Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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195 genes differentially expressed following the glimepiride-6628 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ACTG2 | actin, gamma 2, smooth muscle, enteric |
AIM2 | absent in melanoma 2 |
ANGPTL4 | angiopoietin-like 4 |
ARHGAP35 | Rho GTPase activating protein 35 |
ARTN | artemin |
ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
BDKRB2 | bradykinin receptor B2 |
BGN | biglycan |
C1QL1 | complement component 1, q subcomponent-like 1 |
CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
CAMSAP1 | calmodulin regulated spectrin-associated protein 1 |
CCDC181 | coiled-coil domain containing 181 |
CD47 | CD47 molecule |
CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
CERS4 | ceramide synthase 4 |
CHI3L2 | chitinase 3-like 2 |
COBL | cordon-bleu WH2 repeat protein |
COL5A1 | collagen, type V, alpha 1 |
CYTH3 | cytohesin 3 |
DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A |
EFNA3 | ephrin-A3 |
EHD2 | EH-domain containing 2 |
EXOC7 | exocyst complex component 7 |
FABP4 | fatty acid binding protein 4, adipocyte |
FBXO41 | F-box protein 41 |
FGFR1 | fibroblast growth factor receptor 1 |
FLT1 | fms-related tyrosine kinase 1 |
FUBP1 | far upstream element (FUSE) binding protein 1 |
G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 |
GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 |
GNAQ | guanine nucleotide binding protein (G protein), q polypeptide |
GP6 | glycoprotein VI (platelet) |
GPR21 | G protein-coupled receptor 21 |
GRIA1 | glutamate receptor, ionotropic, AMPA 1 |
GRIK1 | glutamate receptor, ionotropic, kainate 1 |
GSTTP1 | glutathione S-transferase theta pseudogene 1 |
HAP1 | huntingtin-associated protein 1 |
HIPK3 | homeodomain interacting protein kinase 3 |
HIST1H3I | histone cluster 1, H3i |
HRG | histidine-rich glycoprotein |
HSF1 | heat shock transcription factor 1 |
HTR4 | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
IDS | iduronate 2-sulfatase |
IFT122 | intraflagellar transport 122 |
KAZALD1 | Kazal-type serine peptidase inhibitor domain 1 |
KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
KCTD14 | potassium channel tetramerization domain containing 14 |
KIF25 | kinesin family member 25 |
KITLG | KIT ligand |
KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
LOC57399 | uncharacterized gastric protein ZA52P |
LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
MAB21L1 | mab-21-like 1 (C. elegans) |
MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 |
NRCAM | neuronal cell adhesion molecule |
NRTN | neurturin |
NTNG1 | netrin G1 |
PAPPA2 | pappalysin 2 |
PARK2 | parkin RBR E3 ubiquitin protein ligase |
PLCH2 | phospholipase C, eta 2 |
PLIN2 | perilipin 2 |
PLXNB2 | plexin B2 |
POMT2 | protein-O-mannosyltransferase 2 |
PPARD | peroxisome proliferator-activated receptor delta |
PRDM1 | PR domain containing 1, with ZNF domain |
PRKCA | protein kinase C, alpha |
PSG4 | pregnancy specific beta-1-glycoprotein 4 |
PTCRA | pre T-cell antigen receptor alpha |
PTGDS | prostaglandin D2 synthase 21kDa (brain) |
PTPRB | protein tyrosine phosphatase, receptor type, B |
RASAL2 | RAS protein activator like 2 |
RBM34 | RNA binding motif protein 34 |
RBMS2 | RNA binding motif, single stranded interacting protein 2 |
RGS5 | regulator of G-protein signaling 5 |
RPA4 | replication protein A4, 30kDa |
RPL35A | ribosomal protein L35a |
SAGE1 | sarcoma antigen 1 |
SGK2 | serum/glucocorticoid regulated kinase 2 |
SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
SSTR5 | somatostatin receptor 5 |
STRA6 | stimulated by retinoic acid 6 |
TFEB | transcription factor EB |
TGM4 | transglutaminase 4 |
THOC5 | THO complex 5 |
TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
TRD | T cell receptor delta locus |
TRIM29 | tripartite motif containing 29 |
UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
URB1 | URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
UTP14A | UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) |
VAPB | VAMP (vesicle-associated membrane protein)-associated protein B and C |
VGF | VGF nerve growth factor inducible |
ZNF280A | zinc finger protein 280A |
ZNF573 | zinc finger protein 573 |
Symbol | Name |
---|---|
ABCB8 | ATP-binding cassette, sub-family B (MDR/TAP), member 8 |
ALPK1 | alpha-kinase 1 |
ALS2CL | ALS2 C-terminal like |
AMPD2 | adenosine monophosphate deaminase 2 |
ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
ANXA2P3 | annexin A2 pseudogene 3 |
ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
BDNF | brain-derived neurotrophic factor |
C14ORF79 | chromosome 14 open reading frame 79 |
CDON | cell adhesion associated, oncogene regulated |
CIDEB | cell death-inducing DFFA-like effector b |
CLCN5 | chloride channel, voltage-sensitive 5 |
CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
COLGALT2 | collagen beta(1-O)galactosyltransferase 2 |
CST1 | cystatin SN |
CYP20A1 | cytochrome P450, family 20, subfamily A, polypeptide 1 |
DBF4B | DBF4 zinc finger B |
DNAH17 | dynein, axonemal, heavy chain 17 |
ERCC4 | excision repair cross-complementation group 4 |
ERN2 | endoplasmic reticulum to nucleus signaling 2 |
FAM184A | family with sequence similarity 184, member A |
FLT4 | fms-related tyrosine kinase 4 |
GALK1 | galactokinase 1 |
GEMIN8 | gem (nuclear organelle) associated protein 8 |
GIPC1 | GIPC PDZ domain containing family, member 1 |
GRAMD1C | GRAM domain containing 1C |
HCFC2 | host cell factor C2 |
HIST1H2AK | histone cluster 1, H2ak |
HIST1H2AM | histone cluster 1, H2am |
HIST1H3C | histone cluster 1, H3c |
HSPA1L | heat shock 70kDa protein 1-like |
IDI2-AS1 | IDI2 antisense RNA 1 |
IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
IL4R | interleukin 4 receptor |
INO80D | INO80 complex subunit D |
KBTBD4 | kelch repeat and BTB (POZ) domain containing 4 |
KIAA0895 | KIAA0895 |
KIAA1456 | KIAA1456 |
KIF1B | kinesin family member 1B |
LPAR4 | lysophosphatidic acid receptor 4 |
MFSD12 | major facilitator superfamily domain containing 12 |
MGP | matrix Gla protein |
MILR1 | mast cell immunoglobulin-like receptor 1 |
MT1H | metallothionein 1H |
MYOZ3 | myozenin 3 |
NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
NDRG4 | NDRG family member 4 |
NKX3-2 | NK3 homeobox 2 |
NSUN6 | NOP2/Sun domain family, member 6 |
OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
ORAI3 | ORAI calcium release-activated calcium modulator 3 |
OSR2 | odd-skipped related transciption factor 2 |
PARP3 | poly (ADP-ribose) polymerase family, member 3 |
PDE8B | phosphodiesterase 8B |
PICK1 | protein interacting with PRKCA 1 |
PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) |
PLD2 | phospholipase D2 |
PLEKHG6 | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 |
PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
PRF1 | perforin 1 (pore forming protein) |
PRRG2 | proline rich Gla (G-carboxyglutamic acid) 2 |
PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 |
RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
RNF39 | ring finger protein 39 |
SFMBT1 | Scm-like with four mbt domains 1 |
SLC35C2 | solute carrier family 35 (GDP-fucose transporter), member C2 |
SLC46A3 | solute carrier family 46, member 3 |
SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
SP140L | SP140 nuclear body protein-like |
STARD13 | StAR-related lipid transfer (START) domain containing 13 |
STIM1 | stromal interaction molecule 1 |
SYNPO | synaptopodin |
TCTN2 | tectonic family member 2 |
TKFC | triokinase/FMN cyclase |
TMEM183A | transmembrane protein 183A |
TMSB15A | thymosin beta 15a |
TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
TRDMT1 | tRNA aspartic acid methyltransferase 1 |
TRIM45 | tripartite motif containing 45 |
TUBA4B | tubulin, alpha 4b |
ULBP2 | UL16 binding protein 2 |
UNC119 | unc-119 homolog (C. elegans) |
WBP2 | WW domain binding protein 2 |
XYLT2 | xylosyltransferase II |
ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
ZFHX3 | zinc finger homeobox 3 |
ZFP69B | ZFP69 zinc finger protein B |
ZNF141 | zinc finger protein 141 |
ZNF227 | zinc finger protein 227 |
ZNF276 | zinc finger protein 276 |
ZNF282 | zinc finger protein 282 |
ZNF286A | zinc finger protein 286A |
ZNF358 | zinc finger protein 358 |
ZNF37BP | zinc finger protein 37B, pseudogene |
ZNF446 | zinc finger protein 446 |