g-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, where the pathway proceeds with activation or inhibition of a nucleotide cyclase activity and a subsequent change in the concentration of a cyclic nucleotide. (Gene Ontology, GO_0007187)
External Link http://amigo.geneontology.org/amigo/term/GO:0007187
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Genes

154 genes participating in the g-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ADCY1 adenylate cyclase 1 (brain)
ADCY2 adenylate cyclase 2 (brain)
ADCY3 adenylate cyclase 3
ADCY4 adenylate cyclase 4
ADCY5 adenylate cyclase 5
ADCY6 adenylate cyclase 6
ADCY7 adenylate cyclase 7
ADCY8 adenylate cyclase 8 (brain)
ADCY9 adenylate cyclase 9
ADM2 adrenomedullin 2
ADORA1 adenosine A1 receptor
ADORA2A adenosine A2a receptor
ADORA2B adenosine A2b receptor
ADRA1B adrenoceptor alpha 1B
ADRA1D adrenoceptor alpha 1D
ADRA2A adrenoceptor alpha 2A
ADRB1 adrenoceptor beta 1
ADRB2 adrenoceptor beta 2, surface
ADRB3 adrenoceptor beta 3
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR2 angiotensin II receptor, type 2
APLP1 amyloid beta (A4) precursor-like protein 1
AVPR2 arginine vasopressin receptor 2
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CALCA calcitonin-related polypeptide alpha
CALCR calcitonin receptor
CALCRL calcitonin receptor-like
CCL2 chemokine (C-C motif) ligand 2
CCR1 chemokine (C-C motif) receptor 1
CCR3 chemokine (C-C motif) receptor 3
CHRM1 cholinergic receptor, muscarinic 1
CHRM2 cholinergic receptor, muscarinic 2
CHRM3 cholinergic receptor, muscarinic 3
CHRM4 cholinergic receptor, muscarinic 4
CHRM5 cholinergic receptor, muscarinic 5
CNR1 cannabinoid receptor 1 (brain)
CNR2 cannabinoid receptor 2 (macrophage)
CORT cortistatin
CRHR2 corticotropin releasing hormone receptor 2
DRD1 dopamine receptor D1
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
DRD4 dopamine receptor D4
DRD5 dopamine receptor D5
FFAR3 free fatty acid receptor 3
FLNA filamin A, alpha
FPR1 formyl peptide receptor 1
FSHR follicle stimulating hormone receptor
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GALR1 galanin receptor 1
GALR2 galanin receptor 2
GALR3 galanin receptor 3
GCG glucagon
GCGR glucagon receptor
GHRH growth hormone releasing hormone
GHRHR growth hormone releasing hormone receptor
GLP2R glucagon-like peptide 2 receptor
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GNAS GNAS complex locus
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GNAT3 guanine nucleotide binding protein, alpha transducing 3
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GNG2 guanine nucleotide binding protein (G protein), gamma 2
GPR1 G protein-coupled receptor 1
GPR149 G protein-coupled receptor 149
GPR26 G protein-coupled receptor 26
GPR3 G protein-coupled receptor 3
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
GPR37L1 G protein-coupled receptor 37 like 1
GPR78 G protein-coupled receptor 78
GRIK3 glutamate receptor, ionotropic, kainate 3
GRK5 G protein-coupled receptor kinase 5
GRM2 glutamate receptor, metabotropic 2
GRM3 glutamate receptor, metabotropic 3
GRM4 glutamate receptor, metabotropic 4
GRM6 glutamate receptor, metabotropic 6
GRM7 glutamate receptor, metabotropic 7
GRM8 glutamate receptor, metabotropic 8
HRH2 histamine receptor H2
HRH3 histamine receptor H3
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
INSL3 insulin-like 3 (Leydig cell)
LHCGR luteinizing hormone/choriogonadotropin receptor
LPAR3 lysophosphatidic acid receptor 3
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MC3R melanocortin 3 receptor
MC4R melanocortin 4 receptor
MC5R melanocortin 5 receptor
MCHR1 melanin-concentrating hormone receptor 1
MTNR1A melatonin receptor 1A
MTNR1B melatonin receptor 1B
NPBWR1 neuropeptides B/W receptor 1
NPBWR2 neuropeptides B/W receptor 2
NPR3 natriuretic peptide receptor 3
NPY neuropeptide Y
NPY1R neuropeptide Y receptor Y1
NPY2R neuropeptide Y receptor Y2
OPRD1 opioid receptor, delta 1
OPRK1 opioid receptor, kappa 1
OPRL1 opiate receptor-like 1
OPRM1 opioid receptor, mu 1
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
P2RY12 purinergic receptor P2Y, G-protein coupled, 12
PDE4D phosphodiesterase 4D, cAMP-specific
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PTGDR2 prostaglandin D2 receptor 2
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
PTH parathyroid hormone
PTH1R parathyroid hormone 1 receptor
PTHLH parathyroid hormone-like hormone
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RGS1 regulator of G-protein signaling 1
RIC8A RIC8 guanine nucleotide exchange factor A
RXFP2 relaxin/insulin-like family peptide receptor 2
S1PR1 sphingosine-1-phosphate receptor 1
S1PR3 sphingosine-1-phosphate receptor 3
S1PR4 sphingosine-1-phosphate receptor 4
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SSTR1 somatostatin receptor 1
SSTR2 somatostatin receptor 2
SSTR3 somatostatin receptor 3
SSTR4 somatostatin receptor 4
SSTR5 somatostatin receptor 5
TBL3 transducin (beta)-like 3
TSHR thyroid stimulating hormone receptor
UCN2 urocortin 2
UCN3 urocortin 3
VIPR1 vasoactive intestinal peptide receptor 1
WASF2 WAS protein family, member 2
XCR1 chemokine (C motif) receptor 1