Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the fusidic acid-5353 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
AP2A2 | adaptor-related protein complex 2, alpha 2 subunit |
APC | adenomatous polyposis coli |
APOC1 | apolipoprotein C-I |
ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like |
ARID1A | AT rich interactive domain 1A (SWI-like) |
ARSB | arylsulfatase B |
ATG10 | autophagy related 10 |
ATM | ATM serine/threonine kinase |
ATP11A | ATPase, class VI, type 11A |
ATP7B | ATPase, Cu++ transporting, beta polypeptide |
ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
B4GALT7 | xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 |
BHLHE40 | basic helix-loop-helix family, member e40 |
CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit |
CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
CASKIN2 | CASK interacting protein 2 |
CCNO | cyclin O |
CD47 | CD47 molecule |
CDON | cell adhesion associated, oncogene regulated |
CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
CES2 | carboxylesterase 2 |
CLCF1 | cardiotrophin-like cytokine factor 1 |
CLMN | calmin (calponin-like, transmembrane) |
COL4A1 | collagen, type IV, alpha 1 |
CRY2 | cryptochrome circadian clock 2 |
CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
DOK1 | docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
EIF1 | eukaryotic translation initiation factor 1 |
EMC1 | ER membrane protein complex subunit 1 |
EML2 | echinoderm microtubule associated protein like 2 |
ERN2 | endoplasmic reticulum to nucleus signaling 2 |
F2R | coagulation factor II (thrombin) receptor |
FBXO9 | F-box protein 9 |
FGD1 | FYVE, RhoGEF and PH domain containing 1 |
GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
GATA2 | GATA binding protein 2 |
GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O |
HIST1H2AJ | histone cluster 1, H2aj |
HNMT | histamine N-methyltransferase |
HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 |
IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
INSR | insulin receptor |
ITFG2 | integrin alpha FG-GAP repeat containing 2 |
ITGB5 | integrin, beta 5 |
KCNG1 | potassium channel, voltage gated modifier subfamily G, member 1 |
LBX1 | ladybird homeobox 1 |
LMAN1 | lectin, mannose-binding, 1 |
LMNA | lamin A/C |
LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 |
LRRC20 | leucine rich repeat containing 20 |
LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
LTBP4 | latent transforming growth factor beta binding protein 4 |
MAPT | microtubule-associated protein tau |
MBTD1 | mbt domain containing 1 |
MMP25 | matrix metallopeptidase 25 |
MPPE1 | metallophosphoesterase 1 |
MRPS12 | mitochondrial ribosomal protein S12 |
MTRF1L | mitochondrial translational release factor 1-like |
NEK1 | NIMA-related kinase 1 |
NOS1 | nitric oxide synthase 1 (neuronal) |
NR2F6 | nuclear receptor subfamily 2, group F, member 6 |
P2RY4 | pyrimidinergic receptor P2Y, G-protein coupled, 4 |
PACS1 | phosphofurin acidic cluster sorting protein 1 |
PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
PAPPA | pregnancy-associated plasma protein A, pappalysin 1 |
PCDH1 | protocadherin 1 |
PCDHA6 | protocadherin alpha 6 |
PDCD2 | programmed cell death 2 |
PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
PFDN6 | prefoldin subunit 6 |
PIBF1 | progesterone immunomodulatory binding factor 1 |
PIGL | phosphatidylinositol glycan anchor biosynthesis, class L |
PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
PPIA | peptidylprolyl isomerase A (cyclophilin A) |
RBM34 | RNA binding motif protein 34 |
RGS10 | regulator of G-protein signaling 10 |
SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
SIN3B | SIN3 transcription regulator family member B |
SIVA1 | SIVA1, apoptosis-inducing factor |
SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
SOGA1 | suppressor of glucose, autophagy associated 1 |
SREBF2 | sterol regulatory element binding transcription factor 2 |
STX1A | syntaxin 1A (brain) |
SUN2 | Sad1 and UNC84 domain containing 2 |
SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) |
TCP11L1 | t-complex 11, testis-specific-like 1 |
TLDC1 | TBC/LysM-associated domain containing 1 |
TRIM2 | tripartite motif containing 2 |
TUBA3C | tubulin, alpha 3c |
TUSC2 | tumor suppressor candidate 2 |
USB1 | U6 snRNA biogenesis 1 |
VAC14 | Vac14 homolog (S. cerevisiae) |
VAV2 | vav 2 guanine nucleotide exchange factor |
ZER1 | zyg-11 related, cell cycle regulator |
ZNF34 | zinc finger protein 34 |
ZNF79 | zinc finger protein 79 |
Symbol | Name |
---|---|
ACADSB | acyl-CoA dehydrogenase, short/branched chain |
AFF4 | AF4/FMR2 family, member 4 |
ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A |
ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
ANXA2P3 | annexin A2 pseudogene 3 |
APOD | apolipoprotein D |
ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
BAGE | B melanoma antigen |
BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
BBS7 | Bardet-Biedl syndrome 7 |
BCL2L2 | BCL2-like 2 |
C14ORF132 | chromosome 14 open reading frame 132 |
C1ORF159 | chromosome 1 open reading frame 159 |
CAMTA1 | calmodulin binding transcription activator 1 |
CENPQ | centromere protein Q |
CHMP7 | charged multivesicular body protein 7 |
CRELD1 | cysteine-rich with EGF-like domains 1 |
CTSK | cathepsin K |
CUL9 | cullin 9 |
CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
DAP | death-associated protein |
DCPS | decapping enzyme, scavenger |
DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 |
DET1 | de-etiolated homolog 1 (Arabidopsis) |
DNAJC17 | DnaJ (Hsp40) homolog, subfamily C, member 17 |
EFNA3 | ephrin-A3 |
EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
EPHA2 | EPH receptor A2 |
FAM118A | family with sequence similarity 118, member A |
FAM57A | family with sequence similarity 57, member A |
FGD6 | FYVE, RhoGEF and PH domain containing 6 |
FSD1 | fibronectin type III and SPRY domain containing 1 |
FYCO1 | FYVE and coiled-coil domain containing 1 |
GBP2 | guanylate binding protein 2, interferon-inducible |
GCHFR | GTP cyclohydrolase I feedback regulator |
GLI3 | GLI family zinc finger 3 |
GLS2 | glutaminase 2 (liver, mitochondrial) |
GPR19 | G protein-coupled receptor 19 |
GPX2 | glutathione peroxidase 2 |
HMBOX1 | homeobox containing 1 |
HOXC10 | homeobox C10 |
HSPA2 | heat shock 70kDa protein 2 |
ICK | intestinal cell (MAK-like) kinase |
IFI6 | interferon, alpha-inducible protein 6 |
IREB2 | iron-responsive element binding protein 2 |
IRF6 | interferon regulatory factor 6 |
ISG15 | ISG15 ubiquitin-like modifier |
KIF18A | kinesin family member 18A |
KIF20A | kinesin family member 20A |
KRBOX4 | KRAB box domain containing 4 |
LMBR1L | limb development membrane protein 1-like |
LMNB1 | lamin B1 |
LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
MBIP | MAP3K12 binding inhibitory protein 1 |
MGAT1 | mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase |
MGC12488 | |
MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria |
MNS1 | meiosis-specific nuclear structural 1 |
MXD3 | MAX dimerization protein 3 |
NPLOC4 | nuclear protein localization 4 homolog (S. cerevisiae) |
OLFML3 | olfactomedin-like 3 |
PCSK7 | proprotein convertase subtilisin/kexin type 7 |
PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) |
PMP22 | peripheral myelin protein 22 |
POLR3F | polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa |
POU2F1 | POU class 2 homeobox 1 |
PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
RIBC2 | RIB43A domain with coiled-coils 2 |
RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
RWDD2A | RWD domain containing 2A |
SETD1B | SET domain containing 1B |
SFT2D2 | SFT2 domain containing 2 |
SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
SLC46A3 | solute carrier family 46, member 3 |
SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
STARD13 | StAR-related lipid transfer (START) domain containing 13 |
SYCP2 | synaptonemal complex protein 2 |
TCEAL1 | transcription elongation factor A (SII)-like 1 |
TCTN1 | tectonic family member 1 |
TDRD1 | tudor domain containing 1 |
THOP1 | thimet oligopeptidase 1 |
TMEM57 | transmembrane protein 57 |
TMPRSS3 | transmembrane protease, serine 3 |
TNRC6B | trinucleotide repeat containing 6B |
TP53BP1 | tumor protein p53 binding protein 1 |
TXLNG | taxilin gamma |
USP18 | ubiquitin specific peptidase 18 |
WDR19 | WD repeat domain 19 |
ZC3H3 | zinc finger CCCH-type containing 3 |
ZFP30 | ZFP30 zinc finger protein |
ZNF227 | zinc finger protein 227 |
ZNF274 | zinc finger protein 274 |
ZNF639 | zinc finger protein 639 |
ZNF675 | zinc finger protein 675 |