gastrointestinal endocrine cell Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description Cells found throughout the lining of the gastrointestinal tract that contain regulatory peptide hormones and/or biogenic amines. The substances are located in secretory granules and act in an endocrine or paracrine manner. Some of these substances are also found in neurons in the gut. There are at least 15 different types of endocrine cells of the gut. Some take up amine precursors and have been called APUD CELLS. However, most endocrine cells of the gut apparently have endodermal rather than neuroectodermal origin, so the relationship with APUD cells is not clear. (BRENDA Tissue and Enzyme Source Ontology, BTO_0001895)
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Genes

30 proteins co-occuring with the tissue gastrointestinal endocrine cell in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
GAST gastrin 1.75024
SST somatostatin 1.4394
MLN motilin 1.33184
PPY pancreatic polypeptide 1.31965
CCK cholecystokinin 1.28861
PYY peptide YY 1.25592
GCG glucagon 1.23004
GHRL ghrelin/obestatin prepropeptide 0.94867
PTPRS protein tyrosine phosphatase, receptor type, S 0.904127
NTS neurotensin 0.88671
CHGA chromogranin A 0.873594
RTN1 reticulon 1 0.873172
NEUROG3 neurogenin 3 0.844545
HAP1 huntingtin-associated protein 1 0.807716
GIP gastric inhibitory polypeptide 0.795624
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha 0.78522
DDN dendrin 0.751645
IAPP islet amyloid polypeptide 0.737206
SHPK sedoheptulokinase 0.719934
GRP gastrin-releasing peptide 0.658678
KDM1A lysine (K)-specific demethylase 1A 0.57082
PAX4 paired box 4 0.537812
TAC1 tachykinin, precursor 1 0.444884
INS insulin 0.390799
PTS 6-pyruvoyltetrahydropterin synthase 0.357058
RTN4 reticulon 4 0.32205
RREB1 ras responsive element binding protein 1 0.304279
NEUROD1 neuronal differentiation 1 0.236627
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 0.226411
HNF1A HNF1 homeobox A 0.221989