giant cell tumor Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

197 genes co-occuring with the disease giant cell tumor in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
CD68 CD68 molecule 1.7727
ACPP acid phosphatase, prostate 1.67503
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A 1.38778
CALCA calcitonin-related polypeptide alpha 1.36161
USP6 ubiquitin specific peptidase 6 1.34374
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 1.3027
CSF1 colony stimulating factor 1 (macrophage) 1.26386
CSF1R colony stimulating factor 1 receptor 1.17121
CTSK cathepsin K 1.10468
PTH parathyroid hormone 1.0463
TP53 tumor protein p53 1.0303
LYZ lysozyme 1.01638
SH3BP2 SH3-domain binding protein 2 1.00541
SEBOX SEBOX homeobox 0.97254
CALCR calcitonin receptor 0.964567
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.961634
PGM1 phosphoglucomutase 1 0.94078
CD163 CD163 molecule 0.926279
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 0.870415
ALPPL2 alkaline phosphatase, placental-like 2 0.862228
ALPP alkaline phosphatase, placental 0.861409
ALPL alkaline phosphatase, liver/bone/kidney 0.860999
TRBC1 T cell receptor beta constant 1 0.836427
IBSP integrin-binding sialoprotein 0.829869
CLEC2D C-type lectin domain family 2, member D 0.800744
RGS12 regulator of G-protein signaling 12 0.798282
PTPRC protein tyrosine phosphatase, receptor type, C 0.788033
CTSS cathepsin S 0.771252
FLRT2 fibronectin leucine rich transmembrane protein 2 0.762678
BGLAP bone gamma-carboxyglutamate (gla) protein 0.761454
DNAH8 dynein, axonemal, heavy chain 8 0.760639
ZNF133 zinc finger protein 133 0.749644
SIGLEC15 sialic acid binding Ig-like lectin 15 0.743954
COL6A3 collagen, type VI, alpha 3 0.739082
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.723694
NT5M 5',3'-nucleotidase, mitochondrial 0.686291
ADAM12 ADAM metallopeptidase domain 12 0.681495
P2RY2 purinergic receptor P2Y, G-protein coupled, 2 0.677903
PTHLH parathyroid hormone-like hormone 0.675909
MMP13 matrix metallopeptidase 13 0.66596
ONECUT2 one cut homeobox 2 0.661197
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 0.658026
ENO2 enolase 2 (gamma, neuronal) 0.654463
SPP1 secreted phosphoprotein 1 0.643797
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator 0.632777
RUNX2 runt-related transcription factor 2 0.625319
FGF23 fibroblast growth factor 23 0.615529
CD34 CD34 molecule 0.60342
PCNA proliferating cell nuclear antigen 0.597181
TES testin LIM domain protein 0.587054
MMP9 matrix metallopeptidase 9 0.587054
CA2 carbonic anhydrase II 0.586276
ACP5 acid phosphatase 5, tartrate resistant 0.575772
AHCYL1 adenosylhomocysteinase-like 1 0.574605
ADAM8 ADAM metallopeptidase domain 8 0.571107
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 0.568775
CALD1 caldesmon 1 0.563335
THBS3 thrombospondin 3 0.562558
SLMAP sarcolemma associated protein 0.541217
GUSB glucuronidase, beta 0.532314
GFAP glial fibrillary acidic protein 0.529222
TUBA1C tubulin, alpha 1c 0.524974
NF1 neurofibromin 1 0.51611
FN1 fibronectin 1 0.515725
AURKB aurora kinase B 0.505739
API5 apoptosis inhibitor 5 0.456732
TXNRD2 thioredoxin reductase 2 0.431519
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa 0.427765
KRAS Kirsten rat sarcoma viral oncogene homolog 0.41465
THRA thyroid hormone receptor, alpha 0.413901
HRAS Harvey rat sarcoma viral oncogene homolog 0.411283
PTH1R parathyroid hormone 1 receptor 0.410535
TUBB2A tubulin, beta 2A class IIa 0.405678
TGFB2 transforming growth factor, beta 2 0.399334
CTSL cathepsin L 0.393746
DIO3 deiodinase, iodothyronine, type III 0.385936
BUB3 BUB3 mitotic checkpoint protein 0.385565
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.379256
TUBB tubulin, beta class I 0.369258
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.36741
GRM8 glutamate receptor, metabotropic 8 0.363716
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 0.363716
TGFB1 transforming growth factor, beta 1 0.362609
CXXC5 CXXC finger protein 5 0.359289
PLAU plasminogen activator, urokinase 0.350084
SYP synaptophysin 0.346409
MMP2 matrix metallopeptidase 2 0.343473
LCK LCK proto-oncogene, Src family tyrosine kinase 0.343106
PDPN podoplanin 0.342739
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.342006
AMT aminomethyltransferase 0.33651
CDKN2A cyclin-dependent kinase inhibitor 2A 0.331756
SLC25A18 solute carrier family 25 (glutamate carrier), member 18 0.328834
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.325916
CCL23 chemokine (C-C motif) ligand 23 0.321909
H3F3B H3 histone, family 3B (H3.3B) 0.320817
H3F3A H3 histone, family 3A 0.320817
MRC1 mannose receptor, C type 1 0.318635
IL6 interleukin 6 0.31029
ADCY1 adenylate cyclase 1 (brain) 0.309204
BMP5 bone morphogenetic protein 5 0.302337
ACP2 acid phosphatase 2, lysosomal 0.299092
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.296211
IL1B interleukin 1, beta 0.286877
MET MET proto-oncogene, receptor tyrosine kinase 0.28616
NT5E 5'-nucleotidase, ecto (CD73) 0.284371
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.283297
S100A9 S100 calcium binding protein A9 0.279011
IGFBP4 insulin-like growth factor binding protein 4 0.275801
SQSTM1 sequestosome 1 0.272241
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.257005
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 0.256652
TWIST1 twist family bHLH transcription factor 1 0.255946
TERF2 telomeric repeat binding factor 2 0.252422
MKI67 marker of proliferation Ki-67 0.251718
ADAM28 ADAM metallopeptidase domain 28 0.251015
POT1 protection of telomeres 1 0.241895
CCND1 cyclin D1 0.241895
F8 coagulation factor VIII, procoagulant component 0.240497
FOS FBJ murine osteosarcoma viral oncogene homolog 0.237357
VCL vinculin 0.228333
YES1 YES proto-oncogene 1, Src family tyrosine kinase 0.226607
MON1A MON1 secretory trafficking family member A 0.217352
PDXK pyridoxal (pyridoxine, vitamin B6) kinase 0.20658
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 0.204593
FABP3 fatty acid binding protein 3, muscle and heart 0.202618
CYS1 cystin 1 0.20229
TPRG1L tumor protein p63 regulated 1-like 0.201635
GRM4 glutamate receptor, metabotropic 4 0.201635
TGFB3 transforming growth factor, beta 3 0.200006
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.19582
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase 0.194232
CCR1 chemokine (C-C motif) receptor 1 0.1936
SMAD5 SMAD family member 5 0.190476
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.183541
MEPE matrix extracellular phosphoglycoprotein 0.183248
ATP11A ATPase, class VI, type 11A 0.180367
S100A10 S100 calcium binding protein A10 0.179239
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.174354
MITF microphthalmia-associated transcription factor 0.173057
TERT telomerase reverse transcriptase 0.171286
IGF1 insulin-like growth factor 1 (somatomedin C) 0.169571
TPP1 tripeptidyl peptidase I 0.168148
EFNA1 ephrin-A1 0.166768
CCND3 cyclin D3 0.166095
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 0.164359
CTSB cathepsin B 0.164149
AIF1 allograft inflammatory factor 1 0.163938
ITGAV integrin, alpha V 0.163111
VIM vimentin 0.163111
TPX2 TPX2, microtubule-associated 0.161716
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.160021
MYOG myogenin (myogenic factor 4) 0.158097
BSG basigin (Ok blood group) 0.157765
GCGR glucagon receptor 0.140276
MSX1 msh homeobox 1 0.139724
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 0.135933
CCNB1 cyclin B1 0.134566
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.134399
S100P S100 calcium binding protein P 0.134057
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 0.133084
LMO2 LIM domain only 2 (rhombotin-like 1) 0.132204
PTEN phosphatase and tensin homolog 0.131557
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide 0.129019
AMD1 adenosylmethionine decarboxylase 1 0.128472
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 0.12744
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.12445
CXCL13 chemokine (C-X-C motif) ligand 13 0.124362
S100A8 S100 calcium binding protein A8 0.123247
EGFR epidermal growth factor receptor 0.120672
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 0.119303
FGF3 fibroblast growth factor 3 0.119156
ALCAM activated leukocyte cell adhesion molecule 0.117716
SFRP4 secreted frizzled-related protein 4 0.116183
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 0.115583
PTER phosphotriesterase related 0.115448
THBS1 thrombospondin 1 0.114761
MYOD1 myogenic differentiation 1 0.114658
CXCL12 chemokine (C-X-C motif) ligand 12 0.114551
HMGA2 high mobility group AT-hook 2 0.114303
TERF1 telomeric repeat binding factor (NIMA-interacting) 1 0.113296
KRT8 keratin 8, type II 0.113077
FRZB frizzled-related protein 0.111564
EWSR1 EWS RNA-binding protein 1 0.111293
NFIB nuclear factor I/B 0.111138
CALB2 calbindin 2 0.110742
PRRC2A proline-rich coiled-coil 2A 0.110144
DLK1 delta-like 1 homolog (Drosophila) 0.109817
TNC tenascin C 0.109571
CCL8 chemokine (C-C motif) ligand 8 0.109243
CASP6 caspase 6, apoptosis-related cysteine peptidase 0.108446
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 0.106492
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 0.106492
IL1R1 interleukin 1 receptor, type I 0.105958
CASR calcium-sensing receptor 0.105228
HK2 hexokinase 2 0.10416
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 0.101901