gastrointestinal system cancer Gene Set

Dataset DISEASES Experimental Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description An organ system cancer located_in gastrointestinal tract that is manifested in organs of the gastrointestinal system. (Human Disease Ontology, DOID_3119)
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Genes

45 genes associated with the disease gastrointestinal system cancer in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 1.79724
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit 1.70756
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 1.53808
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 1.52581
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 1.44921
RUNX1 runt-related transcription factor 1 1.44218
ACAD10 acyl-CoA dehydrogenase family, member 10 1.40682
PDE4D phosphodiesterase 4D, cAMP-specific 1.32252
KIF1B kinesin family member 1B 1.27521
RPL6 ribosomal protein L6 1.07383
MICA MHC class I polypeptide-related sequence A 0.923046
UNC5CL unc-5 homolog C (C. elegans)-like 0.830123
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A 0.817078
GRIK1 glutamate receptor, ionotropic, kainate 1 0.661797
PLCE1 phospholipase C, epsilon 1 0.602429
ZBTB20 zinc finger and BTB domain containing 20 0.602429
CSNK1A1 casein kinase 1, alpha 1 0.561725
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 0.552621
CHEK2 checkpoint kinase 2 0.52461
DCC DCC netrin 1 receptor 0.4215
SEMA5B sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B 0.403461
GLB1 galactosidase, beta 1 0.368757
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2 0.345945
KIF16B kinesin family member 16B 0.327313
MUC1 mucin 1, cell surface associated 0.327313
TAC1 tachykinin, precursor 1 0.311576
CNTN4 contactin 4 0.264872
ITGA1 integrin, alpha 1 0.197766
CFB complement factor B 0.197766
CAAP1 caspase activity and apoptosis inhibitor 1 0.197766
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.197766
EFCAB11 EF-hand calcium binding domain 11 0.126165
FGF12 fibroblast growth factor 12 0.064973
KIAA0825 KIAA0825 0.064973
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 0.052255
HLA-C major histocompatibility complex, class I, C 0.009941
HLA-A major histocompatibility complex, class I, A 0.008048
HLA-J major histocompatibility complex, class I, J (pseudogene) 0.00317
TNFRSF19 tumor necrosis factor receptor superfamily, member 19 0.002018
MECOM MDS1 and EVI1 complex locus 0.001614
IER3 immediate early response 3 0.001467
ITGA9 integrin, alpha 9 0.001215
BLACE B-cell acute lymphoblastic leukemia expressed 8.05E-4
WLS wntless Wnt ligand secretion mediator 6.64E-4
HS3ST4 heparan sulfate (glucosamine) 3-O-sulfotransferase 4 4.99E-4