glafenine-7257 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the glafenine-7257 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
AMBRA1 autophagy/beclin-1 regulator 1
AMDHD2 amidohydrolase domain containing 2
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
ANP32A-IT1 ANP32A intronic transcript 1
AP1M2 adaptor-related protein complex 1, mu 2 subunit
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
APC adenomatous polyposis coli
ARHGAP26 Rho GTPase activating protein 26
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
BAIAP2 BAI1-associated protein 2
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BRD4 bromodomain containing 4
BTN3A2 butyrophilin, subfamily 3, member A2
C11ORF30 chromosome 11 open reading frame 30
C1S complement component 1, s subcomponent
CCDC85C coiled-coil domain containing 85C
CCNJ cyclin J
CD52 CD52 molecule
CES2 carboxylesterase 2
CHMP6 charged multivesicular body protein 6
CIB2 calcium and integrin binding family member 2
CISH cytokine inducible SH2-containing protein
CLCN6 chloride channel, voltage-sensitive 6
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CREBZF CREB/ATF bZIP transcription factor
CRELD1 cysteine-rich with EGF-like domains 1
CSF1 colony stimulating factor 1 (macrophage)
DHODH dihydroorotate dehydrogenase (quinone)
DHRS9 dehydrogenase/reductase (SDR family) member 9
EPPK1 epiplakin 1
ERAP2 endoplasmic reticulum aminopeptidase 2
F11R F11 receptor
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FEM1B fem-1 homolog b (C. elegans)
FXYD2 FXYD domain containing ion transport regulator 2
GADD45A growth arrest and DNA-damage-inducible, alpha
GK glycerol kinase
HCRP1 hepatocellular carcinoma-related HCRP1
HHAT hedgehog acyltransferase
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HIST1H1T histone cluster 1, H1t
HIST1H3C histone cluster 1, H3c
IL1R1 interleukin 1 receptor, type I
INCENP inner centromere protein antigens 135/155kDa
IPO8 importin 8
IRF6 interferon regulatory factor 6
IRS2 insulin receptor substrate 2
KAT6A K(lysine) acetyltransferase 6A
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIF5C kinesin family member 5C
KLF2 Kruppel-like factor 2
LIG4 ligase IV, DNA, ATP-dependent
LOC730101 uncharacterized LOC730101
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAP7 microtubule-associated protein 7
MBTD1 mbt domain containing 1
MED13L mediator complex subunit 13-like
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MYO9B myosin IXB
NF1 neurofibromin 1
NXPE3 neurexophilin and PC-esterase domain family, member 3
OASL 2'-5'-oligoadenylate synthetase-like
OTUD3 OTU deubiquitinase 3
PALM paralemmin
PDGFRL platelet-derived growth factor receptor-like
PEX1 peroxisomal biogenesis factor 1
PEX5 peroxisomal biogenesis factor 5
PEX7 peroxisomal biogenesis factor 7
PGAP1 post-GPI attachment to proteins 1
PHLDA3 pleckstrin homology-like domain, family A, member 3
RECQL5 RecQ protein-like 5
RGS4 regulator of G-protein signaling 4
RTEL1 regulator of telomere elongation helicase 1
RUSC2 RUN and SH3 domain containing 2
RWDD3 RWD domain containing 3
SETD6 SET domain containing 6
SFTPB surfactant protein B
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
SGSM3 small G protein signaling modulator 3
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SPG20 spastic paraplegia 20 (Troyer syndrome)
STC1 stanniocalcin 1
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast)
TMEM242 transmembrane protein 242
ULBP2 UL16 binding protein 2
WWC1 WW and C2 domain containing 1
ZC3H7B zinc finger CCCH-type containing 7B
ZMYND8 zinc finger, MYND-type containing 8
ZNF112 zinc finger protein 112
ZNF165 zinc finger protein 165
ZNF34 zinc finger protein 34
ZNF37BP zinc finger protein 37B, pseudogene
ZNF407 zinc finger protein 407

decreased expression

Symbol Name
ACSF2 acyl-CoA synthetase family member 2
ACTG2 actin, gamma 2, smooth muscle, enteric
ADAM15 ADAM metallopeptidase domain 15
AEN apoptosis enhancing nuclease
AFAP1 actin filament associated protein 1
ALDH18A1 aldehyde dehydrogenase 18 family, member A1
ANKFY1 ankyrin repeat and FYVE domain containing 1
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ASB7 ankyrin repeat and SOCS box containing 7
ATAD3A ATPase family, AAA domain containing 3A
ATP13A2 ATPase type 13A2
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BCAS4 breast carcinoma amplified sequence 4
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1
BTBD2 BTB (POZ) domain containing 2
C19ORF40 chromosome 19 open reading frame 40
C7ORF43 chromosome 7 open reading frame 43
CAPN5 calpain 5
CCNO cyclin O
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CIR1 corepressor interacting with RBPJ, 1
CLEC16A C-type lectin domain family 16, member A
CTNNBL1 catenin, beta like 1
EDC3 enhancer of mRNA decapping 3
EVA1B eva-1 homolog B (C. elegans)
FBXO46 F-box protein 46
FHOD1 formin homology 2 domain containing 1
GPRASP1 G protein-coupled receptor associated sorting protein 1
GPS2 G protein pathway suppressor 2
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HAUS7 HAUS augmin-like complex, subunit 7
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
JUNB jun B proto-oncogene
LHFP lipoma HMGIC fusion partner
LSR lipolysis stimulated lipoprotein receptor
LTBP2 latent transforming growth factor beta binding protein 2
LUC7L LUC7-like (S. cerevisiae)
MCMBP minichromosome maintenance complex binding protein
MFSD12 major facilitator superfamily domain containing 12
MICALL2 MICAL-like 2
MMP13 matrix metallopeptidase 13
MNS1 meiosis-specific nuclear structural 1
MYLK myosin light chain kinase
NOL6 nucleolar protein 6 (RNA-associated)
NPR3 natriuretic peptide receptor 3
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3
ODF2 outer dense fiber of sperm tails 2
ORAI3 ORAI calcium release-activated calcium modulator 3
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha
PIGH phosphatidylinositol glycan anchor biosynthesis, class H
PNRC1 proline-rich nuclear receptor coactivator 1
POLA2 polymerase (DNA directed), alpha 2, accessory subunit
PRAME preferentially expressed antigen in melanoma
PRICKLE3 prickle homolog 3 (Drosophila)
RBM42 RNA binding motif protein 42
RCL1 RNA terminal phosphate cyclase-like 1
RNF121 ring finger protein 121
SAMD9 sterile alpha motif domain containing 9
SH2D4A SH2 domain containing 4A
SH3BGR SH3 domain binding glutamate-rich protein
SLC12A8 solute carrier family 12, member 8
SLC22A18 solute carrier family 22, member 18
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SNX24 sorting nexin 24
SP140L SP140 nuclear body protein-like
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
TBC1D19 TBC1 domain family, member 19
THOP1 thimet oligopeptidase 1
TIGD6 tigger transposable element derived 6
TM7SF2 transmembrane 7 superfamily member 2
TMEM120B transmembrane protein 120B
TMEM132A transmembrane protein 132A
TMEM209 transmembrane protein 209
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast)
TOR4A torsin family 4, member A
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TSPAN1 tetraspanin 1
TTC23 tetratricopeptide repeat domain 23
TTC33 tetratricopeptide repeat domain 33
USB1 U6 snRNA biogenesis 1
USP27X ubiquitin specific peptidase 27, X-linked
USP32 ubiquitin specific peptidase 32
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial
ZFP69B ZFP69 zinc finger protein B
ZNF324 zinc finger protein 324
ZNF385D zinc finger protein 385D
ZNF415 zinc finger protein 415
ZNF574 zinc finger protein 574
ZNF804A zinc finger protein 804A