glycocholic acid-3315 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the glycocholic acid-3315 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
AHI1 Abelson helper integration site 1
AHR aryl hydrocarbon receptor
ALMS1 Alstrom syndrome protein 1
ARC activity-regulated cytoskeleton-associated protein
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATM ATM serine/threonine kinase
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
ATXN7L3B ataxin 7-like 3B
BBS9 Bardet-Biedl syndrome 9
BCAM basal cell adhesion molecule (Lutheran blood group)
BET1L Bet1 golgi vesicular membrane trafficking protein-like
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CCNT2 cyclin T2
CEL carboxyl ester lipase
CFLAR CASP8 and FADD-like apoptosis regulator
CLCA2 chloride channel accessory 2
CNTNAP1 contactin associated protein 1
COPS7B COP9 signalosome subunit 7B
CRAT carnitine O-acetyltransferase
CSF1R colony stimulating factor 1 receptor
CXADR coxsackie virus and adenovirus receptor
DAPK2 death-associated protein kinase 2
DFNB31 deafness, autosomal recessive 31
DGCR8 DGCR8 microprocessor complex subunit
DKK3 dickkopf WNT signaling pathway inhibitor 3
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
FCMR Fc fragment of IgM receptor
FOXN3 forkhead box N3
FSCN1 fascin actin-bundling protein 1
GK2 glycerol kinase 2
GM2A GM2 ganglioside activator
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GOLGA8A golgin A8 family, member A
GREB1 growth regulation by estrogen in breast cancer 1
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H3A histone cluster 1, H3a
HIST1H4F histone cluster 1, H4f
HNF4A hepatocyte nuclear factor 4, alpha
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IGHMBP2 immunoglobulin mu binding protein 2
IL6ST interleukin 6 signal transducer
IQCC IQ motif containing C
IRF2 interferon regulatory factor 2
KCNIP1 Kv channel interacting protein 1
KDM5A lysine (K)-specific demethylase 5A
KIAA0125 KIAA0125
KIAA0319L KIAA0319-like
KIAA0368 KIAA0368
KIAA1107 KIAA1107
KLF13 Kruppel-like factor 13
KLHL24 kelch-like family member 24
KMT2A lysine (K)-specific methyltransferase 2A
KRT15 keratin 15, type I
KYNU kynureninase
LAMP1 lysosomal-associated membrane protein 1
LGALS9 lectin, galactoside-binding, soluble, 9
LOC399491
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MED18 mediator complex subunit 18
METTL7A methyltransferase like 7A
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MYO1B myosin IB
N4BP3 NEDD4 binding protein 3
NEFL neurofilament, light polypeptide
NF2 neurofibromin 2 (merlin)
NMT2 N-myristoyltransferase 2
NUMA1 nuclear mitotic apparatus protein 1
PCDH7 protocadherin 7
PHF20L1 PHD finger protein 20-like 1
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
POLL polymerase (DNA directed), lambda
RABGAP1 RAB GTPase activating protein 1
RBP4 retinol binding protein 4, plasma
RHBDD3 rhomboid domain containing 3
RPL35A ribosomal protein L35a
RPS11 ribosomal protein S11
RSU1 Ras suppressor protein 1
SIPA1 signal-induced proliferation-associated 1
SLC13A3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SPPL2B signal peptide peptidase like 2B
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRAIP TRAF interacting protein
TRIB2 tribbles pseudokinase 2
UBXN1 UBX domain protein 1
UCN urocortin
VPS9D1 VPS9 domain containing 1
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF224 zinc finger protein 224
ZNF358 zinc finger protein 358
ZSCAN2 zinc finger and SCAN domain containing 2

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ADGRE5 adhesion G protein-coupled receptor E5
ALG12 ALG12, alpha-1,6-mannosyltransferase
ARFRP1 ADP-ribosylation factor related protein 1
AUTS2 autism susceptibility candidate 2
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BCORL1 BCL6 corepressor-like 1
C14ORF93 chromosome 14 open reading frame 93
C1ORF105 chromosome 1 open reading frame 105
C2ORF44 chromosome 2 open reading frame 44
CAMK4 calcium/calmodulin-dependent protein kinase IV
CCDC9 coiled-coil domain containing 9
CEP72 centrosomal protein 72kDa
COPZ2 coatomer protein complex, subunit zeta 2
CXORF56 chromosome X open reading frame 56
DDB1 damage-specific DNA binding protein 1, 127kDa
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
F3 coagulation factor III (thromboplastin, tissue factor)
FAN1 FANCD2/FANCI-associated nuclease 1
FKBP5 FK506 binding protein 5
FRS2 fibroblast growth factor receptor substrate 2
GCHFR GTP cyclohydrolase I feedback regulator
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GEMIN8 gem (nuclear organelle) associated protein 8
GLS2 glutaminase 2 (liver, mitochondrial)
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GRAMD3 GRAM domain containing 3
GTF2I general transcription factor IIi
H1F0 H1 histone family, member 0
HIST2H2AA3 histone cluster 2, H2aa3
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
HYI hydroxypyruvate isomerase (putative)
IFT81 intraflagellar transport 81
IL12RB1 interleukin 12 receptor, beta 1
IPO8 importin 8
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KIAA0754 KIAA0754
KLHL36 kelch-like family member 36
LARP6 La ribonucleoprotein domain family, member 6
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MBNL3 muscleblind-like splicing regulator 3
MBOAT2 membrane bound O-acyltransferase domain containing 2
MBTPS2 membrane-bound transcription factor peptidase, site 2
METTL16 methyltransferase like 16
MSI1 musashi RNA-binding protein 1
MTCP1 mature T-cell proliferation 1
MYO1F myosin IF
NDRG1 N-myc downstream regulated 1
NEK11 NIMA-related kinase 11
NPM3 nucleophosmin/nucleoplasmin 3
OCLM oculomedin
PCBP4 poly(rC) binding protein 4
PCDHB13 protocadherin beta 13
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PLAC1 placenta-specific 1
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PVRL3 poliovirus receptor-related 3
QPCTL glutaminyl-peptide cyclotransferase-like
RAB23 RAB23, member RAS oncogene family
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6
REPS2 RALBP1 associated Eps domain containing 2
RIN2 Ras and Rab interactor 2
RNF43 ring finger protein 43
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
RRAGB Ras-related GTP binding B
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SCN1B sodium channel, voltage gated, type I beta subunit
SCYL2 SCY1-like 2 (S. cerevisiae)
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLPI secretory leukocyte peptidase inhibitor
SP1 Sp1 transcription factor
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SRPX sushi-repeat containing protein, X-linked
STRN striatin, calmodulin binding protein
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TCTN2 tectonic family member 2
TLN1 talin 1
TMEM53 transmembrane protein 53
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TPSG1 tryptase gamma 1
TRIM5 tripartite motif containing 5
TSGA10 testis specific, 10
TUBA3C tubulin, alpha 3c
USB1 U6 snRNA biogenesis 1
USP27X ubiquitin specific peptidase 27, X-linked
WFDC2 WAP four-disulfide core domain 2
XYLT2 xylosyltransferase II
ZNF124 zinc finger protein 124
ZNF205 zinc finger protein 205
ZNF365 zinc finger protein 365
ZNF428 zinc finger protein 428
ZNF493 zinc finger protein 493