gastrointestinal tract polyps Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description abnormal tissue masses that protrude into the lumen of the gastrointestinal tract and are tethered to the wall of the gastrointestinal tract (Mammalian Phenotype Ontology, MP_0010352)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0010352
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Genes

11 gene mutations causing the gastrointestinal tract polyps phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AHR aryl hydrocarbon receptor
APC adenomatous polyposis coli
CDX2 caudal type homeobox 2
MCM2 minichromosome maintenance complex component 2
MSH2 mutS homolog 2
PPARD peroxisome proliferator-activated receptor delta
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PTEN phosphatase and tensin homolog
SMAD4 SMAD family member 4
STK11 serine/threonine kinase 11
TP53 tumor protein p53