germ plasm Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description Differentiated cytoplasm associated with a pole of an oocyte, egg or early embryo that will be inherited by the cells that will give rise to the germ line. (Gene Ontology, GO_0060293)
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Genes

239 proteins co-occuring with the germ plasm cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 1.90216
SRA1 steroid receptor RNA activator 1 1.78058
TDRD1 tudor domain containing 1 1.56788
PIWIL1 piwi-like RNA-mediated gene silencing 1 1.54687
NANOS1 nanos homolog 1 (Drosophila) 1.53557
TDRD7 tudor domain containing 7 1.44968
PMS2P1 postmeiotic segregation increased 2 pseudogene 1 1.41867
CHMP2A charged multivesicular body protein 2A 1.36527
TDRD5 tudor domain containing 5 1.35156
PIWIL4 piwi-like RNA-mediated gene silencing 4 1.32438
NANOS3 nanos homolog 3 (Drosophila) 1.25443
BRIX1 BRX1, biogenesis of ribosomes 1.20035
GRIP2 glutamate receptor interacting protein 2 1.17517
BOLL boule-like RNA-binding protein 1.15109
DAZL deleted in azoospermia-like 1.13625
TEF thyrotrophic embryonic factor 1.11786
TDRD9 tudor domain containing 9 1.06094
GYPE glycophorin E (MNS blood group) 1.05438
MAEL maelstrom spermatogenic transposon silencer 1.03579
SUB1 SUB1 homolog (S. cerevisiae) 1.00005
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38 0.959748
TDRD6 tudor domain containing 6 0.949713
CST7 cystatin F (leukocystatin) 0.933601
SRSF10 serine/arginine-rich splicing factor 10 0.931245
ZNF644 zinc finger protein 644 0.927952
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 0.912977
ENO3 enolase 3 (beta, muscle) 0.912045
EPG5 ectopic P-granules autophagy protein 5 homolog (C. elegans) 0.908785
TES testin LIM domain protein 0.90646
STAU1 staufen double-stranded RNA binding protein 1 0.902281
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 0.883321
EXD2 exonuclease 3'-5' domain containing 2 0.870885
TDRKH tudor and KH domain containing 0.863988
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B 0.856635
EIF4E eukaryotic translation initiation factor 4E 0.849746
GBX1 gastrulation brain homeobox 1 0.833679
HIATL1 hippocampus abundant transcript-like 1 0.833679
NSA2 NSA2 ribosome biogenesis homolog (S. cerevisiae) 0.804313
TMEM259 transmembrane protein 259 0.79148
BANK1 B-cell scaffold protein with ankyrin repeats 1 0.745929
NSUN5 NOP2/Sun domain family, member 5 0.736014
TRIM36 tripartite motif containing 36 0.709693
ANKRD49 ankyrin repeat domain 49 0.70439
GMCL1 germ cell-less, spermatogenesis associated 1 0.695587
CLP1 cleavage and polyadenylation factor I subunit 1 0.678543
GRIA3 glutamate receptor, ionotropic, AMPA 3 0.672026
DND1 DND microRNA-mediated repression inhibitor 1 0.64958
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1 0.641858
FADS3 fatty acid desaturase 3 0.631171
PDE1B phosphodiesterase 1B, calmodulin-dependent 0.627335
GLI1 GLI family zinc finger 1 0.627335
PCDHGA10 protocadherin gamma subfamily A, 10 0.621804
POLR1C polymerase (RNA) I polypeptide C, 30kDa 0.621804
DDX25 DEAD (Asp-Glu-Ala-Asp) box helicase 25 0.620954
FANCD2 Fanconi anemia, complementation group D2 0.601066
POC1A POC1 centriolar protein A 0.600223
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 0.59896
TMEM11 transmembrane protein 11 0.597276
PGM3 phosphoglucomutase 3 0.593912
TCL1B T-cell leukemia/lymphoma 1B 0.593492
UBE2D3 ubiquitin-conjugating enzyme E2D 3 0.589714
MAGOHB mago-nashi homolog B (Drosophila) 0.587199
ZNRD1 zinc ribbon domain containing 1 0.585942
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1 0.58134
MAGOH mago-nashi homolog, proliferation-associated (Drosophila) 0.580922
BRSK1 BR serine/threonine kinase 1 0.576747
CSN1S1 casein alpha s1 0.574662
ALG3 ALG3, alpha-1,3- mannosyltransferase 0.566754
ALLC allantoicase 0.566754
MON2 MON2 homolog (S. cerevisiae) 0.562602
ARL6IP4 ADP-ribosylation factor-like 6 interacting protein 4 0.560114
AP1G2 adaptor-related protein complex 1, gamma 2 subunit 0.557629
LOX lysyl oxidase 0.54936
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 0.544411
MAGEE1 melanoma antigen family E1 0.536183
DCP1A decapping mRNA 1A 0.527979
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) 0.524294
TRIM44 tripartite motif containing 44 0.52225
BATF2 basic leucine zipper transcription factor, ATF-like 2 0.509604
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide 0.503506
HN1L hematological and neurological expressed 1-like 0.499447
SSPN sarcospan 0.492561
CER1 cerberus 1, DAN family BMP antagonist 0.490135
NOL9 nucleolar protein 9 0.488115
FBXO44 F-box protein 44 0.484483
PODN podocan 0.48005
PRG1 p53-responsive gene 1 0.471208
CAPN1 calpain 1, (mu/I) large subunit 0.468401
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 0.463198
GYLTL1B glycosyltransferase-like 1B 0.461599
NME1-NME2 NME1-NME2 readthrough 0.458006
MGAM maltase-glucoamylase 0.457208
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 0.453223
WNT11 wingless-type MMTV integration site family, member 11 0.451631
RSPH6A radial spoke head 6 homolog A (Chlamydomonas) 0.45004
ALDH4A1 aldehyde dehydrogenase 4 family, member A1 0.45004
PGD phosphogluconate dehydrogenase 0.448054
FADS2 fatty acid desaturase 2 0.4425
RPLP1 ribosomal protein, large, P1 0.438146
FOXG1 forkhead box G1 0.437751
MYB v-myb avian myeloblastosis viral oncogene homolog 0.434196
KRTAP1-3 keratin associated protein 1-3 0.431041
ELOVL5 ELOVL fatty acid elongase 5 0.427497
LRRC25 leucine rich repeat containing 25 0.425531
ZAR1 zygote arrest 1 0.41886
PRMT5 protein arginine methyltransferase 5 0.41143
MEI1 meiosis inhibitor 1 0.409479
KIN Kin17 DNA and RNA binding protein 0.409089
FAF2 Fas associated factor family member 2 0.40675
RBM8A RNA binding motif protein 8A 0.403248
SYN3 synapsin III 0.401304
AKTIP AKT interacting protein 0.399363
SSR2 signal sequence receptor, beta (translocon-associated protein beta) 0.398975
PPCS phosphopantothenoylcysteine synthetase 0.395485
ABI3 ABI family, member 3 0.39471
DAZ2 deleted in azoospermia 2 0.393162
GGT2 gamma-glutamyltransferase 2 0.392388
DAZ1 deleted in azoospermia 1 0.390455
KIF13B kinesin family member 13B 0.389296
KRTAP1-1 keratin associated protein 1-1 0.387751
BIN2 bridging integrator 2 0.386593
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 0.385051
TPRG1L tumor protein p63 regulated 1-like 0.385051
VIT vitrin 0.384665
WDR77 WD repeat domain 77 0.384665
PIGC phosphatidylinositol glycan anchor biosynthesis, class C 0.381969
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 0.378507
ANGPTL6 angiopoietin-like 6 0.374666
PDCD11 programmed cell death 11 0.369684
DPEP1 dipeptidase 1 (renal) 0.363949
THUMPD1 THUMP domain containing 1 0.362422
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 0.362422
EPRS glutamyl-prolyl-tRNA synthetase 0.360133
NOP2 NOP2 nucleolar protein 0.359371
SPEG SPEG complex locus 0.358609
FST follistatin 0.358228
PGM1 phosphoglucomutase 1 0.357847
RSPH4A radial spoke head 4 homolog A (Chlamydomonas) 0.357086
SLC1A7 solute carrier family 1 (glutamate transporter), member 7 0.351382
KRT84 keratin 84, type II 0.350622
RGMB repulsive guidance molecule family member b 0.348725
BIN3 bridging integrator 3 0.347967
TMC1 transmembrane channel-like 1 0.341151
POP4 processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae) 0.336241
NME2 NME/NM23 nucleoside diphosphate kinase 2 0.335487
AXIN2 axin 2 0.333979
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24 0.331342
GFRA1 GDNF family receptor alpha 1 0.329837
PRM1 protamine 1 0.323075
MATK megakaryocyte-associated tyrosine kinase 0.317082
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 0.30924
VRK1 vaccinia related kinase 1 0.305515
FEV FEV (ETS oncogene family) 0.303655
DICER1 dicer 1, ribonuclease type III 0.298455
DLK1 delta-like 1 homolog (Drosophila) 0.29586
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.294748
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1 0.290308
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 0.286983
XRN1 5'-3' exoribonuclease 1 0.286245
RTN3 reticulon 3 0.280349
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 0.278877
BCAT2 branched chain amino-acid transaminase 2, mitochondrial 0.278509
PNMA1 paraneoplastic Ma antigen 1 0.277406
FOXH1 forkhead box H1 0.276304
ANTXR2 anthrax toxin receptor 2 0.276304
TUBB2A tubulin, beta 2A class IIa 0.275936
BCAT1 branched chain amino-acid transaminase 1, cytosolic 0.268969
TECR trans-2,3-enoyl-CoA reductase 0.267505
A2M alpha-2-macroglobulin 0.267139
WDR20 WD repeat domain 20 0.26166
CIRBP cold inducible RNA binding protein 0.261296
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.25438
MIER1 mesoderm induction early response 1, transcriptional regulator 0.254017
RPL12 ribosomal protein L12 0.251114
CBS cystathionine-beta-synthase 0.24894
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) 0.246769
LRP5 low density lipoprotein receptor-related protein 5 0.243879
AMT aminomethyltransferase 0.242797
ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide 0.242797
MACF1 microtubule-actin crosslinking factor 1 0.239197
ACP1 acid phosphatase 1, soluble 0.238837
MAST4 microtubule associated serine/threonine kinase family member 4 0.238837
ICT1 immature colon carcinoma transcript 1 0.23776
MMP10 matrix metallopeptidase 10 0.231315
MAT1A methionine adenosyltransferase I, alpha 0.230601
COMT catechol-O-methyltransferase 0.228819
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 0.226686
ELAVL2 ELAV like neuron-specific RNA binding protein 2 0.225622
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 0.22279
DCP2 decapping mRNA 2 0.221025
CASD1 CAS1 domain containing 1 0.219969
PDS5B PDS5 cohesin associated factor B 0.219265
NR6A1 nuclear receptor subfamily 6, group A, member 1 0.217511
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.21681
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 0.21124
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 0.210894
TUBB tubulin, beta class I 0.204718
RAG2 recombination activating gene 2 0.203699
MPI mannose phosphate isomerase 0.203022
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.203022
CAT catalase 0.201335
DDX20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 0.200328
RHOA ras homolog family member A 0.200328
ZNF185 zinc finger protein 185 (LIM domain) 0.198325
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.198325
RPL32 ribosomal protein L32 0.194045
FOXL2 forkhead box L2 0.194045
EPGN epithelial mitogen 0.194045
GGT1 gamma-glutamyltransferase 1 0.19307
DEFB1 defensin, beta 1 0.192746
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2 0.192423
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1 0.192423
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 0.191456
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 0.188905
LPIN1 lipin 1 0.186397
ASNS asparagine synthetase (glutamine-hydrolyzing) 0.184853
MAN2B1 mannosidase, alpha, class 2B, member 1 0.183328
TNP1 transition protein 1 (during histone to protamine replacement) 0.183025
NBR1 neighbor of BRCA1 gene 1 0.181227
NMS neuromedin S 0.177724
C6ORF25 chromosome 6 open reading frame 25 0.17687
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial 0.173814
CTSA cathepsin A 0.17141
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 0.171149
PDCL phosducin-like 0.169099
ACACB acetyl-CoA carboxylase beta 0.168349
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 0.168101
SRR serine racemase 0.167366
RFXANK regulatory factor X-associated ankyrin-containing protein 0.165463
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit 0.164089
RAG1 recombination activating gene 1 0.16298
CWC15 CWC15 spliceosome-associated protein 0.161693
TUB tubby bipartite transcription factor 0.161693
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 0.161068
ERF Ets2 repressor factor 0.160053
WDR5 WD repeat domain 5 0.159856
PRM2 protamine 2 0.159462
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.158692
TGM4 transglutaminase 4 0.156863