ganciclovir-3030 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the ganciclovir-3030 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
ADCK2 aarF domain containing kinase 2
ADCY10 adenylate cyclase 10 (soluble)
ADIRF adipogenesis regulatory factor
ADORA1 adenosine A1 receptor
ADRBK1 adrenergic, beta, receptor kinase 1
APOA4 apolipoprotein A-IV
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
AQP1 aquaporin 1 (Colton blood group)
AQP4 aquaporin 4
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARHGAP33 Rho GTPase activating protein 33
ARHGAP35 Rho GTPase activating protein 35
AURKA aurora kinase A
C2ORF27A chromosome 2 open reading frame 27A
C9ORF116 chromosome 9 open reading frame 116
CAMK4 calcium/calmodulin-dependent protein kinase IV
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CCDC85B coiled-coil domain containing 85B
CD163 CD163 molecule
CDHR5 cadherin-related family member 5
CLCA1 chloride channel accessory 1
COL10A1 collagen, type X, alpha 1
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
COMT catechol-O-methyltransferase
CRABP2 cellular retinoic acid binding protein 2
DCX doublecortin
DDO D-aspartate oxidase
DGKQ diacylglycerol kinase, theta 110kDa
DLK2 delta-like 2 homolog (Drosophila)
DUSP4 dual specificity phosphatase 4
EFNA3 ephrin-A3
ENDOD1 endonuclease domain containing 1
EPHA5 EPH receptor A5
EPX eosinophil peroxidase
EYA3 EYA transcriptional coactivator and phosphatase 3
FBLN1 fibulin 1
FBXO40 F-box protein 40
FERMT1 fermitin family member 1
FRMD4A FERM domain containing 4A
FZD10 frizzled class receptor 10
G0S2 G0/G1 switch 2
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GLRA3 glycine receptor, alpha 3
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GRM1 glutamate receptor, metabotropic 1
GSG1 germ cell associated 1
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HFE hemochromatosis
HOXB7 homeobox B7
HRASLS2 HRAS-like suppressor 2
HSPB8 heat shock 22kDa protein 8
HYI hydroxypyruvate isomerase (putative)
IL23A interleukin 23, alpha subunit p19
IL3RA interleukin 3 receptor, alpha (low affinity)
ITGB4 integrin, beta 4
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KCNK10 potassium channel, two pore domain subfamily K, member 10
LAMB2 laminin, beta 2 (laminin S)
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LOC730101 uncharacterized LOC730101
LOX lysyl oxidase
MAN1A2 mannosidase, alpha, class 1A, member 2
MPPE1 metallophosphoesterase 1
MSH4 mutS homolog 4
NOP16 NOP16 nucleolar protein
NR2F2 nuclear receptor subfamily 2, group F, member 2
NRP2 neuropilin 2
NXPH3 neurexophilin 3
OLIG2 oligodendrocyte lineage transcription factor 2
PDLIM4 PDZ and LIM domain 4
PLCG1 phospholipase C, gamma 1
PLP1 proteolipid protein 1
PLXNB2 plexin B2
PPARA peroxisome proliferator-activated receptor alpha
PPP1R37 protein phosphatase 1, regulatory subunit 37
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RARB retinoic acid receptor, beta
REPS2 RALBP1 associated Eps domain containing 2
RNF17 ring finger protein 17
SAGE1 sarcoma antigen 1
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SIGLEC7 sialic acid binding Ig-like lectin 7
SLC13A1 solute carrier family 13 (sodium/sulfate symporter), member 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TACSTD2 tumor-associated calcium signal transducer 2
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
TBL1Y transducin (beta)-like 1, Y-linked
TIMELESS timeless circadian clock
TNIK TRAF2 and NCK interacting kinase
TP53I11 tumor protein p53 inducible protein 11
UNC5B unc-5 homolog B (C. elegans)
ZNF639 zinc finger protein 639
ZNF646 zinc finger protein 646

decreased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ARHGAP10 Rho GTPase activating protein 10
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BBS7 Bardet-Biedl syndrome 7
BTF3P11 basic transcription factor 3 pseudogene 11
C1ORF159 chromosome 1 open reading frame 159
C1ORF56 chromosome 1 open reading frame 56
C5 complement component 5
C9ORF3 chromosome 9 open reading frame 3
C9ORF9 chromosome 9 open reading frame 9
CDR2L cerebellar degeneration-related protein 2-like
CENPO centromere protein O
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CROT carnitine O-octanoyltransferase
CRYBG3 beta-gamma crystallin domain containing 3
DCAF17 DDB1 and CUL4 associated factor 17
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
EDAR ectodysplasin A receptor
ELAVL3 ELAV like neuron-specific RNA binding protein 3
EPHB6 EPH receptor B6
ERCC4 excision repair cross-complementation group 4
ERCC6 excision repair cross-complementation group 6
FAM102A family with sequence similarity 102, member A
FBXL7 F-box and leucine-rich repeat protein 7
FER fer (fps/fes related) tyrosine kinase
FGF23 fibroblast growth factor 23
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GCH1 GTP cyclohydrolase 1
GIF gastric intrinsic factor (vitamin B synthesis)
GLRA1 glycine receptor, alpha 1
GPC3 glypican 3
GPR3 G protein-coupled receptor 3
HIST1H2AJ histone cluster 1, H2aj
HIST1H2AM histone cluster 1, H2am
HIST1H3G histone cluster 1, H3g
HOXC8 homeobox C8
HSPB6 heat shock protein, alpha-crystallin-related, B6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
KIF23 kinesin family member 23
KIF3B kinesin family member 3B
KLHL36 kelch-like family member 36
KRT31 keratin 31, type I
LIG4 ligase IV, DNA, ATP-dependent
LIME1 Lck interacting transmembrane adaptor 1
LINC00597 long intergenic non-protein coding RNA 597
LOXL3 lysyl oxidase-like 3
LYPLA2P1 lysophospholipase II pseudogene 1
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MCPH1 microcephalin 1
MKRN3 makorin ring finger protein 3
MPZ myelin protein zero
MTSS1L metastasis suppressor 1-like
NCS1 neuronal calcium sensor 1
NEK11 NIMA-related kinase 11
NFE2L3 nuclear factor, erythroid 2-like 3
NIPAL2 NIPA-like domain containing 2
NME8 NME/NM23 family member 8
NT5DC3 5'-nucleotidase domain containing 3
NXPE3 neurexophilin and PC-esterase domain family, member 3
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PELP1 proline, glutamate and leucine rich protein 1
PGP phosphoglycolate phosphatase
PLAT plasminogen activator, tissue
PMP22 peripheral myelin protein 22
PRB3 proline-rich protein BstNI subfamily 3
PROCR protein C receptor, endothelial
PRSS53 protease, serine, 53
RAB17 RAB17, member RAS oncogene family
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RIN1 Ras and Rab interactor 1
RIN2 Ras and Rab interactor 2
RPRD2 regulation of nuclear pre-mRNA domain containing 2
SALL2 spalt-like transcription factor 2
SGMS1 sphingomyelin synthase 1
SLC17A2 solute carrier family 17, member 2
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLITRK5 SLIT and NTRK-like family, member 5
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SURF2 surfeit 2
SYTL2 synaptotagmin-like 2
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TBX19 T-box 19
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TLR6 toll-like receptor 6
TRAF2 TNF receptor-associated factor 2
TRPC5 transient receptor potential cation channel, subfamily C, member 5
ZBED1 zinc finger, BED-type containing 1
ZNF484 zinc finger protein 484
ZNF493 zinc finger protein 493
ZNF76 zinc finger protein 76
ZNF862 zinc finger protein 862
ZXDB zinc finger, X-linked, duplicated B