genistein-6994 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the genistein-6994 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADCK4 aarF domain containing kinase 4
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
APLP1 amyloid beta (A4) precursor-like protein 1
ASPH aspartate beta-hydroxylase
ASPHD1 aspartate beta-hydroxylase domain containing 1
AUTS2 autism susceptibility candidate 2
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BDKRB1 bradykinin receptor B1
BPY2 basic charge, Y-linked, 2
CAMTA1 calmodulin binding transcription activator 1
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CD53 CD53 molecule
COL8A1 collagen, type VIII, alpha 1
CRYBG3 beta-gamma crystallin domain containing 3
CTSS cathepsin S
CXORF21 chromosome X open reading frame 21
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
EGR3 early growth response 3
ESRRA estrogen-related receptor alpha
FAM13C family with sequence similarity 13, member C
FAM189A2 family with sequence similarity 189, member A2
FER fer (fps/fes related) tyrosine kinase
FGFR1 fibroblast growth factor receptor 1
FYB FYN binding protein
GAS6 growth arrest-specific 6
GATA4 GATA binding protein 4
GJB3 gap junction protein, beta 3, 31kDa
GLRX glutaredoxin (thioltransferase)
GTDC1 glycosyltransferase-like domain containing 1
HDLBP high density lipoprotein binding protein
HIPK2 homeodomain interacting protein kinase 2
HIST1H2AM histone cluster 1, H2am
IGHM immunoglobulin heavy constant mu
IPO5 importin 5
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KLHL22 kelch-like family member 22
KRT19P2 keratin 19 pseudogene 2
LOXL3 lysyl oxidase-like 3
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAPK7 mitogen-activated protein kinase 7
MAPK8 mitogen-activated protein kinase 8
MAPT microtubule-associated protein tau
MAST3 microtubule associated serine/threonine kinase 3
MCOLN1 mucolipin 1
MED12 mediator complex subunit 12
MED28 mediator complex subunit 28
METTL7A methyltransferase like 7A
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MTM1 myotubularin 1
MTMR3 myotubularin related protein 3
MUSK muscle, skeletal, receptor tyrosine kinase
MYO10 myosin X
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NACA2 nascent polypeptide-associated complex alpha subunit 2
NECAB2 N-terminal EF-hand calcium binding protein 2
NFX1 nuclear transcription factor, X-box binding 1
NUMA1 nuclear mitotic apparatus protein 1
PDAP1 PDGFA associated protein 1
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLCG1 phospholipase C, gamma 1
PLCH1 phospholipase C, eta 1
PMEL premelanosome protein
PTPN2 protein tyrosine phosphatase, non-receptor type 2
RARA retinoic acid receptor, alpha
RGS2 regulator of G-protein signaling 2
RPGR retinitis pigmentosa GTPase regulator
RRAGB Ras-related GTP binding B
S100A11 S100 calcium binding protein A11
SAMD9 sterile alpha motif domain containing 9
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SFTPB surfactant protein B
SIM2 single-minded family bHLH transcription factor 2
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLK STE20-like kinase
TAOK1 TAO kinase 1
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNK2 tyrosine kinase, non-receptor, 2
TOP3A topoisomerase (DNA) III alpha
TTLL1 tubulin tyrosine ligase-like family member 1
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
WFDC2 WAP four-disulfide core domain 2
ZBTB39 zinc finger and BTB domain containing 39
ZKSCAN5 zinc finger with KRAB and SCAN domains 5
ZNF202 zinc finger protein 202
ZNF783 zinc finger family member 783
ZSCAN32 zinc finger and SCAN domain containing 32

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ACADSB acyl-CoA dehydrogenase, short/branched chain
AKAP12 A kinase (PRKA) anchor protein 12
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
APOD apolipoprotein D
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATAD5 ATPase family, AAA domain containing 5
AXIN1 axin 1
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BCL9 B-cell CLL/lymphoma 9
BCORL1 BCL6 corepressor-like 1
BHLHB9 basic helix-loop-helix domain containing, class B, 9
BRAF B-Raf proto-oncogene, serine/threonine kinase
C17ORF80 chromosome 17 open reading frame 80
C22ORF29 chromosome 22 open reading frame 29
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
CLSPN claspin
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CSTA cystatin A (stefin A)
CTSV cathepsin V
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DCAF13 DDB1 and CUL4 associated factor 13
DCAF17 DDB1 and CUL4 associated factor 17
DCLRE1A DNA cross-link repair 1A
DVL1 dishevelled segment polarity protein 1
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
FAM160B2 family with sequence similarity 160, member B2
FAM65A family with sequence similarity 65, member A
FCHSD2 FCH and double SH3 domains 2
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GPATCH2L G patch domain containing 2-like
GPX2 glutathione peroxidase 2
HIST1H2AJ histone cluster 1, H2aj
IFT140 intraflagellar transport 140
IFT22 intraflagellar transport 22
INPPL1 inositol polyphosphate phosphatase-like 1
JMJD4 jumonji domain containing 4
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KLF2 Kruppel-like factor 2
LAMA3 laminin, alpha 3
LOC257152 uncharacterized LOC257152
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LRP5 low density lipoprotein receptor-related protein 5
LZTR1 leucine-zipper-like transcription regulator 1
MAGEF1 melanoma antigen family F1
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MTA2 metastasis associated 1 family, member 2
MYBBP1A MYB binding protein (P160) 1a
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NCAM2 neural cell adhesion molecule 2
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NEK11 NIMA-related kinase 11
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PGP phosphoglycolate phosphatase
PHF21A PHD finger protein 21A
PKN1 protein kinase N1
PLD2 phospholipase D2
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
POMT1 protein-O-mannosyltransferase 1
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RCOR3 REST corepressor 3
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNF31 ring finger protein 31
RPL13P5 ribosomal protein L13 pseudogene 5
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RWDD3 RWD domain containing 3
SCN1B sodium channel, voltage gated, type I beta subunit
SIDT1 SID1 transmembrane family, member 1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SP1 Sp1 transcription factor
SP140L SP140 nuclear body protein-like
SPHK1 sphingosine kinase 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STK25 serine/threonine kinase 25
TBC1D17 TBC1 domain family, member 17
TEAD3 TEA domain family member 3
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
URM1 ubiquitin related modifier 1
WDR62 WD repeat domain 62
WDR76 WD repeat domain 76
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZDHHC18 zinc finger, DHHC-type containing 18
ZNF276 zinc finger protein 276
ZNF282 zinc finger protein 282
ZNF324 zinc finger protein 324
ZNF350 zinc finger protein 350
ZNF552 zinc finger protein 552
ZNF75D zinc finger protein 75D