gestational trophoblastic neoplasm Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description OMIM mapping confirmed by DO. [SN]. (Human Disease Ontology, DOID_3590)
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Genes

167 genes co-occuring with the disease gestational trophoblastic neoplasm in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
NLRP7 NLR family, pyrin domain containing 7 2.47948
KHDC3L KH domain containing 3-like, subcortical maternal complex member 1.908
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 1.87056
CSH2 chorionic somatomammotropin hormone 2 1.816
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen) 1.75278
CTSC cathepsin C 1.7159
PSG9 pregnancy specific beta-1-glycoprotein 9 1.46232
NR0B1 nuclear receptor subfamily 0, group B, member 1 1.43244
NLRP2 NLR family, pyrin domain containing 2 1.26516
PHLDA2 pleckstrin homology-like domain, family A, member 2 1.18367
LGALS1 lectin, galactoside-binding, soluble, 1 1.16179
STARD7 StAR-related lipid transfer (START) domain containing 7 1.15709
ZC2HC1B zinc finger, C2HC-type containing 1B 1.14815
TFPI2 tissue factor pathway inhibitor 2 1.13839
RNF130 ring finger protein 130 1.13078
PLEKHH1 pleckstrin homology domain containing, family H (with MyTH4 domain) member 1 1.13078
PSG1 pregnancy specific beta-1-glycoprotein 1 1.09965
INHA inhibin, alpha 1.08412
AFP alpha-fetoprotein 0.986428
PAEP progestagen-associated endometrial protein 0.935385
ARFGAP2 ADP-ribosylation factor GTPase activating protein 2 0.888029
PSG6 pregnancy specific beta-1-glycoprotein 6 0.874509
SNTG1 syntrophin, gamma 1 0.831099
MCM7 minichromosome maintenance complex component 7 0.826178
CGB chorionic gonadotropin, beta polypeptide 0.819616
CGB8 chorionic gonadotropin, beta polypeptide 8 0.819206
PSG2 pregnancy specific beta-1-glycoprotein 2 0.816334
ERV3-1 endogenous retrovirus group 3, member 1 0.806898
LIG3 ligase III, DNA, ATP-dependent 0.802795
NLRP5 NLR family, pyrin domain containing 5 0.775341
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1 0.724502
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 0.723694
CLIC1 chloride intracellular channel 1 0.720865
FRRS1L ferric-chelate reductase 1-like 0.716425
MMP12 matrix metallopeptidase 12 0.706754
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A 0.70233
TP53 tumor protein p53 0.681096
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2 0.675112
GH2 growth hormone 2 0.672324
PLAGL1 pleiomorphic adenoma gene-like 1 0.667947
HSPE1 heat shock 10kDa protein 1 0.658818
MAS1 MAS1 proto-oncogene, G protein-coupled receptor 0.648138
PSG5 pregnancy specific beta-1-glycoprotein 5 0.633956
ZFP57 ZFP57 zinc finger protein 0.620226
SGCE sarcoglycan, epsilon 0.61162
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A 0.60303
KIF7 kinesin family member 7 0.578494
HAS1 hyaluronan synthase 1 0.573828
PCTP phosphatidylcholine transfer protein 0.572273
KISS1 KiSS-1 metastasis-suppressor 0.554403
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 0.554015
EBAG9 estrogen receptor binding site associated, antigen, 9 0.548195
MIB1 mindbomb E3 ubiquitin protein ligase 1 0.542379
TLE4 transducin-like enhancer of split 4 0.531541
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3 0.524202
TRH thyrotropin-releasing hormone 0.518034
ELAVL3 ELAV like neuron-specific RNA binding protein 3 0.502292
HMP19 HMP19 protein 0.502292
HLA-A major histocompatibility complex, class I, A 0.499997
CSHL1 chorionic somatomammotropin hormone-like 1 0.499231
PGF placental growth factor 0.483985
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 0.475634
MEFV Mediterranean fever 0.469954
SNRPN small nuclear ribonucleoprotein polypeptide N 0.468063
IGFBP1 insulin-like growth factor binding protein 1 0.460129
PRL prolactin 0.457864
SDC3 syndecan 3 0.452208
CAPN1 calpain 1, (mu/I) large subunit 0.449571
IGF2 insulin-like growth factor 2 0.448064
MMP23B matrix metallopeptidase 23B 0.447311
RASA1 RAS p21 protein activator (GTPase activating protein) 1 0.441666
PZP pregnancy-zone protein 0.435275
DUOXA1 dual oxidase maturation factor 1 0.433397
SYN2 synapsin II 0.426265
GALP galanin-like peptide 0.423265
RHCE Rh blood group, CcEe antigens 0.416896
USP1 ubiquitin specific peptidase 1 0.406425
F2R coagulation factor II (thrombin) receptor 0.401572
PROK1 prokineticin 1 0.395235
CTNNA3 catenin (cadherin-associated protein), alpha 3 0.394118
FOXJ1 forkhead box J1 0.379997
DNMT3L DNA (cytosine-5-)-methyltransferase 3-like 0.377773
TMEM245 transmembrane protein 245 0.37629
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4 0.37555
ANOS1 anosmin 1 0.375179
ERBB2 erb-b2 receptor tyrosine kinase 2 0.372958
RNH1 ribonuclease/angiogenin inhibitor 1 0.357446
FASLG Fas ligand (TNF superfamily, member 6) 0.355604
GPC1 glypican 1 0.342006
NMS neuromedin S 0.338707
SYN3 synapsin III 0.338707
ZNF436 zinc finger protein 436 0.336144
PEG3 paternally expressed 3 0.335412
BTG2 BTG family, member 2 0.334681
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.332487
PALLD palladin, cytoskeletal associated protein 0.320817
PCNA proliferating cell nuclear antigen 0.318635
LNPEP leucyl/cystinyl aminopeptidase 0.313915
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 0.310652
RAET1E retinoic acid early transcript 1E 0.306672
PI3 peptidase inhibitor 3, skin-derived 0.306672
SHF Src homology 2 domain containing F 0.305948
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.305948
KRT7 keratin 7, type II 0.303059
RHD Rh blood group, D antigen 0.295492
LGALS7 lectin, galactoside-binding, soluble, 7 0.294053
PAPPA pregnancy-associated plasma protein A, pappalysin 1 0.287952
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 0.286519
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 0.275801
POLL polymerase (DNA directed), lambda 0.274732
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4 0.269753
KISS1R KISS1 receptor 0.264785
CGB7 chorionic gonadotropin, beta polypeptide 7 0.261952
CGB5 chorionic gonadotropin, beta polypeptide 5 0.260538
HLA-G major histocompatibility complex, class I, G 0.255594
FANCB Fanconi anemia, complementation group B 0.254888
CDKN2A cyclin-dependent kinase inhibitor 2A 0.252774
RRM2 ribonucleotide reductase M2 0.251015
RFC2 replication factor C (activator 1) 2, 40kDa 0.249608
CSF1R colony stimulating factor 1 receptor 0.249257
ALPPL2 alkaline phosphatase, placental-like 2 0.245396
ALPP alkaline phosphatase, placental 0.245046
ALPL alkaline phosphatase, liver/bone/kidney 0.244345
PEG10 paternally expressed 10 0.243995
ESD esterase D 0.23945
SLC22A18 solute carrier family 22, member 18 0.23945
GH1 growth hormone 1 0.233878
TIMP2 TIMP metallopeptidase inhibitor 2 0.231102
FOXD3 forkhead box D3 0.230755
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.228679
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit 0.228333
PGM1 phosphoglucomutase 1 0.228333
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.228333
IGFBP7 insulin-like growth factor binding protein 7 0.227642
ZNF185 zinc finger protein 185 (LIM domain) 0.22145
HBA1 hemoglobin, alpha 1 0.218374
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 0.210253
DCN decorin 0.202618
HBA2 hemoglobin, alpha 2 0.199356
ROM1 retinal outer segment membrane protein 1 0.198709
IL2 interleukin 2 0.195501
ANGPT2 angiopoietin 2 0.192657
MMP2 matrix metallopeptidase 2 0.192031
ENPEP glutamyl aminopeptidase (aminopeptidase A) 0.190168
EED embryonic ectoderm development 0.189244
HIC1 hypermethylated in cancer 1 0.18651
ANGPT1 angiopoietin 1 0.18591
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 0.18591
KRT18 keratin 18, type I 0.185612
SH2B3 SH2B adaptor protein 3 0.184424
NEFL neurofilament, light polypeptide 0.182375
ADAM12 ADAM metallopeptidase domain 12 0.181798
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.177029
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 0.176485
NANOG Nanog homeobox 0.174093
HSD17B1P1 hydroxysteroid (17-beta) dehydrogenase 1 pseudogene 1 0.173057
LAP3 leucine aminopeptidase 3 0.172544
ST14 suppression of tumorigenicity 14 (colon carcinoma) 0.168854
MMP9 matrix metallopeptidase 9 0.168617
CD34 CD34 molecule 0.165655
LEP leptin 0.164359
HPN hepsin 0.162109
CD68 CD68 molecule 0.160387
STAT2 signal transducer and activator of transcription 2, 113kDa 0.159838
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 0.15948
F8 coagulation factor VIII, procoagulant component 0.158951
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.158434