fusidic acid-2647 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the fusidic acid-2647 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
AKAP11 A kinase (PRKA) anchor protein 11
AKIP1 A kinase (PRKA) interacting protein 1
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
AMPD3 adenosine monophosphate deaminase 3
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
AR androgen receptor
ARHGAP26 Rho GTPase activating protein 26
ATF6B activating transcription factor 6 beta
ATXN7L3B ataxin 7-like 3B
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BCL2L2 BCL2-like 2
CCDC85B coiled-coil domain containing 85B
CHML choroideremia-like (Rab escort protein 2)
CLGN calmegin
COL13A1 collagen, type XIII, alpha 1
CORO7 coronin 7
CORT cortistatin
CPED1 cadherin-like and PC-esterase domain containing 1
CSRP2 cysteine and glycine-rich protein 2
CTNND2 catenin (cadherin-associated protein), delta 2
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DNAI2 dynein, axonemal, intermediate chain 2
DTNA dystrobrevin, alpha
DTX2 deltex 2, E3 ubiquitin ligase
DUSP2 dual specificity phosphatase 2
EIF1 eukaryotic translation initiation factor 1
ETNK2 ethanolamine kinase 2
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial
FGFR2 fibroblast growth factor receptor 2
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GLS glutaminase
GUSBP3 glucuronidase, beta pseudogene 3
HCFC2 host cell factor C2
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HR hair growth associated
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
IFT27 intraflagellar transport 27
IL6ST interleukin 6 signal transducer
INO80D INO80 complex subunit D
ITGB5 integrin, beta 5
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KCTD17 potassium channel tetramerization domain containing 17
KDM4C lysine (K)-specific demethylase 4C
KIAA1456 KIAA1456
KLHL22 kelch-like family member 22
KLK13 kallikrein-related peptidase 13
KRT19P2 keratin 19 pseudogene 2
LAMP1 lysosomal-associated membrane protein 1
LMNA lamin A/C
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAGEA3 melanoma antigen family A3
MAMLD1 mastermind-like domain containing 1
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MED16 mediator complex subunit 16
MFAP3L microfibrillar-associated protein 3-like
MOCS1 molybdenum cofactor synthesis 1
MPZ myelin protein zero
MTA2 metastasis associated 1 family, member 2
MTCP1 mature T-cell proliferation 1
MYF5 myogenic factor 5
N4BP3 NEDD4 binding protein 3
NFIB nuclear factor I/B
NPAT nuclear protein, ataxia-telangiectasia locus
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OCA2 oculocutaneous albinism II
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PHKA2 phosphorylase kinase, alpha 2 (liver)
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PTAFR platelet-activating factor receptor
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RARA retinoic acid receptor, alpha
RGS10 regulator of G-protein signaling 10
RPL23AP32 ribosomal protein L23a pseudogene 32
RPL35A ribosomal protein L35a
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SCAI suppressor of cancer cell invasion
SH3BP2 SH3-domain binding protein 2
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLPI secretory leukocyte peptidase inhibitor
SMAD5 SMAD family member 5
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SPON2 spondin 2, extracellular matrix protein
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYT12 synaptotagmin XII
TMEM45A transmembrane protein 45A
TRIL TLR4 interactor with leucine-rich repeats
TRIM33 tripartite motif containing 33
UBOX5 U-box domain containing 5
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
WDR61 WD repeat domain 61
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
YTHDC1 YTH domain containing 1
ZFHX4 zinc finger homeobox 4
ZNF304 zinc finger protein 304
ZNF696 zinc finger protein 696

decreased expression

Symbol Name
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ALPK1 alpha-kinase 1
AMT aminomethyltransferase
AP3M2 adaptor-related protein complex 3, mu 2 subunit
ARL15 ADP-ribosylation factor-like 15
ARRB1 arrestin, beta 1
BAHCC1 BAH domain and coiled-coil containing 1
BIRC7 baculoviral IAP repeat containing 7
BMP4 bone morphogenetic protein 4
C22ORF46 chromosome 22 open reading frame 46
C2ORF44 chromosome 2 open reading frame 44
CA11 carbonic anhydrase XI
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCNO cyclin O
CD1A CD1a molecule
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CGA glycoprotein hormones, alpha polypeptide
CHMP6 charged multivesicular body protein 6
CLCF1 cardiotrophin-like cytokine factor 1
CLDN15 claudin 15
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
DEAF1 DEAF1 transcription factor
DGAT1 diacylglycerol O-acyltransferase 1
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EGFL7 EGF-like-domain, multiple 7
EMID1 EMI domain containing 1
ERN2 endoplasmic reticulum to nucleus signaling 2
ERO1L ERO1-like (S. cerevisiae)
EXD3 exonuclease 3'-5' domain containing 3
EXO5 exonuclease 5
FAM204A family with sequence similarity 204, member A
FAM212B family with sequence similarity 212, member B
FBXO31 F-box protein 31
FKBP10 FK506 binding protein 10, 65 kDa
FSTL3 follistatin-like 3 (secreted glycoprotein)
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GEMIN8 gem (nuclear organelle) associated protein 8
GLI3 GLI family zinc finger 3
GRB7 growth factor receptor-bound protein 7
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BO histone cluster 1, H2bo
HYI hydroxypyruvate isomerase (putative)
INCENP inner centromere protein antigens 135/155kDa
IPO8 importin 8
JMJD4 jumonji domain containing 4
LAMB3 laminin, beta 3
LHX1 LIM homeobox 1
LHX6 LIM homeobox 6
LRRC37A2 leucine rich repeat containing 37, member A2
LRRC61 leucine rich repeat containing 61
MPI mannose phosphate isomerase
MYO19 myosin XIX
NDE1 nudE neurodevelopment protein 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NKX3-2 NK3 homeobox 2
NPM3 nucleophosmin/nucleoplasmin 3
OLFML3 olfactomedin-like 3
PCDHB3 protocadherin beta 3
PHEX phosphate regulating endopeptidase homolog, X-linked
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PPT2 palmitoyl-protein thioesterase 2
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
R3HCC1L R3H domain and coiled-coil containing 1-like
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RECQL4 RecQ protein-like 4
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNF121 ring finger protein 121
SCN1B sodium channel, voltage gated, type I beta subunit
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SH2D4A SH2 domain containing 4A
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SMG9 SMG9 nonsense mediated mRNA decay factor
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SNAI2 snail family zinc finger 2
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
TICAM1 toll-like receptor adaptor molecule 1
TMC7 transmembrane channel-like 7
TMEM180 transmembrane protein 180
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TPST2 tyrosylprotein sulfotransferase 2
TRABD TraB domain containing
TRIM21 tripartite motif containing 21
TUBG2 tubulin, gamma 2
UNC119 unc-119 homolog (C. elegans)
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF250 zinc finger protein 250
ZNF446 zinc finger protein 446
ZNF574 zinc finger protein 574
ZNF767P zinc finger family member 767, pseudogene