fusaric acid-1308 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the fusaric acid-1308 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD6 abhydrolase domain containing 6
ANKRD12 ankyrin repeat domain 12
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
AQP1 aquaporin 1 (Colton blood group)
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
AZU1 azurocidin 1
BIN1 bridging integrator 1
C21ORF2 chromosome 21 open reading frame 2
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CAPN2 calpain 2, (m/II) large subunit
CCDC9 coiled-coil domain containing 9
CD58 CD58 molecule
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa
CTSH cathepsin H
CYB561 cytochrome b561
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
EDC3 enhancer of mRNA decapping 3
EIF5B eukaryotic translation initiation factor 5B
ELL2 elongation factor, RNA polymerase II, 2
EMILIN2 elastin microfibril interfacer 2
EPHB2 EPH receptor B2
ERAP2 endoplasmic reticulum aminopeptidase 2
EXT1 exostosin glycosyltransferase 1
FAM149B1 family with sequence similarity 149, member B1
FAM188A family with sequence similarity 188, member A
FASTK Fas-activated serine/threonine kinase
FNTB farnesyltransferase, CAAX box, beta
GNG7 guanine nucleotide binding protein (G protein), gamma 7
HDAC7 histone deacetylase 7
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IGL immunoglobulin lambda locus
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
KRT86 keratin 86, type II
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LOXL3 lysyl oxidase-like 3
LRRC23 leucine rich repeat containing 23
MAP2K7 mitogen-activated protein kinase kinase 7
MAP4 microtubule-associated protein 4
METTL7A methyltransferase like 7A
MKL2 MKL/myocardin-like 2
MRPS12 mitochondrial ribosomal protein S12
MTUS1 microtubule associated tumor suppressor 1
MX1 MX dynamin-like GTPase 1
NDE1 nudE neurodevelopment protein 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NLK nemo-like kinase
NLRP1 NLR family, pyrin domain containing 1
NOP16 NOP16 nucleolar protein
NT5DC3 5'-nucleotidase domain containing 3
OGFR opioid growth factor receptor
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PEX11A peroxisomal biogenesis factor 11 alpha
PGPEP1 pyroglutamyl-peptidase I
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLA2G15 phospholipase A2, group XV
PLCB4 phospholipase C, beta 4
PLCD1 phospholipase C, delta 1
PLCG1 phospholipase C, gamma 1
PLK3 polo-like kinase 3
PLK4 polo-like kinase 4
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
PTGES2 prostaglandin E synthase 2
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPRA protein tyrosine phosphatase, receptor type, A
PYGB phosphorylase, glycogen; brain
RNMT RNA (guanine-7-) methyltransferase
RPL23AP32 ribosomal protein L23a pseudogene 32
S1PR4 sphingosine-1-phosphate receptor 4
SAPCD1 suppressor APC domain containing 1
SDC2 syndecan 2
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SIGLEC7 sialic acid binding Ig-like lectin 7
SLC12A8 solute carrier family 12, member 8
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SPATA5L1 spermatogenesis associated 5-like 1
STAP1 signal transducing adaptor family member 1
STXBP6 syntaxin binding protein 6 (amisyn)
TMC7 transmembrane channel-like 7
TMEM120B transmembrane protein 120B
TMEM254 transmembrane protein 254
TRIP11 thyroid hormone receptor interactor 11
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WASL Wiskott-Aldrich syndrome-like
WDR62 WD repeat domain 62
WDTC1 WD and tetratricopeptide repeats 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
YIPF4 Yip1 domain family, member 4
YY2 YY2 transcription factor
ZFHX4 zinc finger homeobox 4
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
AMT aminomethyltransferase
ARMC6 armadillo repeat containing 6
ASB6 ankyrin repeat and SOCS box containing 6
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BTBD18 BTB (POZ) domain containing 18
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
C6ORF47 chromosome 6 open reading frame 47
C9ORF114 chromosome 9 open reading frame 114
C9ORF40 chromosome 9 open reading frame 40
CBY1 chibby homolog 1 (Drosophila)
CCDC69 coiled-coil domain containing 69
CCRL2 chemokine (C-C motif) receptor-like 2
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CECR1 cat eye syndrome chromosome region, candidate 1
CHST10 carbohydrate sulfotransferase 10
COA7 cytochrome c oxidase assembly factor 7 (putative)
COPS7B COP9 signalosome subunit 7B
COQ3 coenzyme Q3 methyltransferase
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae)
CRYZ crystallin, zeta (quinone reductase)
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CXORF56 chromosome X open reading frame 56
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DHDDS dehydrodolichyl diphosphate synthase
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
ECI2 enoyl-CoA delta isomerase 2
ELP6 elongator acetyltransferase complex subunit 6
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
EXOC5 exocyst complex component 5
FHIT fragile histidine triad
FYCO1 FYVE and coiled-coil domain containing 1
GSTCD glutathione S-transferase, C-terminal domain containing
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
GTF2I general transcription factor IIi
HIST1H2BH histone cluster 1, H2bh
HMGB3P1 high mobility group box 3 pseudogene 1
INF2 inverted formin, FH2 and WH2 domain containing
ITFG1 integrin alpha FG-GAP repeat containing 1
KDM7A lysine (K)-specific demethylase 7A
KLHDC4 kelch domain containing 4
KLHL21 kelch-like family member 21
KLHL26 kelch-like family member 26
LAMP5 lysosomal-associated membrane protein family, member 5
LRRK1 leucine-rich repeat kinase 1
LYPLA2P1 lysophospholipase II pseudogene 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAGEB2 melanoma antigen family B2
MED9 mediator complex subunit 9
METTL1 methyltransferase like 1
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
MMP2 matrix metallopeptidase 2
MOGS mannosyl-oligosaccharide glucosidase
MON1B MON1 secretory trafficking family member B
NOL6 nucleolar protein 6 (RNA-associated)
NPFFR1 neuropeptide FF receptor 1
NPIPB3 nuclear pore complex interacting protein family, member B3
NRBP1 nuclear receptor binding protein 1
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PDLIM2 PDZ and LIM domain 2 (mystique)
PPDPF pancreatic progenitor cell differentiation and proliferation factor
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
QPCT glutaminyl-peptide cyclotransferase
RAB23 RAB23, member RAS oncogene family
RHOC ras homolog family member C
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
SCO2 SCO2 cytochrome c oxidase assembly protein
SCYL2 SCY1-like 2 (S. cerevisiae)
SIDT1 SID1 transmembrane family, member 1
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SMA4 glucuronidase, beta pseudogene
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBC1D4 TBC1 domain family, member 4
TBX19 T-box 19
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TCTN2 tectonic family member 2
TFPT TCF3 (E2A) fusion partner (in childhood Leukemia)
TIMM10 translocase of inner mitochondrial membrane 10 homolog (yeast)
TLR4 toll-like receptor 4
TMEM242 transmembrane protein 242
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIM25 tripartite motif containing 25
TXNL4B thioredoxin-like 4B
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
VASH1 vasohibin 1
ZDHHC11 zinc finger, DHHC-type containing 11
ZDHHC18 zinc finger, DHHC-type containing 18
ZNF250 zinc finger protein 250
ZNF32 zinc finger protein 32
ZNF354A zinc finger protein 354A
ZNF408 zinc finger protein 408
ZNF623 zinc finger protein 623
ZNF675 zinc finger protein 675