fusaric acid-3245 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the fusaric acid-3245 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ADGRL1 adhesion G protein-coupled receptor L1
AHCYL1 adenosylhomocysteinase-like 1
ALPK1 alpha-kinase 1
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
BAHCC1 BAH domain and coiled-coil containing 1
BAIAP3 BAI1-associated protein 3
BCAT1 branched chain amino-acid transaminase 1, cytosolic
BHLHE40 basic helix-loop-helix family, member e40
BHLHE41 basic helix-loop-helix family, member e41
BTF3P11 basic transcription factor 3 pseudogene 11
C22ORF46 chromosome 22 open reading frame 46
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCDC132 coiled-coil domain containing 132
CCL19 chemokine (C-C motif) ligand 19
CD52 CD52 molecule
CDC14A cell division cycle 14A
CDH8 cadherin 8, type 2
CLSTN2 calsyntenin 2
CLTA clathrin, light chain A
COL6A1 collagen, type VI, alpha 1
COPZ2 coatomer protein complex, subunit zeta 2
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DFNB31 deafness, autosomal recessive 31
DMPK dystrophia myotonica-protein kinase
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EYA2 EYA transcriptional coactivator and phosphatase 2
F3 coagulation factor III (thromboplastin, tissue factor)
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
FBXO4 F-box protein 4
FGL2 fibrinogen-like 2
FLJ22184
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GLRA1 glycine receptor, alpha 1
GPER1 G protein-coupled estrogen receptor 1
HAB1 B1 for mucin
HCFC1 host cell factor C1
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
IMPG2 interphotoreceptor matrix proteoglycan 2
INHBE inhibin, beta E
INO80D INO80 complex subunit D
IRF2BP1 interferon regulatory factor 2 binding protein 1
JUN jun proto-oncogene
KCNK12 potassium channel, two pore domain subfamily K, member 12
KLHL25 kelch-like family member 25
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LPPR1 lipid phosphate phosphatase-related protein type 1
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LTBP4 latent transforming growth factor beta binding protein 4
MAP2K7 mitogen-activated protein kinase kinase 7
MAPK7 mitogen-activated protein kinase 7
MARK4 MAP/microtubule affinity-regulating kinase 4
MARS methionyl-tRNA synthetase
MOCS1 molybdenum cofactor synthesis 1
MTSS1L metastasis suppressor 1-like
MXD4 MAX dimerization protein 4
NANOG Nanog homeobox
NPC1 Niemann-Pick disease, type C1
NR2F1 nuclear receptor subfamily 2, group F, member 1
PARVB parvin, beta
PAX5 paired box 5
PDE8B phosphodiesterase 8B
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
PPP1R37 protein phosphatase 1, regulatory subunit 37
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RARA retinoic acid receptor, alpha
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
REM1 RAS (RAD and GEM)-like GTP-binding 1
RGS12 regulator of G-protein signaling 12
RNF126P1 ring finger protein 126 pseudogene 1
SAFB scaffold attachment factor B
SCAND2P SCAN domain containing 2 pseudogene
SCAPER S-phase cyclin A-associated protein in the ER
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SF3B3 splicing factor 3b, subunit 3, 130kDa
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SOAT2 sterol O-acyltransferase 2
SRF serum response factor (c-fos serum response element-binding transcription factor)
STON1 stonin 1
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)
SYMPK symplekin
SYT12 synaptotagmin XII
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
TAS2R7 taste receptor, type 2, member 7
TLDC1 TBC/LysM-associated domain containing 1
TMEM45A transmembrane protein 45A
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TRIB2 tribbles pseudokinase 2
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
VCL vinculin
VLDLR very low density lipoprotein receptor
VPRBP Vpr (HIV-1) binding protein
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
YTHDC2 YTH domain containing 2
ZFPL1 zinc finger protein-like 1
ZNF34 zinc finger protein 34

decreased expression

Symbol Name
ACSF2 acyl-CoA synthetase family member 2
ALDOC aldolase C, fructose-bisphosphate
ANKFY1 ankyrin repeat and FYVE domain containing 1
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARRB1 arrestin, beta 1
BPGM 2,3-bisphosphoglycerate mutase
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BSG basigin (Ok blood group)
C11ORF80 chromosome 11 open reading frame 80
C17ORF80 chromosome 17 open reading frame 80
C1ORF56 chromosome 1 open reading frame 56
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CCDC51 coiled-coil domain containing 51
CCNL2 cyclin L2
CEP85 centrosomal protein 85kDa
CHMP6 charged multivesicular body protein 6
CNKSR1 connector enhancer of kinase suppressor of Ras 1
COMMD10 COMM domain containing 10
CRIP2 cysteine-rich protein 2
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DDA1 DET1 and DDB1 associated 1
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
EDC3 enhancer of mRNA decapping 3
EFNA3 ephrin-A3
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
EXOC5 exocyst complex component 5
FAM188A family with sequence similarity 188, member A
FAM63A family with sequence similarity 63, member A
FGGY FGGY carbohydrate kinase domain containing
FNTB farnesyltransferase, CAAX box, beta
FUZ fuzzy planar cell polarity protein
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GDAP1 ganglioside induced differentiation associated protein 1
GDE1 glycerophosphodiester phosphodiesterase 1
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPR19 G protein-coupled receptor 19
GPX2 glutathione peroxidase 2
GTF2I general transcription factor IIi
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa
GTPBP2 GTP binding protein 2
GUF1 GUF1 GTPase homolog (S. cerevisiae)
IKZF5 IKAROS family zinc finger 5 (Pegasus)
INPP5K inositol polyphosphate-5-phosphatase K
IREB2 iron-responsive element binding protein 2
KCTD20 potassium channel tetramerization domain containing 20
KLHL21 kelch-like family member 21
KLK5 kallikrein-related peptidase 5
LINC00339 long intergenic non-protein coding RNA 339
LINS lines homolog (Drosophila)
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAGEF1 melanoma antigen family F1
MBTPS2 membrane-bound transcription factor peptidase, site 2
MCAT malonyl CoA:ACP acyltransferase (mitochondrial)
MCRS1 microspherule protein 1
METTL16 methyltransferase like 16
MPDU1 mannose-P-dolichol utilization defect 1
NR1D2 nuclear receptor subfamily 1, group D, member 2
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
PARD6A par-6 family cell polarity regulator alpha
PCOLCE2 procollagen C-endopeptidase enhancer 2
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PLA2G10 phospholipase A2, group X
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PPAP2C phosphatidic acid phosphatase type 2C
PSENEN presenilin enhancer gamma secretase subunit
PTBP2 polypyrimidine tract binding protein 2
R3HCC1L R3H domain and coiled-coil containing 1-like
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
SCYL2 SCY1-like 2 (S. cerevisiae)
SETD8 SET domain containing (lysine methyltransferase) 8
SH3GLB2 SH3-domain GRB2-like endophilin B2
SND1-IT1 SND1 intronic transcript 1
SPAG4 sperm associated antigen 4
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
TAGLN transgelin
TECR trans-2,3-enoyl-CoA reductase
TMEM177 transmembrane protein 177
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TPRA1 transmembrane protein, adipocyte asscociated 1
TRAF2 TNF receptor-associated factor 2
TRAPPC11 trafficking protein particle complex 11
TSPAN1 tetraspanin 1
TSTA3 tissue specific transplantation antigen P35B
UNC119 unc-119 homolog (C. elegans)
USB1 U6 snRNA biogenesis 1
WDR46 WD repeat domain 46
YIPF5 Yip1 domain family, member 5
ZFYVE21 zinc finger, FYVE domain containing 21
ZMAT5 zinc finger, matrin-type 5
ZNF211 zinc finger protein 211
ZNF250 zinc finger protein 250
ZNF510 zinc finger protein 510
ZNF665 zinc finger protein 665
ZW10 zw10 kinetochore protein