ganciclovir-3368 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the ganciclovir-3368 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM8 ADAM metallopeptidase domain 8
ADGRE1 adhesion G protein-coupled receptor E1
AHSG alpha-2-HS-glycoprotein
AKAP8L A kinase (PRKA) anchor protein 8-like
ASIC2 acid sensing (proton gated) ion channel 2
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BCL2L2 BCL2-like 2
C19ORF66 chromosome 19 open reading frame 66
CD52 CD52 molecule
CD6 CD6 molecule
CD8A CD8a molecule
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CNTNAP3B contactin associated protein-like 3B
COL6A1 collagen, type VI, alpha 1
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DAPK3 death-associated protein kinase 3
DOPEY2 dopey family member 2
EGFR epidermal growth factor receptor
ERAP1 endoplasmic reticulum aminopeptidase 1
ERP44 endoplasmic reticulum protein 44
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FLRT2 fibronectin leucine rich transmembrane protein 2
FRMD4A FERM domain containing 4A
FZD5 frizzled class receptor 5
GAS2L1 growth arrest-specific 2 like 1
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GGT1 gamma-glutamyltransferase 1
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GPER1 G protein-coupled estrogen receptor 1
GSTP1 glutathione S-transferase pi 1
GUCA1B guanylate cyclase activator 1B (retina)
HIST1H3F histone cluster 1, H3f
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HLF hepatic leukemia factor
HOXB6 homeobox B6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGKV1D-13 immunoglobulin kappa variable 1D-13
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITPK1 inositol-tetrakisphosphate 1-kinase
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KDM4B lysine (K)-specific demethylase 4B
KIF21B kinesin family member 21B
KRT37 keratin 37, type I
LTBP2 latent transforming growth factor beta binding protein 2
MAPK7 mitogen-activated protein kinase 7
MIER2 mesoderm induction early response 1, family member 2
MMP11 matrix metallopeptidase 11
MRC2 mannose receptor, C type 2
MSC musculin
MSR1 macrophage scavenger receptor 1
MST1 macrophage stimulating 1
MUC2 mucin 2, oligomeric mucus/gel-forming
MVB12B multivesicular body subunit 12B
MYCNOS MYCN opposite strand
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle
NCLN nicalin
NDN necdin, melanoma antigen (MAGE) family member
NDRG2 NDRG family member 2
NID1 nidogen 1
NNAT neuronatin
NOV nephroblastoma overexpressed
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
OR10H1 olfactory receptor, family 10, subfamily H, member 1
PADI3 peptidyl arginine deiminase, type III
PCSK6 proprotein convertase subtilisin/kexin type 6
PHC3 polyhomeotic homolog 3 (Drosophila)
PLCL2 phospholipase C-like 2
PLXNA2 plexin A2
PRM1 protamine 1
PRR34 proline rich 34
PTK2B protein tyrosine kinase 2 beta
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RUNDC3A RUN domain containing 3A
SAMD9 sterile alpha motif domain containing 9
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SOAT2 sterol O-acyltransferase 2
SRRT serrate, RNA effector molecule
STS steroid sulfatase (microsomal), isozyme S
STXBP5L syntaxin binding protein 5-like
T T, brachyury homolog (mouse)
TAOK2 TAO kinase 2
TCF20 transcription factor 20 (AR1)
TGM2 transglutaminase 2
TM4SF1 transmembrane 4 L six family member 1
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TRBC1 T cell receptor beta constant 1
TRIM29 tripartite motif containing 29
TRIM38 tripartite motif containing 38
UBA6 ubiquitin-like modifier activating enzyme 6
ULBP1 UL16 binding protein 1

decreased expression

Symbol Name
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ACTL8 actin-like 8
ADTRP androgen-dependent TFPI-regulating protein
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ALOX15 arachidonate 15-lipoxygenase
ANXA2P3 annexin A2 pseudogene 3
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ARPIN actin-related protein 2/3 complex inhibitor
ATHL1 ATH1, acid trehalase-like 1 (yeast)
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C11ORF80 chromosome 11 open reading frame 80
C4ORF29 chromosome 4 open reading frame 29
CBR4 carbonyl reductase 4
CTSF cathepsin F
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DMC1 DNA meiotic recombinase 1
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22
DPY19L1P1 DPY19L1 pseudogene 1
DYSF dysferlin
EDAR ectodysplasin A receptor
EGR3 early growth response 3
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ELOVL4 ELOVL fatty acid elongase 4
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ERN1 endoplasmic reticulum to nucleus signaling 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM131A family with sequence similarity 131, member A
FGD1 FYVE, RhoGEF and PH domain containing 1
FKBP14 FK506 binding protein 14, 22 kDa
FKBPL FK506 binding protein like
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLB1L galactosidase, beta 1-like
GMEB1 glucocorticoid modulatory element binding protein 1
GMPR guanosine monophosphate reductase
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H1E histone cluster 1, H1e
HIST1H4D histone cluster 1, H4d
HOXC5 homeobox C5
IFNAR1 interferon (alpha, beta and omega) receptor 1
KIFC1 kinesin family member C1
LRP5L low density lipoprotein receptor-related protein 5-like
LRRC37A3 leucine rich repeat containing 37, member A3
LYPLA2P1 lysophospholipase II pseudogene 1
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K8 mitogen-activated protein kinase kinase kinase 8
METTL16 methyltransferase like 16
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
NME6 NME/NM23 nucleoside diphosphate kinase 6
NUBPL nucleotide binding protein-like
ONECUT2 one cut homeobox 2
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OSMR oncostatin M receptor
PDIA3 protein disulfide isomerase family A, member 3
PHEX phosphate regulating endopeptidase homolog, X-linked
PHF14 PHD finger protein 14
PIGH phosphatidylinositol glycan anchor biosynthesis, class H
PLA2G10 phospholipase A2, group X
PLA2G3 phospholipase A2, group III
PLCD1 phospholipase C, delta 1
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
POLH polymerase (DNA directed), eta
POM121 POM121 transmembrane nucleoporin
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PSPH phosphoserine phosphatase
RAB3A RAB3A, member RAS oncogene family
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RHBG Rh family, B glycoprotein (gene/pseudogene)
RPAP1 RNA polymerase II associated protein 1
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SECTM1 secreted and transmembrane 1
SERGEF secretion regulating guanine nucleotide exchange factor
SIX1 SIX homeobox 1
SLC12A8 solute carrier family 12, member 8
SLC46A3 solute carrier family 46, member 3
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SOWAHC sosondowah ankyrin repeat domain family member C
SPEG SPEG complex locus
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
STARD5 StAR-related lipid transfer (START) domain containing 5
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TARP TCR gamma alternate reading frame protein
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TEP1 telomerase-associated protein 1
TEX40 testis expressed 40
TMEM242 transmembrane protein 242
TRIM16 tripartite motif containing 16
UPK2 uroplakin 2
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZFHX4 zinc finger homeobox 4
ZFP30 ZFP30 zinc finger protein
ZNF430 zinc finger protein 430
ZNF652 zinc finger protein 652
ZNF701 zinc finger protein 701
ZNF721 zinc finger protein 721