fusaric acid-3986 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the fusaric acid-3986 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ACOT11 acyl-CoA thioesterase 11
ACPP acid phosphatase, prostate
ACSM3 acyl-CoA synthetase medium-chain family member 3
ADAM23 ADAM metallopeptidase domain 23
ADCY9 adenylate cyclase 9
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADRBK1 adrenergic, beta, receptor kinase 1
AKAP5 A kinase (PRKA) anchor protein 5
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ALDOAP2 aldolase A, fructose-bisphosphate pseudogene 2
ANGEL2 angel homolog 2 (Drosophila)
BBC3 BCL2 binding component 3
BEND5 BEN domain containing 5
C11ORF63 chromosome 11 open reading frame 63
C22ORF29 chromosome 22 open reading frame 29
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCDC7 coiled-coil domain containing 7
CD82 CD82 molecule
CDY1 chromodomain protein, Y-linked, 1
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CEP295 centrosomal protein 295kDa
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CSRNP3 cysteine-serine-rich nuclear protein 3
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DMP1 dentin matrix acidic phosphoprotein 1
DST dystonin
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
EDA ectodysplasin A
EDIL3 EGF-like repeats and discoidin I-like domains 3
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EPHA5 EPH receptor A5
EPS8L1 EPS8-like 1
ETV1 ets variant 1
ETV6 ets variant 6
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GBP2 guanylate binding protein 2, interferon-inducible
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GRM2 glutamate receptor, metabotropic 2
GSTCD glutathione S-transferase, C-terminal domain containing
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HEMK1 HemK methyltransferase family member 1
HIPK3 homeodomain interacting protein kinase 3
HIRA histone cell cycle regulator
HIST1H4C histone cluster 1, H4c
HOXD10 homeobox D10
HPCAL4 hippocalcin like 4
ICOSLG inducible T-cell co-stimulator ligand
IFFO1 intermediate filament family orphan 1
IL1RN interleukin 1 receptor antagonist
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LAMC2 laminin, gamma 2
LTB4R leukotriene B4 receptor
LTBP4 latent transforming growth factor beta binding protein 4
MAP3K19 mitogen-activated protein kinase kinase kinase 19
MYO15A myosin XVA
MYO9B myosin IXB
OR2H2 olfactory receptor, family 2, subfamily H, member 2
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PBOV1 prostate and breast cancer overexpressed 1
PGAM2 phosphoglycerate mutase 2 (muscle)
PGM5 phosphoglucomutase 5
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
POFUT1 protein O-fucosyltransferase 1
PPARD peroxisome proliferator-activated receptor delta
PPP1R3D protein phosphatase 1, regulatory subunit 3D
PPP4R4 protein phosphatase 4, regulatory subunit 4
PQLC2 PQ loop repeat containing 2
PRKCI protein kinase C, iota
PRKCQ protein kinase C, theta
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
PTPRU protein tyrosine phosphatase, receptor type, U
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
RNGTT RNA guanylyltransferase and 5'-phosphatase
RPS4Y1 ribosomal protein S4, Y-linked 1
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RTCA RNA 3'-terminal phosphate cyclase
RUNX1 runt-related transcription factor 1
SIRT4 sirtuin 4
SLC44A1 solute carrier family 44 (choline transporter), member 1
SOX15 SRY (sex determining region Y)-box 15
STAT2 signal transducer and activator of transcription 2, 113kDa
STS steroid sulfatase (microsomal), isozyme S
TBL1Y transducin (beta)-like 1, Y-linked
THEMIS2 thymocyte selection associated family member 2
TLE2 transducin-like enhancer of split 2
TLE4 transducin-like enhancer of split 4
TMC6 transmembrane channel-like 6
TRADD TNFRSF1A-associated via death domain
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TSHB thyroid stimulating hormone, beta
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
WT1-AS WT1 antisense RNA
XYLB xylulokinase homolog (H. influenzae)
ZHX3 zinc fingers and homeoboxes 3
ZNF224 zinc finger protein 224
ZNF235 zinc finger protein 235

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ADGRE2 adhesion G protein-coupled receptor E2
ALOX12 arachidonate 12-lipoxygenase
ANXA10 annexin A10
APOC4 apolipoprotein C-IV
ARC activity-regulated cytoskeleton-associated protein
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
BAHCC1 BAH domain and coiled-coil containing 1
BSPRY B-box and SPRY domain containing
C5ORF42 chromosome 5 open reading frame 42
CA9 carbonic anhydrase IX
CAPN15 calpain 15
CCNO cyclin O
CHRDL1 chordin-like 1
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CNGB3 cyclic nucleotide gated channel beta 3
COG4 component of oligomeric golgi complex 4
CORT cortistatin
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DENND4A DENN/MADD domain containing 4A
DLK2 delta-like 2 homolog (Drosophila)
DSPP dentin sialophosphoprotein
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EFNB1 ephrin-B1
ERO1LB ERO1-like beta (S. cerevisiae)
EXOC6B exocyst complex component 6B
FAM110B family with sequence similarity 110, member B
FGF23 fibroblast growth factor 23
FRMPD1 FERM and PDZ domain containing 1
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GPC3 glypican 3
GPX2 glutathione peroxidase 2
GRM4 glutamate receptor, metabotropic 4
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
HDAC7 histone deacetylase 7
HIST1H2AJ histone cluster 1, H2aj
HIST2H2AA3 histone cluster 2, H2aa3
HSPA1L heat shock 70kDa protein 1-like
IL15RA interleukin 15 receptor, alpha
IRF2BP1 interferon regulatory factor 2 binding protein 1
JMJD4 jumonji domain containing 4
KCTD20 potassium channel tetramerization domain containing 20
KDM8 lysine (K)-specific demethylase 8
KIAA1456 KIAA1456
KIRREL kin of IRRE like (Drosophila)
LIME1 Lck interacting transmembrane adaptor 1
LOC100127972 uncharacterized LOC100127972
LPAR4 lysophosphatidic acid receptor 4
LRRC61 leucine rich repeat containing 61
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MED31 mediator complex subunit 31
MN1 meningioma (disrupted in balanced translocation) 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NLGN1 neuroligin 1
OCLN occludin
OLFML2A olfactomedin-like 2A
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OSBP2 oxysterol binding protein 2
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PARP3 poly (ADP-ribose) polymerase family, member 3
PICK1 protein interacting with PRKCA 1
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PPL periplakin
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRSS53 protease, serine, 53
PSKH1 protein serine kinase H1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PWAR5 Prader Willi/Angelman region RNA 5
RGCC regulator of cell cycle
RIMBP2 RIMS binding protein 2
SAYSD1 SAYSVFN motif domain containing 1
SCUBE3 signal peptide, CUB domain, EGF-like 3
SECISBP2 SECIS binding protein 2
SFT2D2 SFT2 domain containing 2
SIRT6 sirtuin 6
SLAMF7 SLAM family member 7
SLC16A6 solute carrier family 16, member 6
SLC46A3 solute carrier family 46, member 3
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
TBX19 T-box 19
TEX40 testis expressed 40
TINAGL1 tubulointerstitial nephritis antigen-like 1
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TNK1 tyrosine kinase, non-receptor, 1
TRIM9 tripartite motif containing 9
TTLL1 tubulin tyrosine ligase-like family member 1
TXK TXK tyrosine kinase
VGLL3 vestigial-like family member 3
WNT1 wingless-type MMTV integration site family, member 1
ZNF286A zinc finger protein 286A
ZNF37BP zinc finger protein 37B, pseudogene