glafenine-7018 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the glafenine-7018 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM17 ADAM metallopeptidase domain 17
ADGRL1 adhesion G protein-coupled receptor L1
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ATG13 autophagy related 13
ATP7B ATPase, Cu++ transporting, beta polypeptide
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
BRD4 bromodomain containing 4
C14ORF105 chromosome 14 open reading frame 105
CASP3 caspase 3, apoptosis-related cysteine peptidase
CBX4 chromobox homolog 4
CCDC25 coiled-coil domain containing 25
CEP72 centrosomal protein 72kDa
CFLAR CASP8 and FADD-like apoptosis regulator
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CLSTN3 calsyntenin 3
COL7A1 collagen, type VII, alpha 1
COMP cartilage oligomeric matrix protein
CTNNBIP1 catenin, beta interacting protein 1
CYLD cylindromatosis (turban tumor syndrome)
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DIO2 deiodinase, iodothyronine, type II
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DNAL4 dynein, axonemal, light chain 4
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DTNA dystrobrevin, alpha
DUSP4 dual specificity phosphatase 4
E2F1 E2F transcription factor 1
EGR1 early growth response 1
ERN2 endoplasmic reticulum to nucleus signaling 2
ESR1 estrogen receptor 1
FAM53B family with sequence similarity 53, member B
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FASTK Fas-activated serine/threonine kinase
FBRS fibrosin
FBXO2 F-box protein 2
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GLS glutaminase
GMIP GEM interacting protein
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GRK4 G protein-coupled receptor kinase 4
IL4R interleukin 4 receptor
IL6R interleukin 6 receptor
INADL InaD-like (Drosophila)
IRS2 insulin receptor substrate 2
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KLF11 Kruppel-like factor 11
LAMP1 lysosomal-associated membrane protein 1
LMCD1 LIM and cysteine-rich domains 1
LRP6 low density lipoprotein receptor-related protein 6
LYRM9 LYR motif containing 9
LZTR1 leucine-zipper-like transcription regulator 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP4 microtubule-associated protein 4
MAST2 microtubule associated serine/threonine kinase 2
MAST4 microtubule associated serine/threonine kinase family member 4
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MGC12488
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MROH9 maestro heat-like repeat family member 9
MTAP methylthioadenosine phosphorylase
MXD4 MAX dimerization protein 4
NDE1 nudE neurodevelopment protein 1
NDRG4 NDRG family member 4
OPRL1 opiate receptor-like 1
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRDM2 PR domain containing 2, with ZNF domain
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRMT2 protein arginine methyltransferase 2
PTAFR platelet-activating factor receptor
PTCRA pre T-cell antigen receptor alpha
PTPRF protein tyrosine phosphatase, receptor type, F
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RANGAP1 Ran GTPase activating protein 1
RUFY2 RUN and FYVE domain containing 2
RUFY3 RUN and FYVE domain containing 3
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SH2B3 SH2B adaptor protein 3
SLC38A7 solute carrier family 38, member 7
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SOX9 SRY (sex determining region Y)-box 9
SPN sialophorin
STAT5B signal transducer and activator of transcription 5B
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TBC1D13 TBC1 domain family, member 13
TRIL TLR4 interactor with leucine-rich repeats
WDTC1 WD and tetratricopeptide repeats 1
WEE1 WEE1 G2 checkpoint kinase
ZNF440 zinc finger protein 440
ZNF701 zinc finger protein 701
ZNF778 zinc finger protein 778

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ABHD14A abhydrolase domain containing 14A
ACYP2 acylphosphatase 2, muscle type
ADAM15 ADAM metallopeptidase domain 15
AKR1C3 aldo-keto reductase family 1, member C3
ASPHD1 aspartate beta-hydroxylase domain containing 1
C10ORF88 chromosome 10 open reading frame 88
C17ORF62 chromosome 17 open reading frame 62
C21ORF91 chromosome 21 open reading frame 91
C5ORF45 chromosome 5 open reading frame 45
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CCDC15 coiled-coil domain containing 15
CCNO cyclin O
CD151 CD151 molecule (Raph blood group)
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CIDEC cell death-inducing DFFA-like effector c
CLSPN claspin
COCH cochlin
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DHRS11 dehydrogenase/reductase (SDR family) member 11
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
EFNA3 ephrin-A3
ERI3 ERI1 exoribonuclease family member 3
FAM63A family with sequence similarity 63, member A
FANCE Fanconi anemia, complementation group E
FKBP5 FK506 binding protein 5
GALK1 galactokinase 1
GDAP2 ganglioside induced differentiation associated protein 2
GNA13 guanine nucleotide binding protein (G protein), alpha 13
HELZ helicase with zinc finger
HOXB7 homeobox B7
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
IRAK4 interleukin-1 receptor-associated kinase 4
IREB2 iron-responsive element binding protein 2
KLC2 kinesin light chain 2
KLF3 Kruppel-like factor 3 (basic)
LPGAT1 lysophosphatidylglycerol acyltransferase 1
METTL16 methyltransferase like 16
MOCS3 molybdenum cofactor synthesis 3
NAIP NLR family, apoptosis inhibitory protein
NECAP2 NECAP endocytosis associated 2
NPY1R neuropeptide Y receptor Y1
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PDZK1 PDZ domain containing 1
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PLEK2 pleckstrin 2
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
RAB35 RAB35, member RAS oncogene family
RAB5C RAB5C, member RAS oncogene family
RABL6 RAB, member RAS oncogene family-like 6
RBL1 retinoblastoma-like 1
RBM41 RNA binding motif protein 41
RECQL4 RecQ protein-like 4
REPS2 RALBP1 associated Eps domain containing 2
RIBC2 RIB43A domain with coiled-coils 2
RLN2 relaxin 2
RPL13P5 ribosomal protein L13 pseudogene 5
RPUSD2 RNA pseudouridylate synthase domain containing 2
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
S100A4 S100 calcium binding protein A4
SGK1 serum/glucocorticoid regulated kinase 1
SHPK sedoheptulokinase
SLC12A8 solute carrier family 12, member 8
SLC12A9 solute carrier family 12, member 9
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC35D2 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
SLC46A3 solute carrier family 46, member 3
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SOX3 SRY (sex determining region Y)-box 3
SPINK4 serine peptidase inhibitor, Kazal type 4
SYBU syntabulin (syntaxin-interacting)
SYF2 SYF2 pre-mRNA-splicing factor
TCTA T-cell leukemia translocation altered
TEAD3 TEA domain family member 3
THBS3 thrombospondin 3
TMEM62 transmembrane protein 62
TRAPPC13 trafficking protein particle complex 13
TRIM5 tripartite motif containing 5
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TTC17 tetratricopeptide repeat domain 17
TUBA3D tubulin, alpha 3d
URM1 ubiquitin related modifier 1
USP18 ubiquitin specific peptidase 18
ZBTB25 zinc finger and BTB domain containing 25
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF180 zinc finger protein 180
ZNF248 zinc finger protein 248
ZNF268 zinc finger protein 268
ZNF443 zinc finger protein 443
ZNF586 zinc finger protein 586