galantamine-4186 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the galantamine-4186 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOT11 acyl-CoA thioesterase 11
ACVR1B activin A receptor, type IB
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
ARHGAP28 Rho GTPase activating protein 28
ART1 ADP-ribosyltransferase 1
ASIC3 acid sensing (proton gated) ion channel 3
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
BBC3 BCL2 binding component 3
BLZF1 basic leucine zipper nuclear factor 1
BMP4 bone morphogenetic protein 4
C11ORF63 chromosome 11 open reading frame 63
C17ORF53 chromosome 17 open reading frame 53
C17ORF70 chromosome 17 open reading frame 70
CCDC186 coiled-coil domain containing 186
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
CLCN7 chloride channel, voltage-sensitive 7
COL16A1 collagen, type XVI, alpha 1
CYTH3 cytohesin 3
DICER1 dicer 1, ribonuclease type III
DLX4 distal-less homeobox 4
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DRD2 dopamine receptor D2
ELL elongation factor RNA polymerase II
EMID1 EMI domain containing 1
FAS Fas cell surface death receptor
FBXO22 F-box protein 22
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FGF22 fibroblast growth factor 22
FMO5 flavin containing monooxygenase 5
FRMD4B FERM domain containing 4B
FUBP1 far upstream element (FUSE) binding protein 1
FZD1 frizzled class receptor 1
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GLB1L galactosidase, beta 1-like
GLUL glutamate-ammonia ligase
HBS1L HBS1-like translational GTPase
HNF1A HNF1 homeobox A
HNMT histamine N-methyltransferase
HPS1 Hermansky-Pudlak syndrome 1
ICOSLG inducible T-cell co-stimulator ligand
IFFO1 intermediate filament family orphan 1
IFITM1 interferon induced transmembrane protein 1
IL22 interleukin 22
IRAK4 interleukin-1 receptor-associated kinase 4
IRF4 interferon regulatory factor 4
KCNIP1 Kv channel interacting protein 1
KLF12 Kruppel-like factor 12
LRP2 low density lipoprotein receptor-related protein 2
LRP4 low density lipoprotein receptor-related protein 4
LRRC15 leucine rich repeat containing 15
LYRM9 LYR motif containing 9
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
MOCS1 molybdenum cofactor synthesis 1
MR1 major histocompatibility complex, class I-related
MST1 macrophage stimulating 1
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NOD1 nucleotide-binding oligomerization domain containing 1
NRP2 neuropilin 2
NTNG1 netrin G1
PDLIM5 PDZ and LIM domain 5
PDZRN3 PDZ domain containing ring finger 3
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PPP4R4 protein phosphatase 4, regulatory subunit 4
PTPRU protein tyrosine phosphatase, receptor type, U
PVR poliovirus receptor
RAB26 RAB26, member RAS oncogene family
RAB31 RAB31, member RAS oncogene family
RANBP1 RAN binding protein 1
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RASA3 RAS p21 protein activator 3
RB1 retinoblastoma 1
REPS1 RALBP1 associated Eps domain containing 1
RET ret proto-oncogene
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SPEG SPEG complex locus
SPPL2B signal peptide peptidase like 2B
ST7L suppression of tumorigenicity 7 like
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TGFA transforming growth factor, alpha
TLN2 talin 2
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TTLL4 tubulin tyrosine ligase-like family member 4
UBR2 ubiquitin protein ligase E3 component n-recognin 2
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
WHSC1 Wolf-Hirschhorn syndrome candidate 1
WSB1 WD repeat and SOCS box containing 1
ZBTB1 zinc finger and BTB domain containing 1
ZBTB20 zinc finger and BTB domain containing 20
ZMYM5 zinc finger, MYM-type 5
ZNF778 zinc finger protein 778
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
ACE angiotensin I converting enzyme
ALG12 ALG12, alpha-1,6-mannosyltransferase
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARRB2 arrestin, beta 2
C14ORF105 chromosome 14 open reading frame 105
C22ORF46 chromosome 22 open reading frame 46
CASP5 caspase 5, apoptosis-related cysteine peptidase
CBX4 chromobox homolog 4
CBX8 chromobox homolog 8
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CLDN1 claudin 1
CLTCL1 clathrin, heavy chain-like 1
CNN1 calponin 1, basic, smooth muscle
CORO1A coronin, actin binding protein, 1A
CTSF cathepsin F
DSPP dentin sialophosphoprotein
EBF2 early B-cell factor 2
FAM53B family with sequence similarity 53, member B
FAM86C1 family with sequence similarity 86, member C1
FBXO2 F-box protein 2
FKBP5 FK506 binding protein 5
FLJ21369 uncharacterized protein FLJ21369
FRMPD1 FERM and PDZ domain containing 1
GIF gastric intrinsic factor (vitamin B synthesis)
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GTPBP2 GTP binding protein 2
HIST1H2AI histone cluster 1, H2ai
HIST1H2AK histone cluster 1, H2ak
HOXA6 homeobox A6
IL17RB interleukin 17 receptor B
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
ISYNA1 inositol-3-phosphate synthase 1
ITGB7 integrin, beta 7
KANSL3 KAT8 regulatory NSL complex subunit 3
KLF13 Kruppel-like factor 13
KRT20 keratin 20, type I
KRT86 keratin 86, type II
LIME1 Lck interacting transmembrane adaptor 1
LMO2 LIM domain only 2 (rhombotin-like 1)
LOC100287590 uncharacterized LOC100287590
LPAR4 lysophosphatidic acid receptor 4
MED15 mediator complex subunit 15
MFGE8 milk fat globule-EGF factor 8 protein
MGP matrix Gla protein
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MTSS1L metastasis suppressor 1-like
MYH15 myosin, heavy chain 15
MYO1F myosin IF
NACA2 nascent polypeptide-associated complex alpha subunit 2
NDRG4 NDRG family member 4
NTSR1 neurotensin receptor 1 (high affinity)
ODF2 outer dense fiber of sperm tails 2
PCDH12 protocadherin 12
PDE12 phosphodiesterase 12
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLBD1 phospholipase B domain containing 1
PLD3 phospholipase D family, member 3
PROX1 prospero homeobox 1
PRSS53 protease, serine, 53
RAB11B RAB11B, member RAS oncogene family
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
S1PR1 sphingosine-1-phosphate receptor 1
SAYSD1 SAYSVFN motif domain containing 1
SBNO2 strawberry notch homolog 2 (Drosophila)
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SERGEF secretion regulating guanine nucleotide exchange factor
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SNPH syntaphilin
SORBS3 sorbin and SH3 domain containing 3
SOX21 SRY (sex determining region Y)-box 21
SPATA1 spermatogenesis associated 1
SPIDR scaffolding protein involved in DNA repair
SPTBN2 spectrin, beta, non-erythrocytic 2
SRD5A3 steroid 5 alpha-reductase 3
STEAP4 STEAP family member 4
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TBC1D17 TBC1 domain family, member 17
TEAD3 TEA domain family member 3
TESPA1 thymocyte expressed, positive selection associated 1
TIGD6 tigger transposable element derived 6
TIMP4 TIMP metallopeptidase inhibitor 4
TLN1 talin 1
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TNS2 tensin 2
TTLL1 tubulin tyrosine ligase-like family member 1
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UGT8 UDP glycosyltransferase 8
VGF VGF nerve growth factor inducible
XAB2 XPA binding protein 2
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZNF358 zinc finger protein 358
ZNF528 zinc finger protein 528