genistein-4459 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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199 genes differentially expressed following the genistein-4459 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ACAN aggrecan
ADGRB1 adhesion G protein-coupled receptor B1
ADGRL2 adhesion G protein-coupled receptor L2
ADORA3 adenosine A3 receptor
AHSP alpha hemoglobin stabilizing protein
AKR1C4 aldo-keto reductase family 1, member C4
ATHL1 ATH1, acid trehalase-like 1 (yeast)
BCAM basal cell adhesion molecule (Lutheran blood group)
BGN biglycan
BST1 bone marrow stromal cell antigen 1
C7ORF43 chromosome 7 open reading frame 43
CCNT1 cyclin T1
CD22 CD22 molecule
CD248 CD248 molecule, endosialin
CD6 CD6 molecule
CDHR2 cadherin-related family member 2
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CHAT choline O-acetyltransferase
CLCN7 chloride channel, voltage-sensitive 7
CNPY4 canopy FGF signaling regulator 4
CST2 cystatin SA
CWH43 cell wall biogenesis 43 C-terminal homolog (S. cerevisiae)
DGKE diacylglycerol kinase, epsilon 64kDa
DST dystonin
DUSP2 dual specificity phosphatase 2
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ERAP1 endoplasmic reticulum aminopeptidase 1
FAS Fas cell surface death receptor
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FOXG1 forkhead box G1
FUBP1 far upstream element (FUSE) binding protein 1
HBB hemoglobin, beta
HFE hemochromatosis
HHIPL2 HHIP-like 2
IFI27 interferon, alpha-inducible protein 27
IL11 interleukin 11
IRAK3 interleukin-1 receptor-associated kinase 3
IRF4 interferon regulatory factor 4
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGA7 integrin, alpha 7
KANSL3 KAT8 regulatory NSL complex subunit 3
KCNIP1 Kv channel interacting protein 1
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KIF25-AS1 KIF25 antisense RNA 1
KIRREL kin of IRRE like (Drosophila)
KLHL4 kelch-like family member 4
LAMA4 laminin, alpha 4
LAT2 linker for activation of T cells family, member 2
LATS1 large tumor suppressor kinase 1
LDAH lipid droplet associated hydrolase
LMO2 LIM domain only 2 (rhombotin-like 1)
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAPK11 mitogen-activated protein kinase 11
MED25 mediator complex subunit 25
MIP major intrinsic protein of lens fiber
NELL2 NEL-like 2 (chicken)
NRF1 nuclear respiratory factor 1
PBX2 pre-B-cell leukemia homeobox 2
PDE2A phosphodiesterase 2A, cGMP-stimulated
PDE4B phosphodiesterase 4B, cAMP-specific
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PGK2 phosphoglycerate kinase 2
PLVAP plasmalemma vesicle associated protein
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PTCRA pre T-cell antigen receptor alpha
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RBFA ribosome binding factor A (putative)
RGS3 regulator of G-protein signaling 3
RIMS2 regulating synaptic membrane exocytosis 2
S100A12 S100 calcium binding protein A12
SCN1A sodium channel, voltage gated, type I alpha subunit
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SFTPB surfactant protein B
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SNX13 sorting nexin 13
SPTBN1 spectrin, beta, non-erythrocytic 1
SPTBN5 spectrin, beta, non-erythrocytic 5
STS steroid sulfatase (microsomal), isozyme S
SULF1 sulfatase 1
TAC3 tachykinin 3
TAF7L TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa
TAT tyrosine aminotransferase
TBC1D2B TBC1 domain family, member 2B
TCP11L1 t-complex 11, testis-specific-like 1
TDRD1 tudor domain containing 1
TGM4 transglutaminase 4
THRA thyroid hormone receptor, alpha
TM4SF4 transmembrane 4 L six family member 4
TNFRSF4 tumor necrosis factor receptor superfamily, member 4
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
WIZ widely interspaced zinc finger motifs
XYLB xylulokinase homolog (H. influenzae)
ZNF384 zinc finger protein 384
ZNF516 zinc finger protein 516

decreased expression

Symbol Name
ADGRB2 adhesion G protein-coupled receptor B2
AK5 adenylate kinase 5
ALG12 ALG12, alpha-1,6-mannosyltransferase
ARL15 ADP-ribosylation factor-like 15
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATAT1 alpha tubulin acetyltransferase 1
BMPR1B bone morphogenetic protein receptor, type IB
CD79B CD79b molecule, immunoglobulin-associated beta
CD82 CD82 molecule
CDK6 cyclin-dependent kinase 6
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CENPJ centromere protein J
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CNGA1 cyclic nucleotide gated channel alpha 1
COL9A3 collagen, type IX, alpha 3
COLGALT2 collagen beta(1-O)galactosyltransferase 2
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DBF4B DBF4 zinc finger B
DEPDC5 DEP domain containing 5
DNAH17 dynein, axonemal, heavy chain 17
DNM3 dynamin 3
EDIL3 EGF-like repeats and discoidin I-like domains 3
EFNA3 ephrin-A3
EGFL7 EGF-like-domain, multiple 7
EML4 echinoderm microtubule associated protein like 4
EPHA4 EPH receptor A4
FAM102A family with sequence similarity 102, member A
FAM131B family with sequence similarity 131, member B
FBXO2 F-box protein 2
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FKRP fukutin related protein
FZD8 frizzled class receptor 8
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPR176 G protein-coupled receptor 176
GTF2A1 general transcription factor IIA, 1, 19/37kDa
H1F0 H1 histone family, member 0
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HHLA1 HERV-H LTR-associating 1
HLX H2.0-like homeobox
HOXC5 homeobox C5
HYAL3 hyaluronoglucosaminidase 3
IL12A interleukin 12A
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
INPP5J inositol polyphosphate-5-phosphatase J
IPO8 importin 8
ITPKB inositol-trisphosphate 3-kinase B
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KDM5C lysine (K)-specific demethylase 5C
KLHL29 kelch-like family member 29
KLK7 kallikrein-related peptidase 7
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MCOLN3 mucolipin 3
MDFI MyoD family inhibitor
MED9 mediator complex subunit 9
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
MMP2 matrix metallopeptidase 2
NKX3-2 NK3 homeobox 2
NRTN neurturin
OLFML2B olfactomedin-like 2B
OSMR oncostatin M receptor
PADI2 peptidyl arginine deiminase, type II
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PCDHGB5 protocadherin gamma subfamily B, 5
PCOLCE procollagen C-endopeptidase enhancer
PHEX phosphate regulating endopeptidase homolog, X-linked
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PLA1A phospholipase A1 member A
POLL polymerase (DNA directed), lambda
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
PRKG2 protein kinase, cGMP-dependent, type II
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
RAB40AL RAB40A, member RAS oncogene family-like
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RNF39 ring finger protein 39
SCGB2A2 secretoglobin, family 2A, member 2
SKIL SKI-like proto-oncogene
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SNRPN small nuclear ribonucleoprotein polypeptide N
SP1 Sp1 transcription factor
STEAP4 STEAP family member 4
THRAP3 thyroid hormone receptor associated protein 3
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TUBA4B tubulin, alpha 4b
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
WDR25 WD repeat domain 25
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZC3H12A zinc finger CCCH-type containing 12A
ZNF205 zinc finger protein 205
ZNF41 zinc finger protein 41
ZNF639 zinc finger protein 639
ZNF76 zinc finger protein 76
ZSCAN2 zinc finger and SCAN domain containing 2