glioblastoma Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description The most malignant astrocytic tumor (WHO grade IV). It is composed of poorly differentiated neoplastic astrocytes and it is characterized by the presence of cellular polymorphism, nuclear atypia, brisk mitotic activity, vascular thrombosis, microvascular proliferation and necrosis. It typically affects adults and is preferentially located in the cerebral hemispheres. It may develop from diffuse astrocytoma WHO grade II or anaplastic astrocytoma (secondary glioblastoma), but more frequently, it manifests after a short clinical history de novo, without evidence of a less malignant precursor lesion (primary glioblastoma). Two histologic variants are recognized: giant cell glioblastoma and gliosarcoma. (WHO)|Glial cell derived tumors arising from the optic nerve, usually presenting in childhood. Roughly 50% are associated with NEUROFIBROMATOSIS 1. Clinical manifestations include decreased visual acuity; EXOPHTHALMOS; NYSTAGMUS, PATHOLOGIC; STRABISMUS; pallor or swelling of the optic disc; and INTRACRANIAL HYPERTENSION. The tumor may extend into the optic chiasm and hypothalamus (MeSH).|A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures (MeSH).|A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures. (Experimental Factor Ontology, EFO_0000519)
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Genes

673 genes co-occuring with the biological term glioblastoma in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACKR3 atypical chemokine receptor 3
ACLY ATP citrate lyase
ADAM10 ADAM metallopeptidase domain 10
ADAM17 ADAM metallopeptidase domain 17
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADARB1 adenosine deaminase, RNA-specific, B1
ADGRB1 adhesion G protein-coupled receptor B1
ADGRE2 adhesion G protein-coupled receptor E2
ADGRE5 adhesion G protein-coupled receptor E5
ADIPOQ adiponectin, C1Q and collagen domain containing
ADM adrenomedullin
ADRBK2 adrenergic, beta, receptor kinase 2
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AGRN agrin
AHSG alpha-2-HS-glycoprotein
AIM2 absent in melanoma 2
AJAP1 adherens junctions associated protein 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALCAM activated leukocyte cell adhesion molecule
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALK anaplastic lymphoma receptor tyrosine kinase
ALKBH2 alkB, alkylation repair homolog 2 (E. coli)
ALOX5 arachidonate 5-lipoxygenase
ANGPT1 angiopoietin 1
ANXA7 annexin A7
APAF1 apoptotic peptidase activating factor 1
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
API5 apoptosis inhibitor 5
APOD apolipoprotein D
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
AQP1 aquaporin 1 (Colton blood group)
AQP4 aquaporin 4
AQP8 aquaporin 8
AQP9 aquaporin 9
AREG amphiregulin
ARF4 ADP-ribosylation factor 4
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ATAD3A ATPase family, AAA domain containing 3A
ATF5 activating transcription factor 5
ATM ATM serine/threonine kinase
AURKA aurora kinase A
AURKB aurora kinase B
AXIN1 axin 1
BAG3 BCL2-associated athanogene 3
BAX BCL2-associated X protein
BBC3 BCL2 binding component 3
BCAN brevican
BCAT1 branched chain amino-acid transaminase 1, cytosolic
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCL2L12 BCL2-like 12 (proline rich)
BCL2L2 BCL2-like 2
BCL6 B-cell CLL/lymphoma 6
BECN1 beclin 1, autophagy related
BIRC5 baculoviral IAP repeat containing 5
BIRC7 baculoviral IAP repeat containing 7
BLVRA biliverdin reductase A
BMI1 BMI1 proto-oncogene, polycomb ring finger
BMX BMX non-receptor tyrosine kinase
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BRAF B-Raf proto-oncogene, serine/threonine kinase
BSG basigin (Ok blood group)
BTBD2 BTB (POZ) domain containing 2
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
CA9 carbonic anhydrase IX
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3
CADM1 cell adhesion molecule 1
CAPN2 calpain 2, (m/II) large subunit
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC26 CCDC26 long non-coding RNA
CCDC88A coiled-coil domain containing 88A
CCL2 chemokine (C-C motif) ligand 2
CCL3 chemokine (C-C motif) ligand 3
CCND1 cyclin D1
CCND2 cyclin D2
CCR2 chemokine (C-C motif) receptor 2
CD14 CD14 molecule
CD24 CD24 molecule
CD274 CD274 molecule
CD34 CD34 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD44 CD44 molecule (Indian blood group)
CD70 CD70 molecule
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDH19 cadherin 19, type 2
CDH5 cadherin 5, type 2 (vascular endothelium)
CDK20 cyclin-dependent kinase 20
CDK3 cyclin-dependent kinase 3
CDK4 cyclin-dependent kinase 4
CDK5 cyclin-dependent kinase 5
CDK6 cyclin-dependent kinase 6
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CFL1 cofilin 1 (non-muscle)
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHRM2 cholinergic receptor, muscarinic 2
CITED4 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
CLDN1 claudin 1
CNDP1 carnosine dipeptidase 1 (metallopeptidase M20 family)
CNR2 cannabinoid receptor 2 (macrophage)
COL4A2 collagen, type IV, alpha 2
CORO1A coronin, actin binding protein, 1A
CPT1A carnitine palmitoyltransferase 1A (liver)
CPT1C carnitine palmitoyltransferase 1C
CREB1 cAMP responsive element binding protein 1
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRMP1 collapsin response mediator protein 1
CRYAA crystallin, alpha A
CRYAB crystallin, alpha B
CSF1 colony stimulating factor 1 (macrophage)
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CSPG4 chondroitin sulfate proteoglycan 4
CST3 cystatin C
CSTB cystatin B (stefin B)
CTGF connective tissue growth factor
CTSB cathepsin B
CTSL cathepsin L
CTSS cathepsin S
CTTN cortactin
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR3 chemokine (C-X-C motif) receptor 3
CXCR4 chemokine (C-X-C motif) receptor 4
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
D2HGDH D-2-hydroxyglutarate dehydrogenase
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DAOA D-amino acid oxidase activator
DDB2 damage-specific DNA binding protein 2, 48kDa
DDIT3 DNA-damage-inducible transcript 3
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56
DEFB126 defensin, beta 126
DGKA diacylglycerol kinase, alpha 80kDa
DHPS deoxyhypusine synthase
DKK1 dickkopf WNT signaling pathway inhibitor 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
DLL4 delta-like 4 (Drosophila)
DLX2 distal-less homeobox 2
DNM1L dynamin 1-like
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DOCK1 dedicator of cytokinesis 1
DOCK7 dedicator of cytokinesis 7
DOHH deoxyhypusine hydroxylase/monooxygenase
DPP3 dipeptidyl-peptidase 3
DPP4 dipeptidyl-peptidase 4
DRD2 dopamine receptor D2
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial
ECT2 epithelial cell transforming 2
EDN1 endothelin 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EFNB3 ephrin-B3
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EGR1 early growth response 1
EIF3B eukaryotic translation initiation factor 3, subunit B
EIF3E eukaryotic translation initiation factor 3, subunit E
EIF5A eukaryotic translation initiation factor 5A
EIF5A2 eukaryotic translation initiation factor 5A2
ELAVL1 ELAV like RNA binding protein 1
ELK1 ELK1, member of ETS oncogene family
EMP3 epithelial membrane protein 3
ENO1 enolase 1, (alpha)
ENO2 enolase 2 (gamma, neuronal)
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
EP300 E1A binding protein p300
EPAS1 endothelial PAS domain protein 1
EPHA2 EPH receptor A2
EPHA3 EPH receptor A3
EPHA4 EPH receptor A4
EPHA7 EPH receptor A7
EPHB2 EPH receptor B2
EPHB4 EPH receptor B4
EPS8 epidermal growth factor receptor pathway substrate 8
ERBB2 erb-b2 receptor tyrosine kinase 2
ERCC1 excision repair cross-complementation group 1
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
EZR ezrin
F2 coagulation factor II (thrombin)
F2RL1 coagulation factor II (thrombin) receptor-like 1
F3 coagulation factor III (thromboplastin, tissue factor)
FABP7 fatty acid binding protein 7, brain
FAP fibroblast activation protein, alpha
FAS Fas cell surface death receptor
FASN fatty acid synthase
FGFR1 fibroblast growth factor receptor 1
FGFR3 fibroblast growth factor receptor 3
FHIT fragile histidine triad
FHL2 four and a half LIM domains 2
FLT1 fms-related tyrosine kinase 1
FLT3LG fms-related tyrosine kinase 3 ligand
FN1 fibronectin 1
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FOXM1 forkhead box M1
FOXO1 forkhead box O1
FOXO3 forkhead box O3
FOXP3 forkhead box P3
FPR1 formyl peptide receptor 1
FRAT1 frequently rearranged in advanced T-cell lymphomas 1
FST follistatin
FTL ferritin, light polypeptide
FYN FYN proto-oncogene, Src family tyrosine kinase
GAB1 GRB2-associated binding protein 1
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1
GALNT13 polypeptide N-acetylgalactosaminyltransferase 13
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GATA4 GATA binding protein 4
GATA6 GATA binding protein 6
GDF15 growth differentiation factor 15
GFAP glial fibrillary acidic protein
GJA1 gap junction protein, alpha 1, 43kDa
GLI1 GLI family zinc finger 1
GLS2 glutaminase 2 (liver, mitochondrial)
GLTSCR2 glioma tumor suppressor candidate region gene 2
GLUD1 glutamate dehydrogenase 1
GLUL glutamate-ammonia ligase
GNAS GNAS complex locus
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GOLPH3 golgi phosphoprotein 3 (coat-protein)
GPR26 G protein-coupled receptor 26
GPX1 glutathione peroxidase 1
GREM1 gremlin 1, DAN family BMP antagonist
GRIA1 glutamate receptor, ionotropic, AMPA 1
GSK3B glycogen synthase kinase 3 beta
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HDGF hepatoma-derived growth factor
HES1 hes family bHLH transcription factor 1
HES3 hes family bHLH transcription factor 3
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HK2 hexokinase 2
HLA-A major histocompatibility complex, class I, A
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-E major histocompatibility complex, class I, E
HLA-G major histocompatibility complex, class I, G
HMGA1 high mobility group AT-hook 1
HMGA2 high mobility group AT-hook 2
HMGB1 high mobility group box 1
HMGB2 high mobility group box 2
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2)
HOTAIR HOX transcript antisense RNA
HOXA10 homeobox A10
HOXA11 homeobox A11
HOXA9 homeobox A9
HOXB7 homeobox B7
HPSE heparanase
HRAS Harvey rat sarcoma viral oncogene homolog
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AA2P heat shock protein 90kDa alpha (cytosolic), class A member 2, pseudogene
HSPB8 heat shock 22kDa protein 8
ICK intestinal cell (MAK-like) kinase
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IDO1 indoleamine 2,3-dioxygenase 1
IFNG interferon, gamma
IFT57 intraflagellar transport 57
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP3 insulin-like growth factor binding protein 3
IGFBP4 insulin-like growth factor binding protein 4
IGFBP7 insulin-like growth factor binding protein 7
IL10 interleukin 10
IL13 interleukin 13
IL13RA2 interleukin 13 receptor, alpha 2
IL17A interleukin 17A
IL1B interleukin 1, beta
IL24 interleukin 24
IL4R interleukin 4 receptor
IL6 interleukin 6
ING1 inhibitor of growth family, member 1
ING4 inhibitor of growth family, member 4
INHBA inhibin, beta A
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGA6 integrin, alpha 6
ITGA7 integrin, alpha 7
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB8 integrin, beta 8
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
ITSN1 intersectin 1 (SH3 domain protein)
JAG1 jagged 1
JAK2 Janus kinase 2
JUN jun proto-oncogene
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1
KCNK9 potassium channel, two pore domain subfamily K, member 9
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KDR kinase insert domain receptor
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KIR2DS2 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KITLG KIT ligand
KLF4 Kruppel-like factor 4 (gut)
KLF6 Kruppel-like factor 6
KLF9 Kruppel-like factor 9
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KMT2A lysine (K)-specific methyltransferase 2A
KRAS Kirsten rat sarcoma viral oncogene homolog
L2HGDH L-2-hydroxyglutarate dehydrogenase
LAMA3 laminin, alpha 3
LAMC1 laminin, gamma 1 (formerly LAMB2)
LDHA lactate dehydrogenase A
LEF1 lymphoid enhancer-binding factor 1
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS3 lectin, galactoside-binding, soluble, 3
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LIG4 ligase IV, DNA, ATP-dependent
LIMK1 LIM domain kinase 1
LIN28A lin-28 homolog A (C. elegans)
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase
LRP1 low density lipoprotein receptor-related protein 1
LRP6 low density lipoprotein receptor-related protein 6
LRRC4 leucine rich repeat containing 4
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LY96 lymphocyte antigen 96
LYN LYN proto-oncogene, Src family tyrosine kinase
MAF1 MAF1 homolog (S. cerevisiae)
MAK male germ cell-associated kinase
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MCL1 myeloid cell leukemia 1
MCM7 minichromosome maintenance complex component 7
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MELK maternal embryonic leucine zipper kinase
MERTK MER proto-oncogene, tyrosine kinase
MET MET proto-oncogene, receptor tyrosine kinase
MGMT O-6-methylguanine-DNA methyltransferase
MGP matrix Gla protein
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR101-1 microRNA 101-1
MIR101-2 microRNA 101-2
MIR106A microRNA 106a
MIR10A microRNA 10a
MIR10B microRNA 10b
MIR122 microRNA 122
MIR124-1 microRNA 124-1
MIR125B1 microRNA 125b-1
MIR125B2 microRNA 125b-2
MIR127 microRNA 127
MIR128-1 microRNA 128-1
MIR137 microRNA 137
MIR143 microRNA 143
MIR145 microRNA 145
MIR146B microRNA 146b
MIR152 microRNA 152
MIR155 microRNA 155
MIR17 microRNA 17
MIR17HG miR-17-92 cluster host gene
MIR181C microRNA 181c
MIR181D microRNA 181d
MIR182 microRNA 182
MIR18A microRNA 18a
MIR195 microRNA 195
MIR196A1 microRNA 196a-1
MIR196A2 microRNA 196a-2
MIR197 microRNA 197
MIR20A microRNA 20a
MIR21 microRNA 21
MIR214 microRNA 214
MIR218-1 microRNA 218-1
MIR218-2 microRNA 218-2
MIR219A1 microRNA 219a-1
MIR221 microRNA 221
MIR222 microRNA 222
MIR223 microRNA 223
MIR224 microRNA 224
MIR25 microRNA 25
MIR26A1 microRNA 26a-1
MIR27A microRNA 27a
MIR296 microRNA 296
MIR297 microRNA 297
MIR29C microRNA 29c
MIR31 microRNA 31
MIR32 microRNA 32
MIR320A microRNA 320a
MIR326 microRNA 326
MIR328 microRNA 328
MIR330 microRNA 330
MIR34A microRNA 34a
MIR451A microRNA 451a
MIR495 microRNA 495
MIR503 microRNA 503
MIR504 microRNA 504
MIR519D microRNA 519d
MIR574 microRNA 574
MIR663A microRNA 663a
MIR7-1 microRNA 7-1
MIR7-2 microRNA 7-2
MIR7-3 microRNA 7-3
MIR9-1 microRNA 9-1
MIR9-2 microRNA 9-2
MIR9-3 microRNA 9-3
MIR99A microRNA 99a
MIRLET7A1 microRNA let-7a-1
MKI67 marker of proliferation Ki-67
MLH1 mutL homolog 1
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MOB4 MOB family member 4, phocein
MSH2 mutS homolog 2
MSH6 mutS homolog 6
MSI1 musashi RNA-binding protein 1
MST1 macrophage stimulating 1
MTDH metadherin
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MVP major vault protein
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYT1L myelin transcription factor 1-like
NAIP NLR family, apoptosis inhibitory protein
NANOG Nanog homeobox
NANOGP8 Nanog homeobox pseudogene 8
NCOR1 nuclear receptor corepressor 1
NDRG1 N-myc downstream regulated 1
NDRG2 NDRG family member 2
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NEO1 neogenin 1
NES nestin
NEWENTRY Record to support submission of GeneRIFs for a gene not in Gene (human; man).
NF1 neurofibromin 1
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NGB neuroglobin
NNAT neuronatin
NOTCH1 notch 1
NOTCH4 notch 4
NOV nephroblastoma overexpressed
NOX4 NADPH oxidase 4
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NPTX2 neuronal pentraxin II
NRP1 neuropilin 1
NT5E 5'-nucleotidase, ecto (CD73)
NTN1 netrin 1
NTN4 netrin 4
NUMA1 nuclear mitotic apparatus protein 1
OLIG2 oligodendrocyte lineage transcription factor 2
ORAI1 ORAI calcium release-activated calcium modulator 1
PARP1 poly (ADP-ribose) polymerase 1
PAX6 paired box 6
PCDH10 protocadherin 10
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PDPN podoplanin
PDS5A PDS5 cohesin associated factor A
PEA15 phosphoprotein enriched in astrocytes 15
PHF20 PHD finger protein 20
PHF3 PHD finger protein 3
PHLDB1 pleckstrin homology-like domain, family B, member 1
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PI3 peptidase inhibitor 3, skin-derived
PIAS3 protein inhibitor of activated STAT, 3
PIBF1 progesterone immunomodulatory binding factor 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PKD2 polycystic kidney disease 2 (autosomal dominant)
PKM pyruvate kinase, muscle
PLAU plasminogen activator, urokinase
PLAUR plasminogen activator, urokinase receptor
PLD2 phospholipase D2
PLK1 polo-like kinase 1
PLK5 polo-like kinase 5
PML promyelocytic leukemia
PODXL podocalyxin-like
POLR1B polymerase (RNA) I polypeptide B, 128kDa
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa
POU5F1 POU class 5 homeobox 1
PPARG peroxisome proliferator-activated receptor gamma
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPIB peptidylprolyl isomerase B (cyclophilin B)
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4
PRDX4 peroxiredoxin 4
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKCA protein kinase C, alpha
PRKCD protein kinase C, delta
PRKCH protein kinase C, eta
PRKCI protein kinase C, iota
PRKCZ protein kinase C, zeta
PRKD2 protein kinase D2
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PROM1 prominin 1
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PTBP1 polypyrimidine tract binding protein 1
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTN pleiotrophin
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPRD protein tyrosine phosphatase, receptor type, D
PTPRM protein tyrosine phosphatase, receptor type, M
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1
PTX3 pentraxin 3, long
PYCARD PYD and CARD domain containing
PYGO2 pygopus family PHD finger 2
RAD18 RAD18 E3 ubiquitin protein ligase
RAD51B RAD51 paralog B
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RAP1A RAP1A, member of RAS oncogene family
RB1 retinoblastoma 1
RB1CC1 RB1-inducible coiled-coil 1
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RBM14 RNA binding motif protein 14
RECK reversion-inducing-cysteine-rich protein with kazal motifs
RECQL4 RecQ protein-like 4
REST RE1-silencing transcription factor
RET ret proto-oncogene
RHOA ras homolog family member A
RHOB ras homolog family member B
RICTOR RPTOR independent companion of MTOR, complex 2
RINT1 RAD50 interactor 1
RIOK1 RIO kinase 1
RIOK2 RIO kinase 2
RMDN3 regulator of microtubule dynamics 3
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RPTOR regulatory associated protein of MTOR, complex 1
RTEL1 regulator of telomere elongation helicase 1
S100A9 S100 calcium binding protein A9
S1PR1 sphingosine-1-phosphate receptor 1
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SAT1 spermidine/spermine N1-acetyltransferase 1
SCG5 secretogranin V
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SESN2 sestrin 2
SH3GL2 SH3-domain GRB2-like 2
SHH sonic hedgehog
SIK1 salt-inducible kinase 1
SIRT2 sirtuin 2
SKAP2 src kinase associated phosphoprotein 2
SLC38A3 solute carrier family 38, member 3
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SMC1A structural maintenance of chromosomes 1A
SNAI1 snail family zinc finger 1
SOCS1 suppressor of cytokine signaling 1
SOCS3 suppressor of cytokine signaling 3
SOD2 superoxide dismutase 2, mitochondrial
SOS1 son of sevenless homolog 1 (Drosophila)
SOX2 SRY (sex determining region Y)-box 2
SOX4 SRY (sex determining region Y)-box 4
SP1 Sp1 transcription factor
SPHK1 sphingosine kinase 1
SPP1 secreted phosphoprotein 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SSBP2 single-stranded DNA binding protein 2
SSTR2 somatostatin receptor 2
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STC2 stanniocalcin 2
STIM1 stromal interaction molecule 1
STK11 serine/threonine kinase 11
SYNM synemin, intermediate filament protein
TACC1 transforming, acidic coiled-coil containing protein 1
TACC3 transforming, acidic coiled-coil containing protein 3
TAPBP TAP binding protein (tapasin)
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TCTN1 tectonic family member 1
TERT telomerase reverse transcriptase
TFPI2 tissue factor pathway inhibitor 2
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TGFBR1 transforming growth factor, beta receptor 1
TIMP1 TIMP metallopeptidase inhibitor 1
TKTL1 transketolase-like 1
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR9 toll-like receptor 9
TMSB4X thymosin beta 4, X-linked
TNC tenascin C
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFRSF19 tumor necrosis factor receptor superfamily, member 19
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TOP1 topoisomerase (DNA) I
TOP2A topoisomerase (DNA) II alpha 170kDa
TP53 tumor protein p53
TRAF2 TNF receptor-associated factor 2
TRIO trio Rho guanine nucleotide exchange factor
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TRPC6 transient receptor potential cation channel, subfamily C, member 6
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSPO translocator protein (18kDa)
TWIST1 twist family bHLH transcription factor 1
TXNRD1 thioredoxin reductase 1
TYMS thymidylate synthetase
ULK2 unc-51 like autophagy activating kinase 2
USP10 ubiquitin specific peptidase 10
USP15 ubiquitin specific peptidase 15
USP2 ubiquitin specific peptidase 2
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VAV3 vav 3 guanine nucleotide exchange factor
VCAN versican
VCP valosin containing protein
VEGFA vascular endothelial growth factor A
VIM vimentin
WASF2 WAS protein family, member 2
WEE1 WEE1 G2 checkpoint kinase
WIF1 WNT inhibitory factor 1
WNT3A wingless-type MMTV integration site family, member 3A
WT1 Wilms tumor 1
WWOX WW domain containing oxidoreductase
XIST X inactive specific transcript (non-protein coding)
XPC xeroderma pigmentosum, complementation group C
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
YAP1 Yes-associated protein 1
YBX1 Y box binding protein 1
YEATS4 YEATS domain containing 4
YES1 YES proto-oncogene 1, Src family tyrosine kinase
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZEB1 zinc finger E-box binding homeobox 1
ZFP57 ZFP57 zinc finger protein