gallbladder cancer Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A biliary tract cancer that is located_in the gallbladder. (Human Disease Ontology, DOID_3121)
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Genes

276 genes co-occuring with the disease gallbladder cancer in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
ZNF135 zinc finger protein 135 1.63769
PDPN podoplanin 1.53789
TP53 tumor protein p53 1.51501
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 1.44342
KRAS Kirsten rat sarcoma viral oncogene homolog 1.42454
HRAS Harvey rat sarcoma viral oncogene homolog 1.3952
LAPTM4B lysosomal protein transmembrane 4 beta 1.19014
BTC betacellulin 0.99697
PCNA proliferating cell nuclear antigen 0.957868
MUC1 mucin 1, cell surface associated 0.952021
NMT1 N-myristoyltransferase 1 0.936629
CLEC3A C-type lectin domain family 3, member A 0.934141
CLEC2B C-type lectin domain family 2, member B 0.928759
CLEC10A C-type lectin domain family 10, member A 0.90321
ERBB2 erb-b2 receptor tyrosine kinase 2 0.901156
CDKN2A cyclin-dependent kinase inhibitor 2A 0.864274
MUC2 mucin 2, oligomeric mucus/gel-forming 0.859362
MUC4 mucin 4, cell surface associated 0.848716
SCAMP1 secretory carrier membrane protein 1 0.835607
FHIT fragile histidine triad 0.819206
NEK7 NIMA-related kinase 7 0.819206
HIST1H1D histone cluster 1, H1d 0.814693
NLK nemo-like kinase 0.811821
TMEM11 transmembrane protein 11 0.808539
INF2 inverted formin, FH2 and WH2 domain containing 0.804026
PSCA prostate stem cell antigen 0.776977
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.776977
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 0.770027
GBAS glioblastoma amplified sequence 0.761454
EBAG9 estrogen receptor binding site associated, antigen, 9 0.759008
S100A9 S100 calcium binding protein A9 0.75412
AFP alpha-fetoprotein 0.75005
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 0.740705
MLH1 mutL homolog 1 0.735433
KRT7 keratin 7, type II 0.732596
LZIC leucine zipper and CTNNBIP1 domain containing 0.728143
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.711183
CCKAR cholecystokinin A receptor 0.700722
EGFR epidermal growth factor receptor 0.65288
C19ORF48 chromosome 19 open reading frame 48 0.652484
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.650508
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 0.637495
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.631598
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.623751
PDIA2 protein disulfide isomerase family A, member 2 0.593285
ALPPL2 alkaline phosphatase, placental-like 2 0.589001
ALPP alkaline phosphatase, placental 0.588222
ALPL alkaline phosphatase, liver/bone/kidney 0.587833
MMP2 matrix metallopeptidase 2 0.586665
BAX BCL2-associated X protein 0.583163
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8 0.578494
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 0.57655
APP amyloid beta (A4) precursor protein 0.569552
CD44 CD44 molecule (Indian blood group) 0.563335
CHD5 chromodomain helicase DNA binding protein 5 0.545868
MTDH metadherin 0.541217
CCND1 cyclin D1 0.541217
PLCE1 phospholipase C, epsilon 1 0.526518
HDGF hepatoma-derived growth factor 0.522273
EPHA7 EPH receptor A7 0.517649
OGG1 8-oxoguanine DNA glycosylase 0.517265
VEGFC vascular endothelial growth factor C 0.510344
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.505356
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 0.503824
ANXA3 annexin A3 0.501144
TIMP2 TIMP metallopeptidase inhibitor 2 0.498849
NEK8 NIMA-related kinase 8 0.496939
CCT2 chaperonin containing TCP1, subunit 2 (beta) 0.492359
WDR1 WD repeat domain 1 0.487407
CHGA chromogranin A 0.479427
FCGBP Fc fragment of IgG binding protein 0.468063
KRT20 keratin 20, type I 0.468063
CD82 CD82 molecule 0.450324
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 0.447687
S100A10 S100 calcium binding protein A10 0.436402
BIRC5 baculoviral IAP repeat containing 5 0.420641
STOML2 stomatin (EPB72)-like 2 0.420266
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.416896
MUC6 mucin 6, oligomeric mucus/gel-forming 0.415398
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase 0.41465
SST somatostatin 0.410909
PCBP1 poly(rC) binding protein 1 0.410535
INADL InaD-like (Drosophila) 0.407172
HHAT hedgehog acyltransferase 0.406798
CCK cholecystokinin 0.406051
ACVR1C activin A receptor, type IC 0.398962
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) 0.395235
FBXO8 F-box protein 8 0.393001
C6ORF25 chromosome 6 open reading frame 25 0.390025
GSTM1 glutathione S-transferase mu 1 0.385565
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 0.377402
MSH2 mutS homolog 2 0.375179
FOXL1 forkhead box L1 0.374068
DPYD dihydropyrimidine dehydrogenase 0.369628
TFPI2 tissue factor pathway inhibitor 2 0.368149
ANXA5 annexin A5 0.364824
CTSZ cathepsin Z 0.362978
MMP9 matrix metallopeptidase 9 0.360764
MKI67 marker of proliferation Ki-67 0.358183
ENO2 enolase 2 (gamma, neuronal) 0.344207
PLK1 polo-like kinase 1 0.339806
SRR serine racemase 0.333218
SSTR1 somatostatin receptor 1 0.331756
HPSE heparanase 0.331391
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.330295
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.329565
PRKACB protein kinase, cAMP-dependent, catalytic, beta 0.326281
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.32373
FGFBP1 fibroblast growth factor binding protein 1 0.322273
SYP synaptophysin 0.318999
GDI2 GDP dissociation inhibitor 2 0.317182
SDC1 syndecan 1 0.312464
FFAR2 free fatty acid receptor 2 0.31029
ERP29 endoplasmic reticulum protein 29 0.30848
WARS tryptophanyl-tRNA synthetase 0.307033
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 0.30631
PPY pancreatic polypeptide 0.304864
TMPRSS13 transmembrane protease, serine 13 0.300533
MSI1 musashi RNA-binding protein 1 0.300533
TSC2 tuberous sclerosis 2 0.299452
REG4 regenerating islet-derived family, member 4 0.299092
CD34 CD34 molecule 0.299092
TRO trophinin 0.289744
CKS2 CDC28 protein kinase regulatory subunit 2 0.287952
PITX1 paired-like homeodomain 1 0.286877
NR1H2 nuclear receptor subfamily 1, group H, member 2 0.28616
FOXM1 forkhead box M1 0.285086
PEBP1 phosphatidylethanolamine binding protein 1 0.28294
PLAGL2 pleiomorphic adenoma gene-like 2 0.282582
APOB apolipoprotein B 0.28151
EPCAM epithelial cell adhesion molecule 0.28151
SCN10A sodium channel, voltage gated, type X alpha subunit 0.279724
PROM1 prominin 1 0.279367
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 0.275089
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa 0.269753
LIN9 lin-9 DREAM MuvB core complex component 0.260891
ALB albumin 0.260184
CDH13 cadherin 13 0.259124
GGT2 gamma-glutamyltransferase 2 0.257711
ANKRD11 ankyrin repeat domain 11 0.254888
GLI1 GLI family zinc finger 1 0.254888
FSCN3 fascin actin-bundling protein 3, testicular 0.254536
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.254536
ASMT acetylserotonin O-methyltransferase 0.246799
WISP2 WNT1 inducible signaling pathway protein 2 0.245396
VEGFA vascular endothelial growth factor A 0.244696
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.242945
GIPC1 GIPC PDZ domain containing family, member 1 0.241546
ESPN espin 0.240847
BCL10 B-cell CLL/lymphoma 10 0.238403
ELAVL1 ELAV like RNA binding protein 1 0.235616
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 0.235616
TMPRSS4 transmembrane protease, serine 4 0.234225
CD24 CD24 molecule 0.231102
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 0.231102
ANTXR1 anthrax toxin receptor 1 0.231102
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4 0.230063
FSCN2 fascin actin-bundling protein 2, retinal 0.230063
ADGRE5 adhesion G protein-coupled receptor E5 0.22937
GPR17 G protein-coupled receptor 17 0.227988
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B) 0.224196
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.220766
ZFX zinc finger protein, X-linked 0.219398
TIMP3 TIMP metallopeptidase inhibitor 3 0.218715
TSC1 tuberous sclerosis 1 0.217012
TERT telomerase reverse transcriptase 0.217012
ESR2 estrogen receptor 2 (ER beta) 0.215653
CDX2 caudal type homeobox 2 0.212608
DDX53 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 0.210925
CLIC1 chloride intracellular channel 1 0.208914
TYMP thymidine phosphorylase 0.205585
UHRF1 ubiquitin-like with PHD and ring finger domains 1 0.205585
MET MET proto-oncogene, receptor tyrosine kinase 0.19742
FLNA filamin A, alpha 0.196779
ODC1 ornithine decarboxylase 1 0.196139
ASXL1 additional sex combs like transcriptional regulator 1 0.19582
NKX2-1 NK2 homeobox 1 0.191719
DLC1 DLC1 Rho GTPase activating protein 0.189551
CCNB2 cyclin B2 0.188938
AANAT aralkylamine N-acetyltransferase 0.18651
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 0.182666
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.182375
TYMS thymidylate synthetase 0.178403
MACC1 metastasis associated in colon cancer 1 0.175679
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.175679
UBE2C ubiquitin-conjugating enzyme E2C 0.175411
ERCC1 excision repair cross-complementation group 1 0.174617
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.173571
GGT1 gamma-glutamyltransferase 1 0.172291
ZMYND10 zinc finger, MYND-type containing 10 0.171785
RAB1A RAB1A, member RAS oncogene family 0.170544
DAPK1 death-associated protein kinase 1 0.169571
CUTA cutA divalent cation tolerance homolog (E. coli) 0.168854
GBA glucosidase, beta, acid 0.167915
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 0.167452
RRM1 ribonucleotide reductase M1 0.165435
SMAD4 SMAD family member 4 0.165435
SSTR4 somatostatin receptor 4 0.164786
CD1C CD1c molecule 0.164786
PLAU plasminogen activator, urokinase 0.164571
PGR progesterone receptor 0.164571
CGB7 chorionic gonadotropin, beta polypeptide 7 0.163111
HSPA8 heat shock 70kDa protein 8 0.162505
CGB5 chorionic gonadotropin, beta polypeptide 5 0.162306
ZEB1 zinc finger E-box binding homeobox 1 0.161139
GDF9 growth differentiation factor 9 0.161139
MCAM melanoma cell adhesion molecule 0.160948
ADAM17 ADAM metallopeptidase domain 17 0.159838
LMAN1 lectin, mannose-binding, 1 0.159658
PMEL premelanosome protein 0.140192
MALT1 MALT1 paracaspase 0.138643
FGF4 fibroblast growth factor 4 0.138154
PEG10 paternally expressed 10 0.137002
BIRC3 baculoviral IAP repeat containing 3 0.136816
TSG101 tumor susceptibility 101 0.136642
C2 complement component 2 0.136418
MITF microphthalmia-associated transcription factor 0.136069
CDC6 cell division cycle 6 0.135152
BBC3 BCL2 binding component 3 0.135071
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 0.134225
MLANA melan-A 0.134083
DROSHA drosha, ribonuclease type III 0.133893
MYOG myogenin (myogenic factor 4) 0.13304
CTSD cathepsin D 0.132449
CD33 CD33 molecule 0.131925
MYOD1 myogenic differentiation 1 0.131829
CD86 CD86 molecule 0.12746
EZR ezrin 0.126059
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 0.118145
AMY2A amylase, alpha 2A (pancreatic) 0.117083
CDH3 cadherin 3, type 1, P-cadherin (placental) 0.117033
BMPR1A bone morphogenetic protein receptor, type IA 0.116983
KRT8 keratin 8, type II 0.116732
MCM2 minichromosome maintenance complex component 2 0.114967
S1PR1 sphingosine-1-phosphate receptor 1 0.112996
S100P S100 calcium binding protein P 0.112852
ARG1 arginase 1 0.11131
TYK2 tyrosine kinase 2 0.108071
PNLIP pancreatic lipase 0.107194
MCM7 minichromosome maintenance complex component 7 0.106784
EPHA2 EPH receptor A2 0.104744
WAPAL wings apart-like homolog (Drosophila) 0.104708
LYZ lysozyme 0.102566
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.1023
NDRG2 NDRG family member 2 0.102185
METAP2 methionyl aminopeptidase 2 0.102032
PDIA3 protein disulfide isomerase family A, member 3 0.102032
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 0.101534
RUNX3 runt-related transcription factor 3 0.101458
CGB chorionic gonadotropin, beta polypeptide 0.101109
CGB8 chorionic gonadotropin, beta polypeptide 8 0.10107
DICER1 dicer 1, ribonuclease type III 0.100913
ANXA1 annexin A1 0.100913
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.099329
CHPF chondroitin polymerizing factor 0.099209
ANXA2 annexin A2 0.097456
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 0.096577
XPC xeroderma pigmentosum, complementation group C 0.096577
CD9 CD9 molecule 0.096535
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy 0.096158
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase 0.096115
SOX4 SRY (sex determining region Y)-box 4 0.095901
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 0.095901
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.095132
BSG basigin (Ok blood group) 0.094919
MAGEC1 melanoma antigen family C1 0.093658
HDAC1 histone deacetylase 1 0.093571
GLUD1 glutamate dehydrogenase 1 0.093173
CALR calreticulin 0.092463
SELE selectin E 0.091701
NFE2L2 nuclear factor, erythroid 2-like 2 0.091159
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.091159
BTNL2 butyrophilin-like 2 0.090617
DLL4 delta-like 4 (Drosophila) 0.090387
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.089973
HNRNPK heterogeneous nuclear ribonucleoprotein K 0.089698