glutathione metabolic process Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific role in the reduction of hydrogen peroxide (H2O2) and oxidized ascorbate, and it participates in the gamma-glutamyl cycle. (Gene Ontology, GO_0006749)
External Link http://amigo.geneontology.org/amigo/term/GO:0006749
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Genes

44 genes participating in the glutathione metabolic process biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family)
CTNS cystinosin, lysosomal cystine transporter
DPEP1 dipeptidase 1 (renal)
ETHE1 ethylmalonic encephalopathy 1
G6PD glucose-6-phosphate dehydrogenase
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
GGCT gamma-glutamylcyclotransferase
GGT1 gamma-glutamyltransferase 1
GGT5 gamma-glutamyltransferase 5
GGT6 gamma-glutamyltransferase 6
GGT7 gamma-glutamyltransferase 7
GGTLC1 gamma-glutamyltransferase light chain 1
GGTLC2 gamma-glutamyltransferase light chain 2
GLO1 glyoxalase I
GLRX2 glutaredoxin 2
GPX1 glutathione peroxidase 1
GPX4 glutathione peroxidase 4
GSR glutathione reductase
GSS glutathione synthetase
GSTA1 glutathione S-transferase alpha 1
GSTA2 glutathione S-transferase alpha 2
GSTA3 glutathione S-transferase alpha 3
GSTA4 glutathione S-transferase alpha 4
GSTA5 glutathione S-transferase alpha 5
GSTK1 glutathione S-transferase kappa 1
GSTM1 glutathione S-transferase mu 1
GSTM2 glutathione S-transferase mu 2 (muscle)
GSTM3 glutathione S-transferase mu 3 (brain)
GSTM4 glutathione S-transferase mu 4
GSTM5 glutathione S-transferase mu 5
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
GSTZ1 glutathione S-transferase zeta 1
HAGH hydroxyacylglutathione hydrolase
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
MGST1 microsomal glutathione S-transferase 1
MGST2 microsomal glutathione S-transferase 2
NAT8 N-acetyltransferase 8 (GCN5-related, putative)
OPLAH 5-oxoprolinase (ATP-hydrolysing)
PNKD paroxysmal nonkinesigenic dyskinesia
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial