gallamine triethiodide-2059 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the gallamine triethiodide-2059 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADRBK1 adrenergic, beta, receptor kinase 1
AFF4 AF4/FMR2 family, member 4
AMBRA1 autophagy/beclin-1 regulator 1
ANKMY1 ankyrin repeat and MYND domain containing 1
ATP11A ATPase, class VI, type 11A
AURKA aurora kinase A
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide
BMP6 bone morphogenetic protein 6
BMPR1A bone morphogenetic protein receptor, type IA
CD68 CD68 molecule
CDC14A cell division cycle 14A
CDV3 CDV3 homolog (mouse)
CENPO centromere protein O
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7
CLCA1 chloride channel accessory 1
CLCN7 chloride channel, voltage-sensitive 7
CSF1R colony stimulating factor 1 receptor
DCAF11 DDB1 and CUL4 associated factor 11
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
EPS8L1 EPS8-like 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FBXO42 F-box protein 42
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FCF1 FCF1 rRNA-processing protein
FGFR2 fibroblast growth factor receptor 2
FOXO1 forkhead box O1
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GMPR guanosine monophosphate reductase
GSTTP1 glutathione S-transferase theta pseudogene 1
HABP4 hyaluronan binding protein 4
HAUS5 HAUS augmin-like complex, subunit 5
IGHA1 immunoglobulin heavy constant alpha 1
IGKV3-20 immunoglobulin kappa variable 3-20
IL11 interleukin 11
IL27RA interleukin 27 receptor, alpha
IQCE IQ motif containing E
JUN jun proto-oncogene
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KDM6B lysine (K)-specific demethylase 6B
KIAA0930 KIAA0930
KLF3 Kruppel-like factor 3 (basic)
KLHL36 kelch-like family member 36
KLK10 kallikrein-related peptidase 10
KYNU kynureninase
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae)
LYPD1 LY6/PLAUR domain containing 1
MBTD1 mbt domain containing 1
MC3R melanocortin 3 receptor
MCM4 minichromosome maintenance complex component 4
MEF2D myocyte enhancer factor 2D
MOCS1 molybdenum cofactor synthesis 1
MSH3 mutS homolog 3
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NKX3-2 NK3 homeobox 2
NNMT nicotinamide N-methyltransferase
NRG2 neuregulin 2
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OVGP1 oviductal glycoprotein 1, 120kDa
OXLD1 oxidoreductase-like domain containing 1
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PDAP1 PDGFA associated protein 1
PHF20L1 PHD finger protein 20-like 1
PHF3 PHD finger protein 3
PLD3 phospholipase D family, member 3
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
QSER1 glutamine and serine rich 1
RAB27B RAB27B, member RAS oncogene family
RAB6A RAB6A, member RAS oncogene family
RARA retinoic acid receptor, alpha
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RNF126P1 ring finger protein 126 pseudogene 1
RPL23AP32 ribosomal protein L23a pseudogene 32
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC41A3 solute carrier family 41, member 3
SLC48A1 solute carrier family 48 (heme transporter), member 1
SMAD5 SMAD family member 5
SPATS2L spermatogenesis associated, serine-rich 2-like
STC1 stanniocalcin 1
SUGP1 SURP and G patch domain containing 1
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
SYMPK symplekin
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TEX40 testis expressed 40
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TRPV1 transient receptor potential cation channel, subfamily V, member 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
UTRN utrophin
VPRBP Vpr (HIV-1) binding protein
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
VWA8 von Willebrand factor A domain containing 8
WDR1 WD repeat domain 1
WDR18 WD repeat domain 18
WT1 Wilms tumor 1
ZEB1 zinc finger E-box binding homeobox 1
ZNF222 zinc finger protein 222
ZNF614 zinc finger protein 614
ZNF778 zinc finger protein 778

decreased expression

Symbol Name
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
AEN apoptosis enhancing nuclease
AKR1C2 aldo-keto reductase family 1, member C2
AMT aminomethyltransferase
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
ARMC6 armadillo repeat containing 6
ATG2B autophagy related 2B
CAMTA2 calmodulin binding transcription activator 2
CBY1 chibby homolog 1 (Drosophila)
CCDC176 coiled-coil domain containing 176
CCS copper chaperone for superoxide dismutase
CENPQ centromere protein Q
CLASP1 cytoplasmic linker associated protein 1
CSNK1G3 casein kinase 1, gamma 3
DBF4B DBF4 zinc finger B
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DMTN dematin actin binding protein
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DUSP8 dual specificity phosphatase 8
ELAVL2 ELAV like neuron-specific RNA binding protein 2
ENO2 enolase 2 (gamma, neuronal)
ESM1 endothelial cell-specific molecule 1
FBRS fibrosin
FBXL15 F-box and leucine-rich repeat protein 15
FLCN folliculin
FOXC1 forkhead box C1
FPGS folylpolyglutamate synthase
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GPALPP1 GPALPP motifs containing 1
GPATCH2L G patch domain containing 2-like
GRPR gastrin-releasing peptide receptor
GTPBP2 GTP binding protein 2
HOXB9 homeobox B9
HSPA4L heat shock 70kDa protein 4-like
IFT22 intraflagellar transport 22
INSIG2 insulin induced gene 2
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KDM5C lysine (K)-specific demethylase 5C
KLC2 kinesin light chain 2
KRT8P12 keratin 8 pseudogene 12
LRRC8E leucine rich repeat containing 8 family, member E
LY6G5C lymphocyte antigen 6 complex, locus G5C
MAGEF1 melanoma antigen family F1
MFGE8 milk fat globule-EGF factor 8 protein
MFSD12 major facilitator superfamily domain containing 12
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MOXD1 monooxygenase, DBH-like 1
NDE1 nudE neurodevelopment protein 1
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OCLN occludin
PARP16 poly (ADP-ribose) polymerase family, member 16
PDZK1 PDZ domain containing 1
PECR peroxisomal trans-2-enoyl-CoA reductase
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLA2G15 phospholipase A2, group XV
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PLSCR4 phospholipid scramblase 4
PLXNA3 plexin A3
POMT2 protein-O-mannosyltransferase 2
PPDPF pancreatic progenitor cell differentiation and proliferation factor
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PRSS16 protease, serine, 16 (thymus)
PTPRR protein tyrosine phosphatase, receptor type, R
PYCRL pyrroline-5-carboxylate reductase-like
RAB17 RAB17, member RAS oncogene family
RUNX1-IT1 RUNX1 intronic transcript 1
SDC3 syndecan 3
SH2D2A SH2 domain containing 2A
SLC35F6 solute carrier family 35, member F6
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC4A3 solute carrier family 4 (anion exchanger), member 3
SNPH syntaphilin
SPEG SPEG complex locus
STK16 serine/threonine kinase 16
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
SYTL2 synaptotagmin-like 2
TFF2 trefoil factor 2
THAP7 THAP domain containing 7
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TPK1 thiamin pyrophosphokinase 1
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TSPYL2 TSPY-like 2
UNKL unkempt family zinc finger-like
USP21 ubiquitin specific peptidase 21
VEGFB vascular endothelial growth factor B
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae)
WDR91 WD repeat domain 91
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
XYLT2 xylosyltransferase II
ZFYVE16 zinc finger, FYVE domain containing 16
ZNF276 zinc finger protein 276