gabexate-2937 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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199 genes differentially expressed following the gabexate-2937 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSL1 acyl-CoA synthetase long-chain family member 1
ADORA1 adenosine A1 receptor
ADORA3 adenosine A3 receptor
AHR aryl hydrocarbon receptor
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
AREG amphiregulin
ATP9A ATPase, class II, type 9A
BIN1 bridging integrator 1
CCL20 chemokine (C-C motif) ligand 20
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39)
CEP41 centrosomal protein 41kDa
CLCN4 chloride channel, voltage-sensitive 4
CLIP2 CAP-GLY domain containing linker protein 2
COL7A1 collagen, type VII, alpha 1
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
DMP1 dentin matrix acidic phosphoprotein 1
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DRICH1 aspartate-rich 1
DUSP1 dual specificity phosphatase 1
EFNA4 ephrin-A4
EFNB3 ephrin-B3
ERICH1 glutamate-rich 1
F3 coagulation factor III (thromboplastin, tissue factor)
FADS3 fatty acid desaturase 3
FBXO31 F-box protein 31
FKBP5 FK506 binding protein 5
FLT3 fms-related tyrosine kinase 3
FPR1 formyl peptide receptor 1
GAS8 growth arrest-specific 8
GATA6 GATA binding protein 6
GLP1R glucagon-like peptide 1 receptor
GLRX glutaredoxin (thioltransferase)
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GPR3 G protein-coupled receptor 3
GSDMB gasdermin B
GSN gelsolin
GSPT1 G1 to S phase transition 1
GTDC1 glycosyltransferase-like domain containing 1
HFE hemochromatosis
HOXC11 homeobox C11
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IL13RA1 interleukin 13 receptor, alpha 1
IL1R2 interleukin 1 receptor, type II
IL24 interleukin 24
INO80B INO80 complex subunit B
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
KIAA0513 KIAA0513
KLF13 Kruppel-like factor 13
KLF9 Kruppel-like factor 9
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LPPR1 lipid phosphate phosphatase-related protein type 1
LRRC48 leucine rich repeat containing 48
MARC1 mitochondrial amidoxime reducing component 1
METRN meteorin, glial cell differentiation regulator
MID2 midline 2
MINK1 misshapen-like kinase 1
NDE1 nudE neurodevelopment protein 1
NF2 neurofibromin 2 (merlin)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NLE1 notchless homolog 1 (Drosophila)
NRP1 neuropilin 1
OLAH oleoyl-ACP hydrolase
OLFML2A olfactomedin-like 2A
PER1 period circadian clock 1
PICALM phosphatidylinositol binding clathrin assembly protein
PLK3 polo-like kinase 3
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PTEN phosphatase and tensin homolog
RCAN1 regulator of calcineurin 1
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RHOB ras homolog family member B
RHOH ras homolog family member H
SDC2 syndecan 2
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SIGLEC7 sialic acid binding Ig-like lectin 7
SLAMF1 signaling lymphocytic activation molecule family member 1
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SULT4A1 sulfotransferase family 4A, member 1
TAOK2 TAO kinase 2
TBX6 T-box 6
TFDP3 transcription factor Dp family, member 3
THBS1 thrombospondin 1
THRA thyroid hormone receptor, alpha
TMEM176A transmembrane protein 176A
TMEM63A transmembrane protein 63A
TMOD1 tropomodulin 1
TPST1 tyrosylprotein sulfotransferase 1
TSC22D3 TSC22 domain family, member 3
TUBA4B tubulin, alpha 4b
VSIG4 V-set and immunoglobulin domain containing 4
WDR4 WD repeat domain 4
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZBTB16 zinc finger and BTB domain containing 16
ZFP36L2 ZFP36 ring finger protein-like 2
ZFPL1 zinc finger protein-like 1
ZNF639 zinc finger protein 639
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ADAMDEC1 ADAM-like, decysin 1
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ANAPC2 anaphase promoting complex subunit 2
ANXA3 annexin A3
BATF3 basic leucine zipper transcription factor, ATF-like 3
BPI bactericidal/permeability-increasing protein
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
C22ORF29 chromosome 22 open reading frame 29
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC57 coiled-coil domain containing 57
CCDC85C coiled-coil domain containing 85C
CCL2 chemokine (C-C motif) ligand 2
CD37 CD37 molecule
CD82 CD82 molecule
CD86 CD86 molecule
CHML choroideremia-like (Rab escort protein 2)
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
COQ4 coenzyme Q4
CTSL cathepsin L
CYSLTR1 cysteinyl leukotriene receptor 1
DEPTOR DEP domain containing MTOR-interacting protein
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DNAL4 dynein, axonemal, light chain 4
DNMBP dynamin binding protein
DPY19L1P1 DPY19L1 pseudogene 1
DVL1 dishevelled segment polarity protein 1
EGR2 early growth response 2
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAM127B family with sequence similarity 127, member B
FANCF Fanconi anemia, complementation group F
FGL1 fibrinogen-like 1
FOXO4 forkhead box O4
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GCH1 GTP cyclohydrolase 1
GID4 GID complex subunit 4
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPRASP1 G protein-coupled receptor associated sorting protein 1
HIST1H4D histone cluster 1, H4d
HIST1H4E histone cluster 1, H4e
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
ICAM1 intercellular adhesion molecule 1
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL11RA interleukin 11 receptor, alpha
IL1B interleukin 1, beta
IL4R interleukin 4 receptor
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
KDM7A lysine (K)-specific demethylase 7A
KIAA1107 KIAA1107
KRT8P12 keratin 8 pseudogene 12
LIMD2 LIM domain containing 2
MAGEB2 melanoma antigen family B2
MAGEF1 melanoma antigen family F1
MAK male germ cell-associated kinase
MCOLN1 mucolipin 1
MCPH1 microcephalin 1
MCTP2 multiple C2 domains, transmembrane 2
MECR mitochondrial trans-2-enoyl-CoA reductase
MVD mevalonate (diphospho) decarboxylase
PENK proenkephalin
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PIAS3 protein inhibitor of activated STAT, 3
PMFBP1 polyamine modulated factor 1 binding protein 1
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAB33A RAB33A, member RAS oncogene family
RBM47 RNA binding motif protein 47
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RND1 Rho family GTPase 1
RNF44 ring finger protein 44
SCAI suppressor of cancer cell invasion
SCUBE3 signal peptide, CUB domain, EGF-like 3
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SNAI1 snail family zinc finger 1
STAP1 signal transducing adaptor family member 1
STX1A syntaxin 1A (brain)
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TESK1 testis-specific kinase 1
THBS3 thrombospondin 3
TICAM1 toll-like receptor adaptor molecule 1
TMEM209 transmembrane protein 209
TSPYL2 TSPY-like 2
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UPK3A uroplakin 3A
WT1-AS WT1 antisense RNA
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
YPEL1 yippee-like 1 (Drosophila)
ZBTB22 zinc finger and BTB domain containing 22
ZDHHC18 zinc finger, DHHC-type containing 18
ZFYVE16 zinc finger, FYVE domain containing 16
ZKSCAN8 zinc finger with KRAB and SCAN domains 8
ZNF10 zinc finger protein 10
ZNF493 zinc finger protein 493
ZNRD1-AS1 ZNRD1 antisense RNA 1