gliquidone-6004 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the gliquidone-6004 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACHE acetylcholinesterase (Yt blood group)
ADRBK1 adrenergic, beta, receptor kinase 1
AGFG2 ArfGAP with FG repeats 2
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
ARMC4 armadillo repeat containing 4
ARNT aryl hydrocarbon receptor nuclear translocator
ATXN2L ataxin 2-like
BCAT1 branched chain amino-acid transaminase 1, cytosolic
BTBD7 BTB (POZ) domain containing 7
C11ORF16 chromosome 11 open reading frame 16
CCL17 chemokine (C-C motif) ligand 17
CD58 CD58 molecule
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CHM choroideremia (Rab escort protein 1)
CLIC5 chloride intracellular channel 5
CUL2 cullin 2
CXCL8 chemokine (C-X-C motif) ligand 8
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DFNB31 deafness, autosomal recessive 31
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DRD2 dopamine receptor D2
EPHX2 epoxide hydrolase 2, cytoplasmic
FAM135A family with sequence similarity 135, member A
FAM182B family with sequence similarity 182, member B
FAM212B family with sequence similarity 212, member B
FANCA Fanconi anemia, complementation group A
FHIT fragile histidine triad
FSHB follicle stimulating hormone, beta polypeptide
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
GBP1 guanylate binding protein 1, interferon-inducible
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
HIST1H2AB histone cluster 1, H2ab
HOXB3 homeobox B3
HOXC5 homeobox C5
HP haptoglobin
IGFBP7 insulin-like growth factor binding protein 7
KDM8 lysine (K)-specific demethylase 8
LOC157562 uncharacterized LOC157562
LOXL2 lysyl oxidase-like 2
LTBP4 latent transforming growth factor beta binding protein 4
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MRPS18C mitochondrial ribosomal protein S18C
MSI1 musashi RNA-binding protein 1
MYBPC3 myosin binding protein C, cardiac
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NEIL1 nei endonuclease VIII-like 1 (E. coli)
NTN1 netrin 1
NTS neurotensin
PADI1 peptidyl arginine deiminase, type I
PAX2 paired box 2
PAX6 paired box 6
PCDH12 protocadherin 12
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDIA2 protein disulfide isomerase family A, member 2
PHOX2A paired-like homeobox 2a
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PRDM14 PR domain containing 14
PRKCA protein kinase C, alpha
PTK6 protein tyrosine kinase 6
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
PWAR5 Prader Willi/Angelman region RNA 5
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RB1 retinoblastoma 1
RHBDD3 rhomboid domain containing 3
RNF122 ring finger protein 122
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SGSM3 small G protein signaling modulator 3
SH2D3A SH2 domain containing 3A
SH3BP2 SH3-domain binding protein 2
SIGLEC6 sialic acid binding Ig-like lectin 6
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SPIB Spi-B transcription factor (Spi-1/PU.1 related)
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6
STAG3L4 stromal antigen 3-like 4 (pseudogene)
SUGP1 SURP and G patch domain containing 1
TBC1D8 TBC1 domain family, member 8 (with GRAM domain)
TBL2 transducin (beta)-like 2
TGFBR1 transforming growth factor, beta receptor 1
TLK1 tousled-like kinase 1
TM4SF1 transmembrane 4 L six family member 1
TMEM120B transmembrane protein 120B
TMOD1 tropomodulin 1
TRIM21 tripartite motif containing 21
TRIM3 tripartite motif containing 3
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VAV2 vav 2 guanine nucleotide exchange factor
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VPS13B vacuolar protein sorting 13 homolog B (yeast)
WLS wntless Wnt ligand secretion mediator
WNT8B wingless-type MMTV integration site family, member 8B

decreased expression

Symbol Name
ACSL4 acyl-CoA synthetase long-chain family member 4
ADAM23 ADAM metallopeptidase domain 23
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARC activity-regulated cytoskeleton-associated protein
ARRB1 arrestin, beta 1
ASPHD1 aspartate beta-hydroxylase domain containing 1
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BGLAP bone gamma-carboxyglutamate (gla) protein
C11ORF63 chromosome 11 open reading frame 63
C17ORF70 chromosome 17 open reading frame 70
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CAPN5 calpain 5
CARTPT CART prepropeptide
CCNE1 cyclin E1
CHKB choline kinase beta
CLDN15 claudin 15
CNGB3 cyclic nucleotide gated channel beta 3
CORO1A coronin, actin binding protein, 1A
CRYBB2P1 crystallin, beta B2 pseudogene 1
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DGAT1 diacylglycerol O-acyltransferase 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM120C family with sequence similarity 120C
FGL1 fibrinogen-like 1
FILIP1L filamin A interacting protein 1-like
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GBP2 guanylate binding protein 2, interferon-inducible
GPATCH2L G patch domain containing 2-like
HIST1H2BN histone cluster 1, H2bn
HOXA4 homeobox A4
HYI hydroxypyruvate isomerase (putative)
IDI2-AS1 IDI2 antisense RNA 1
IFI6 interferon, alpha-inducible protein 6
IFITM1 interferon induced transmembrane protein 1
IRF2 interferon regulatory factor 2
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KIAA1456 KIAA1456
KPTN kaptin (actin binding protein)
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LPXN leupaxin
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRRC8E leucine rich repeat containing 8 family, member E
LTBP2 latent transforming growth factor beta binding protein 2
MANBA mannosidase, beta A, lysosomal
MEIS1 Meis homeobox 1
MRAS muscle RAS oncogene homolog
MTCL1 microtubule crosslinking factor 1
NDE1 nudE neurodevelopment protein 1
NR1H2 nuclear receptor subfamily 1, group H, member 2
NXPH4 neurexophilin 4
ONECUT2 one cut homeobox 2
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PCSK7 proprotein convertase subtilisin/kexin type 7
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PLA2G3 phospholipase A2, group III
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
POLH polymerase (DNA directed), eta
PROCR protein C receptor, endothelial
PRODH proline dehydrogenase (oxidase) 1
PTPRS protein tyrosine phosphatase, receptor type, S
RANBP17 RAN binding protein 17
REM1 RAS (RAD and GEM)-like GTP-binding 1
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RIN1 Ras and Rab interactor 1
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPH3AL rabphilin 3A-like (without C2 domains)
SLC22A14 solute carrier family 22, member 14
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SND1-IT1 SND1 intronic transcript 1
SP1 Sp1 transcription factor
SPRR2B small proline-rich protein 2B
SREK1IP1 SREK1-interacting protein 1
STXBP2 syntaxin binding protein 2
TLR5 toll-like receptor 5
TMEM183A transmembrane protein 183A
TMEM212 transmembrane protein 212
TMEM51 transmembrane protein 51
TMEM62 transmembrane protein 62
TTBK2 tau tubulin kinase 2
TUBA3C tubulin, alpha 3c
UPK2 uroplakin 2
UPP1 uridine phosphorylase 1
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VNN2 vanin 2
WDR62 WD repeat domain 62
XK X-linked Kx blood group
ZBED1 zinc finger, BED-type containing 1
ZBTB22 zinc finger and BTB domain containing 22
ZFP37 ZFP37 zinc finger protein
ZNF573 zinc finger protein 573
ZNF711 zinc finger protein 711