gliquidone-7301 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the gliquidone-7301 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADCY6 adenylate cyclase 6
ANGPTL4 angiopoietin-like 4
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ARNT aryl hydrocarbon receptor nuclear translocator
ARTN artemin
ATAD5 ATPase family, AAA domain containing 5
ATP7A ATPase, Cu++ transporting, alpha polypeptide
BCR breakpoint cluster region
C2ORF49 chromosome 2 open reading frame 49
C9ORF9 chromosome 9 open reading frame 9
CD47 CD47 molecule
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CLPS colipase, pancreatic
CTAGE5 CTAGE family, member 5
CXORF21 chromosome X open reading frame 21
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
DLX4 distal-less homeobox 4
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DOCK5 dedicator of cytokinesis 5
FA2H fatty acid 2-hydroxylase
FABP4 fatty acid binding protein 4, adipocyte
FLT1 fms-related tyrosine kinase 1
FLT3LG fms-related tyrosine kinase 3 ligand
FYB FYN binding protein
GATA2 GATA binding protein 2
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GPR107 G protein-coupled receptor 107
GPR85 G protein-coupled receptor 85
GTF2I general transcription factor IIi
HDAC7 histone deacetylase 7
HOXB6 homeobox B6
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IFI44L interferon-induced protein 44-like
IGLJ3 immunoglobulin lambda joining 3
IL1B interleukin 1, beta
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KAZN kazrin, periplakin interacting protein
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KCNIP1 Kv channel interacting protein 1
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KRT86 keratin 86, type II
LAMA4 laminin, alpha 4
LPIN1 lipin 1
LRP1 low density lipoprotein receptor-related protein 1
LRRK1 leucine-rich repeat kinase 1
LYPD3 LY6/PLAUR domain containing 3
MAP7 microtubule-associated protein 7
MAPT microtubule-associated protein tau
MARS methionyl-tRNA synthetase
MCAM melanoma cell adhesion molecule
MRPS12 mitochondrial ribosomal protein S12
MTAP methylthioadenosine phosphorylase
NF2 neurofibromin 2 (merlin)
NFYA nuclear transcription factor Y, alpha
NINJ1 ninjurin 1
NPIPB15 nuclear pore complex interacting protein family, member B15
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
PARP6 poly (ADP-ribose) polymerase family, member 6
PCSK6 proprotein convertase subtilisin/kexin type 6
PEX5 peroxisomal biogenesis factor 5
PHLDA3 pleckstrin homology-like domain, family A, member 3
PITX1 paired-like homeodomain 1
PLA2G5 phospholipase A2, group V
PLD1 phospholipase D1, phosphatidylcholine-specific
PLIN2 perilipin 2
PML promyelocytic leukemia
PODXL2 podocalyxin-like 2
PPP1R12B protein phosphatase 1, regulatory subunit 12B
PRKCD protein kinase C, delta
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTGIS prostaglandin I2 (prostacyclin) synthase
PTPRU protein tyrosine phosphatase, receptor type, U
RBPMS RNA binding protein with multiple splicing
RGCC regulator of cell cycle
RTEL1 regulator of telomere elongation helicase 1
SCAMP1 secretory carrier membrane protein 1
SCN10A sodium channel, voltage gated, type X alpha subunit
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SH3BP2 SH3-domain binding protein 2
SIGLEC6 sialic acid binding Ig-like lectin 6
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
TIAM1 T-cell lymphoma invasion and metastasis 1
TMEM63A transmembrane protein 63A
TMF1 TATA element modulatory factor 1
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TNK1 tyrosine kinase, non-receptor, 1
TSSK2 testis-specific serine kinase 2
VCL vinculin
VEGFA vascular endothelial growth factor A
WDR62 WD repeat domain 62
WIZ widely interspaced zinc finger motifs
WNT10B wingless-type MMTV integration site family, member 10B
ZNF41 zinc finger protein 41
ZNF783 zinc finger family member 783

decreased expression

Symbol Name
ABI3BP ABI family, member 3 (NESH) binding protein
ACOT8 acyl-CoA thioesterase 8
AGO1 argonaute RISC catalytic component 1
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
BNC2 basonuclin 2
C10ORF88 chromosome 10 open reading frame 88
C19ORF40 chromosome 19 open reading frame 40
C4ORF19 chromosome 4 open reading frame 19
CAPN5 calpain 5
CBR4 carbonyl reductase 4
CDON cell adhesion associated, oncogene regulated
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7
CHML choroideremia-like (Rab escort protein 2)
CINP cyclin-dependent kinase 2 interacting protein
CLDN15 claudin 15
COLGALT2 collagen beta(1-O)galactosyltransferase 2
CRELD1 cysteine-rich with EGF-like domains 1
CTGF connective tissue growth factor
CUL9 cullin 9
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
DAAM1 dishevelled associated activator of morphogenesis 1
DLK1 delta-like 1 homolog (Drosophila)
DNM1 dynamin 1
EAF2 ELL associated factor 2
EGF epidermal growth factor
EIF5A2 eukaryotic translation initiation factor 5A2
ERCC6 excision repair cross-complementation group 6
EYA4 EYA transcriptional coactivator and phosphatase 4
F2R coagulation factor II (thrombin) receptor
F3 coagulation factor III (thromboplastin, tissue factor)
FAM131B family with sequence similarity 131, member B
FAM155A family with sequence similarity 155, member A
FBXL15 F-box and leucine-rich repeat protein 15
FBXL2 F-box and leucine-rich repeat protein 2
FOXJ2 forkhead box J2
FRAT1 frequently rearranged in advanced T-cell lymphomas 1
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GPR137B G protein-coupled receptor 137B
HDAC5 histone deacetylase 5
HIST1H3G histone cluster 1, H3g
HLX H2.0-like homeobox
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
HSPB8 heat shock 22kDa protein 8
IGFLR1 IGF-like family receptor 1
IL18 interleukin 18
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
JUNB jun B proto-oncogene
L2HGDH L-2-hydroxyglutarate dehydrogenase
LOC100127972 uncharacterized LOC100127972
LYPD1 LY6/PLAUR domain containing 1
MAPK12 mitogen-activated protein kinase 12
MON1B MON1 secretory trafficking family member B
MRPL44 mitochondrial ribosomal protein L44
MTERF1 mitochondrial transcription termination factor 1
MUTYH mutY homolog
NLRX1 NLR family member X1
NPR3 natriuretic peptide receptor 3
NRSN2 neurensin 2
NT5DC3 5'-nucleotidase domain containing 3
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
NXPH4 neurexophilin 4
OTUD3 OTU deubiquitinase 3
PCOLCE procollagen C-endopeptidase enhancer
PDLIM2 PDZ and LIM domain 2 (mystique)
PEX13 peroxisomal biogenesis factor 13
PLCD1 phospholipase C, delta 1
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
POU2F1 POU class 2 homeobox 1
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PTX3 pentraxin 3, long
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RNF121 ring finger protein 121
S100A3 S100 calcium binding protein A3
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SLC12A8 solute carrier family 12, member 8
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SNX10 sorting nexin 10
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
ST5 suppression of tumorigenicity 5
STAR steroidogenic acute regulatory protein
TBXAS1 thromboxane A synthase 1 (platelet)
TKFC triokinase/FMN cyclase
TMEM156 transmembrane protein 156
TMEM62 transmembrane protein 62
TRAIP TRAF interacting protein
TRIM45 tripartite motif containing 45
TRIM66 tripartite motif containing 66
TYK2 tyrosine kinase 2
WDR91 WD repeat domain 91
WNT7A wingless-type MMTV integration site family, member 7A
ZFP36 ZFP36 ring finger protein
ZHX2 zinc fingers and homeoboxes 2
ZNF358 zinc finger protein 358
ZNF580 zinc finger protein 580
ZNF804A zinc finger protein 804A
ZNF84 zinc finger protein 84