glaucoma Gene Set

Dataset GWASdb SNP-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/DOID:1686
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Genes

109 genes associated with the disease glaucoma in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.

Symbol Name Standardized Value
LOXL1 lysyl oxidase-like 1 2.22462
PTGER3 prostaglandin E receptor 3 (subtype EP3) 1.96361
CDKN2B-AS1 CDKN2B antisense RNA 1 1.94711
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 1.78926
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 1.69776
PLEKHA7 pleckstrin homology domain containing, family A member 7 1.65612
COL11A1 collagen, type XI, alpha 1 1.51254
CAV2 caveolin 2 1.50593
RERE arginine-glutamic acid dipeptide (RE) repeats 1.481
SRBD1 S1 RNA binding domain 1 1.47287
GAS7 growth arrest-specific 7 1.42467
TMCO1 transmembrane and coiled-coil domains 1 1.39396
ADAMTSL1 ADAMTS-like 1 1.38913
ADAMTS16 ADAM metallopeptidase with thrombospondin type 1 motif, 16 1.35025
SDR9C7 short chain dehydrogenase/reductase family 9C, member 7 1.29807
DCLK3 doublecortin-like kinase 3 1.29473
TXNRD2 thioredoxin reductase 2 1.28906
FAT3 FAT atypical cadherin 3 1.28041
CADPS Ca++-dependent secretion activator 1.22038
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive) 1.21996
PRKCH protein kinase C, eta 1.18698
ZNF827 zinc finger protein 827 1.15017
ITPKB inositol-trisphosphate 3-kinase B 1.14755
SLC30A8 solute carrier family 30 (zinc transporter), member 8 1.14463
PDE7B phosphodiesterase 7B 1.14463
CDKN2A cyclin-dependent kinase inhibitor 2A 1.13453
LOC643339 uncharacterized LOC643339 1.12515
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 1.12515
LRRC4C leucine rich repeat containing 4C 1.12051
CSF1R colony stimulating factor 1 receptor 1.11813
SIX6 SIX homeobox 6 1.1168
PTPRD protein tyrosine phosphatase, receptor type, D 1.11197
BMPR1A bone morphogenetic protein receptor, type IA 1.10764
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 1.10764
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 1.10055
PDE4D phosphodiesterase 4D, cAMP-specific 1.09895
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 1.07599
RGS6 regulator of G-protein signaling 6 1.07108
PLB1 phospholipase B1 1.0675
CPB1 carboxypeptidase B1 (tissue) 1.05742
FOXP1 forkhead box P1 1.04846
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) 1.0358
LOC100147773 uncharacterized LOC100147773 0.996743
ANKRD44 ankyrin repeat domain 44 0.977576
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 0.973451
SATB1 SATB homeobox 1 0.96839
SLC6A5 solute carrier family 6 (neurotransmitter transporter), member 5 0.964504
FOCAD focadhesin 0.958493
AFAP1 actin filament associated protein 1 0.958374
ATOH7 atonal homolog 7 (Drosophila) 0.931906
RCAN2 regulator of calcineurin 2 0.886521
WDR82 WD repeat domain 82 0.875673
FAM169B family with sequence similarity 169, member B 0.855811
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa 0.855811
DSTYK dual serine/threonine and tyrosine protein kinase 0.845188
CRMP1 collapsin response mediator protein 1 0.829434
RPSAP52 ribosomal protein SA pseudogene 52 0.806323
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2) 0.792205
NPAS3 neuronal PAS domain protein 3 0.787593
PARD3B par-3 family cell polarity regulator beta 0.778355
MTAP methylthioadenosine phosphorylase 0.761811
ZDHHC2 zinc finger, DHHC-type containing 2 0.749105
MAML2 mastermind-like 2 (Drosophila) 0.739348
SOD2 superoxide dismutase 2, mitochondrial 0.728903
BRE brain and reproductive organ-expressed (TNFRSF1A modulator) 0.720957
NWD2 NACHT and WD repeat domain containing 2 0.716781
TMTC2 transmembrane and tetratricopeptide repeat containing 2 0.716372
CDH13 cadherin 13 0.700665
LOC729911 0.69773
BBS9 Bardet-Biedl syndrome 9 0.696546
HS6ST3 heparan sulfate 6-O-sulfotransferase 3 0.691778
PXDNL peroxidasin-like 0.691297
CSMD1 CUB and Sushi multiple domains 1 0.679818
MARCH1 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase 0.62609
ZSWIM3 zinc finger, SWIM-type containing 3 0.615118
EBF4 early B-cell factor 4 0.588801
DNTTIP1 deoxynucleotidyltransferase, terminal, interacting protein 1 0.583982
GFAP glial fibrillary acidic protein 0.583062
ATP8B5P ATPase, class I, type 8B, member 5, pseudogene 0.554406
AP1S3 adaptor-related protein complex 1, sigma 3 subunit 0.526189
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.516782
LOC100506532 uncharacterized LOC100506532 0.500649
COL5A1 collagen, type V, alpha 1 0.49065
COL8A2 collagen, type VIII, alpha 2 0.486213
ADPRHL2 ADP-ribosylhydrolase like 2 0.480254
CHEK2 checkpoint kinase 2 0.477278
DCLK1 doublecortin-like kinase 1 0.477278
BCAS3 breast carcinoma amplified sequence 3 0.470241
FNDC3B fibronectin type III domain containing 3B 0.459383
RFTN1 raftlin, lipid raft linker 1 0.456271
MYPN myopalladin 0.456271
AKAP6 A kinase (PRKA) anchor protein 6 0.454317
LRP1B low density lipoprotein receptor-related protein 1B 0.452375
ARID3A AT rich interactive domain 3A (BRIGHT-like) 0.452375
IDO2 indoleamine 2,3-dioxygenase 2 0.450176
FAM53B family with sequence similarity 53, member B 0.447649
TRAPPC3 trafficking protein particle complex 3 0.443353
FAM175B family with sequence similarity 175, member B 0.441647
LINC00290 long intergenic non-protein coding RNA 290 0.435351
SCFD2 sec1 family domain containing 2 0.430311
TSHR thyroid stimulating hormone receptor 0.422054
DENND2A DENN/MADD domain containing 2A 0.422054
RASGRF2 Ras protein-specific guanine nucleotide-releasing factor 2 0.417269
SDK1 sidekick cell adhesion molecule 1 0.416392
ESRRG estrogen-related receptor gamma 0.414949
PEX14 peroxisomal biogenesis factor 14 0.414949
PIAS2 protein inhibitor of activated STAT, 2 0.412143
MYH9 myosin, heavy chain 9, non-muscle 0.411526
CNTNAP2 contactin associated protein-like 2 0.357293