3
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DUSP5 dual specificity phosphatase 5
EAF2 ELL associated factor 2
ELOVL4 ELOVL fatty acid elongase 4
EPPK1 epiplakin 1
EYA2 EYA transcriptional coactivator and phosphatase 2
FAM118A family with sequence similarity 118, member A
FAM63A family with sequence similarity 63, member A
FBRS fibrosin
FGD6 FYVE, RhoGEF and PH domain containing 6
GLS2 glutaminase 2 (liver, mitochondrial)
GSTM1 glutathione S-transferase mu 1
HIRA histone cell cycle regulator
HIST1H2AJ histone cluster 1, H2aj
HMGB3P1 high mobility group box 3 pseudogene 1
HSPA2 heat shock 70kDa protein 2
HTRA1 HtrA serine peptidase 1
IPP intracisternal A particle-promoted polypeptide
KIAA0513 KIAA0513
KIF13B kinesin family member 13B
KIF1B kinesin family member 1B
KIFC1 kinesin family member C1
KLF11 Kruppel-like factor 11
LMNB1 lamin B1
LOC390998 ribosomal protein L10 pseudogene
LOC642236 FSHD region gene 1 pseudogene
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
LRP3 low density lipoprotein receptor-related protein 3
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MEIS2 Meis homeobox 2
METTL2B methyltransferase like 2B
MKNK2 MAP kinase interacting serine/threonine kinase 2
MXRA7 matrix-remodelling associated 7
MYO19 myosin XIX
NABP2 nucleic acid binding protein 2
NBEAL2 neurobeachin-like 2
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2
PELI1 pellino E3 ubiquitin protein ligase 1
PEX26 peroxisomal biogenesis factor 26
PGP phosphoglycolate phosphatase
PHKA1 phosphorylase kinase, alpha 1 (muscle)
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PPT2 palmitoyl-protein thioesterase 2
PRICKLE3 prickle homolog 3 (Drosophila)
PRSS22 protease, serine, 22
PTK6 protein tyrosine kinase 6
PTOV1 prostate tumor overexpressed 1
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RIN2 Ras and Rab interactor 2
RSAD1 radical S-adenosyl methionine domain containing 1
SAV1 salvador family WW domain containing protein 1
SCMH1 sex comb on midleg homolog 1 (Drosophila)
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SLC25A40 solute carrier family 25, member 40
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SMA4 glucuronidase, beta pseudogene
SNIP1 Smad nuclear interacting protein 1
SPINK4 serine peptidase inhibitor, Kazal type 4
SQRDL sulfide quinone reductase-like (yeast)
SUSD6 sushi domain containing 6
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TGFBI transforming growth factor, beta-induced, 68kDa
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TSKU tsukushi, small leucine rich proteoglycan
TTC26 tetratricopeptide repeat domain 26
UBQLN4 ubiquilin 4
VWA1 von Willebrand factor A domain containing 1
ZC3H12A zinc finger CCCH-type containing 12A
ZNF282 zinc finger protein 282
ZNF668 zinc finger protein 668
ZNF7 zinc finger protein 7
ZNF768 zinc finger protein 768
ZNF816 zinc finger protein 816