fusaric acid-4105 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the fusaric acid-4105 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACPP acid phosphatase, prostate
ACYP1 acylphosphatase 1, erythrocyte (common) type
ADAM20 ADAM metallopeptidase domain 20
ADAM22 ADAM metallopeptidase domain 22
ALOX5 arachidonate 5-lipoxygenase
ATP10B ATPase, class V, type 10B
ATXN8OS ATXN8 opposite strand (non-protein coding)
BIRC3 baculoviral IAP repeat containing 3
BMP1 bone morphogenetic protein 1
C10ORF12 chromosome 10 open reading frame 12
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CCL27 chemokine (C-C motif) ligand 27
CCL5 chemokine (C-C motif) ligand 5
CD1E CD1e molecule
CD58 CD58 molecule
CDK3 cyclin-dependent kinase 3
CEMP1 cementum protein 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLCA2 chloride channel accessory 2
CLUL1 clusterin-like 1 (retinal)
CRY2 cryptochrome circadian clock 2
DCN decorin
DCTN2 dynactin 2 (p50)
DOCK10 dedicator of cytokinesis 10
DYM dymeclin
EDNRB endothelin receptor type B
EFNA5 ephrin-A5
EFNB3 ephrin-B3
ELAVL3 ELAV like neuron-specific RNA binding protein 3
ELL2 elongation factor, RNA polymerase II, 2
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPN1 epsin 1
FABP7 fatty acid binding protein 7, brain
FLOT1 flotillin 1
FST follistatin
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
GIMAP6 GTPase, IMAP family member 6
GLRB glycine receptor, beta
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GPR143 G protein-coupled receptor 143
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GREB1L growth regulation by estrogen in breast cancer-like
GSK3A glycogen synthase kinase 3 alpha
GSPT1 G1 to S phase transition 1
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HFE hemochromatosis
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
ICA1 islet cell autoantigen 1, 69kDa
IL11 interleukin 11
IL2 interleukin 2
ING2 inhibitor of growth family, member 2
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KIAA0319L KIAA0319-like
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
KMT2A lysine (K)-specific methyltransferase 2A
KRT23 keratin 23, type I
LAMC2 laminin, gamma 2
LIMCH1 LIM and calponin homology domains 1
LPCAT4 lysophosphatidylcholine acyltransferase 4
LRRC37BP1 leucine rich repeat containing 37B pseudogene 1
MATN1 matrilin 1, cartilage matrix protein
MEFV Mediterranean fever
MEG3 maternally expressed 3 (non-protein coding)
MINK1 misshapen-like kinase 1
MTSS1L metastasis suppressor 1-like
MX1 MX dynamin-like GTPase 1
MYBPC3 myosin binding protein C, cardiac
NCOR2 nuclear receptor corepressor 2
NTN1 netrin 1
NUP88 nucleoporin 88kDa
OR52A1 olfactory receptor, family 52, subfamily A, member 1
PITX1 paired-like homeodomain 1
PLD2 phospholipase D2
PLEKHS1 pleckstrin homology domain containing, family S member 1
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RGS3 regulator of G-protein signaling 3
RUNX1 runt-related transcription factor 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SIX1 SIX homeobox 1
SLC16A4 solute carrier family 16, member 4
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SSPN sarcospan
SUGP1 SURP and G patch domain containing 1
TBC1D2 TBC1 domain family, member 2
TBRG4 transforming growth factor beta regulator 4
TEX14 testis expressed 14
TMEM206 transmembrane protein 206
TMOD1 tropomodulin 1
TMPRSS15 transmembrane protease, serine 15
TSPAN32 tetraspanin 32
UBXN1 UBX domain protein 1
ZBTB7A zinc finger and BTB domain containing 7A
ZNF493 zinc finger protein 493

decreased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABI3BP ABI family, member 3 (NESH) binding protein
ACSL4 acyl-CoA synthetase long-chain family member 4
ACVR2B activin A receptor, type IIB
ANXA2P3 annexin A2 pseudogene 3
ARAF A-Raf proto-oncogene, serine/threonine kinase
BCL7B B-cell CLL/lymphoma 7B
BMP4 bone morphogenetic protein 4
BPHL biphenyl hydrolase-like (serine hydrolase)
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
BTF3P12 basic transcription factor 3 pseudogene 12
C11ORF68 chromosome 11 open reading frame 68
CCNO cyclin O
CCNT1 cyclin T1
CD3D CD3d molecule, delta (CD3-TCR complex)
CES3 carboxylesterase 3
CFAP69 cilia and flagella associated protein 69
CHML choroideremia-like (Rab escort protein 2)
CLCN5 chloride channel, voltage-sensitive 5
CLDND1 claudin domain containing 1
CNR2 cannabinoid receptor 2 (macrophage)
CORO1A coronin, actin binding protein, 1A
CYB5R1 cytochrome b5 reductase 1
DGAT1 diacylglycerol O-acyltransferase 1
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DSCAM Down syndrome cell adhesion molecule
DYSF dysferlin
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EPHX2 epoxide hydrolase 2, cytoplasmic
FBXL7 F-box and leucine-rich repeat protein 7
FKBP5 FK506 binding protein 5
GADD45G growth arrest and DNA-damage-inducible, gamma
GBP2 guanylate binding protein 2, interferon-inducible
GPATCH2L G patch domain containing 2-like
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HDAC11 histone deacetylase 11
HIST1H1E histone cluster 1, H1e
HMOX1 heme oxygenase 1
IFT88 intraflagellar transport 88
INCENP inner centromere protein antigens 135/155kDa
IPO8 importin 8
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KLF3 Kruppel-like factor 3 (basic)
LOC730101 uncharacterized LOC730101
LPPR1 lipid phosphate phosphatase-related protein type 1
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LY6E lymphocyte antigen 6 complex, locus E
LYRM2 LYR motif containing 2
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MCOLN3 mucolipin 3
MDM4 MDM4, p53 regulator
MFSD11 major facilitator superfamily domain containing 11
MXD3 MAX dimerization protein 3
NABP2 nucleic acid binding protein 2
NKRF NFKB repressing factor
NRSN2 neurensin 2
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OSGIN1 oxidative stress induced growth inhibitor 1
PCDHGB5 protocadherin gamma subfamily B, 5
PDE8B phosphodiesterase 8B
PIH1D1 PIH1 domain containing 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
POLL polymerase (DNA directed), lambda
POPDC3 popeye domain containing 3
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4
PROL1 proline rich, lacrimal 1
REEP4 receptor accessory protein 4
RHOC ras homolog family member C
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
ROM1 retinal outer segment membrane protein 1
RPAP2 RNA polymerase II associated protein 2
RPL13P5 ribosomal protein L13 pseudogene 5
S100A4 S100 calcium binding protein A4
SAMD9 sterile alpha motif domain containing 9
SAV1 salvador family WW domain containing protein 1
SLC25A40 solute carrier family 25, member 40
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SND1-IT1 SND1 intronic transcript 1
SP1 Sp1 transcription factor
SSNA1 Sjogren syndrome nuclear autoantigen 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STON1 stonin 1
TAOK1 TAO kinase 1
TCTN2 tectonic family member 2
THYN1 thymocyte nuclear protein 1
TMX2 thioredoxin-related transmembrane protein 2
TRAF2 TNF receptor-associated factor 2
UBXN6 UBX domain protein 6
UPK3B uroplakin 3B
USB1 U6 snRNA biogenesis 1
VIM vimentin
VWA1 von Willebrand factor A domain containing 1
XDH xanthine dehydrogenase
ZMAT5 zinc finger, matrin-type 5
ZNF573 zinc finger protein 573