fursultiamine-7349 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the fursultiamine-7349 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAP1 ArfGAP with dual PH domains 1
ARC activity-regulated cytoskeleton-associated protein
ARNT aryl hydrocarbon receptor nuclear translocator
ATAT1 alpha tubulin acetyltransferase 1
ATF7IP activating transcription factor 7 interacting protein
ATRN attractin
CACFD1 calcium channel flower domain containing 1
CCDC9 coiled-coil domain containing 9
CCR2 chemokine (C-C motif) receptor 2
CD52 CD52 molecule
CFLAR CASP8 and FADD-like apoptosis regulator
CLCN5 chloride channel, voltage-sensitive 5
CTBP2 C-terminal binding protein 2
CTNS cystinosin, lysosomal cystine transporter
CYR61 cysteine-rich, angiogenic inducer, 61
DCAF15 DDB1 and CUL4 associated factor 15
DMPK dystrophia myotonica-protein kinase
DOK4 docking protein 4
DSCAM Down syndrome cell adhesion molecule
DTNA dystrobrevin, alpha
EFNA3 ephrin-A3
ELOVL5 ELOVL fatty acid elongase 5
EML3 echinoderm microtubule associated protein like 3
EPOR erythropoietin receptor
ERAP1 endoplasmic reticulum aminopeptidase 1
EXO5 exonuclease 5
FAM65A family with sequence similarity 65, member A
FHL1 four and a half LIM domains 1
FSCN1 fascin actin-bundling protein 1
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GBP1 guanylate binding protein 1, interferon-inducible
GMPR guanosine monophosphate reductase
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GON4L gon-4-like (C. elegans)
GOSR1 golgi SNAP receptor complex member 1
GPER1 G protein-coupled estrogen receptor 1
GYG2 glycogenin 2
HFE hemochromatosis
IL2 interleukin 2
IL22 interleukin 22
KCTD7 potassium channel tetramerization domain containing 7
KIAA0930 KIAA0930
KRIT1 KRIT1, ankyrin repeat containing
LAMP1 lysosomal-associated membrane protein 1
LAX1 lymphocyte transmembrane adaptor 1
LPIN2 lipin 2
LRP5L low density lipoprotein receptor-related protein 5-like
LRRC23 leucine rich repeat containing 23
LYST lysosomal trafficking regulator
MALT1 MALT1 paracaspase
MAP2K5 mitogen-activated protein kinase kinase 5
MED16 mediator complex subunit 16
MICALL1 MICAL-like 1
NAIP NLR family, apoptosis inhibitory protein
NCBP1 nuclear cap binding protein subunit 1, 80kDa
NF1 neurofibromin 1
NR6A1 nuclear receptor subfamily 6, group A, member 1
PADI1 peptidyl arginine deiminase, type I
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PER1 period circadian clock 1
PHC1 polyhomeotic homolog 1 (Drosophila)
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PRF1 perforin 1 (pore forming protein)
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1
RBM34 RNA binding motif protein 34
RECQL5 RecQ protein-like 5
SAP30 Sin3A-associated protein, 30kDa
SBF1 SET binding factor 1
SCUBE2 signal peptide, CUB domain, EGF-like 2
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SIK3 SIK family kinase 3
SIPA1 signal-induced proliferation-associated 1
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
SPRR1A small proline-rich protein 1A
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3
SPTAN1 spectrin, alpha, non-erythrocytic 1
SRPX sushi-repeat containing protein, X-linked
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STMN1 stathmin 1
SYCE1L synaptonemal complex central element protein 1-like
TADA2A transcriptional adaptor 2A
TDRD3 tudor domain containing 3
TLDC1 TBC/LysM-associated domain containing 1
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TLR5 toll-like receptor 5
TMEM212 transmembrane protein 212
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
TOP3A topoisomerase (DNA) III alpha
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TSC22D4 TSC22 domain family, member 4
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WAS Wiskott-Aldrich syndrome
ZFP36L1 ZFP36 ring finger protein-like 1
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF34 zinc finger protein 34
ZNF783 zinc finger family member 783

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ADAP2 ArfGAP with dual PH domains 2
AFF4 AF4/FMR2 family, member 4
AHDC1 AT hook, DNA binding motif, containing 1
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
ALG12 ALG12, alpha-1,6-mannosyltransferase
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARHGAP11A Rho GTPase activating protein 11A
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BPGM 2,3-bisphosphoglycerate mutase
BPHL biphenyl hydrolase-like (serine hydrolase)
C14ORF93 chromosome 14 open reading frame 93
C21ORF91 chromosome 21 open reading frame 91
CDON cell adhesion associated, oncogene regulated
CEP97 centrosomal protein 97kDa
CHML choroideremia-like (Rab escort protein 2)
CPPED1 calcineurin-like phosphoesterase domain containing 1
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DRD1 dopamine receptor D1
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
ERCC4 excision repair cross-complementation group 4
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ERN2 endoplasmic reticulum to nucleus signaling 2
FBXO31 F-box protein 31
FLJ11710 uncharacterized protein FLJ11710
GLS2 glutaminase 2 (liver, mitochondrial)
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPR27 G protein-coupled receptor 27
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HIST1H4F histone cluster 1, H4f
HLA-J major histocompatibility complex, class I, J (pseudogene)
HOXC10 homeobox C10
IFI6 interferon, alpha-inducible protein 6
INCENP inner centromere protein antigens 135/155kDa
INSIG2 insulin induced gene 2
IPO8 importin 8
IRAK4 interleukin-1 receptor-associated kinase 4
KDM8 lysine (K)-specific demethylase 8
KLF3 Kruppel-like factor 3 (basic)
KLF7 Kruppel-like factor 7 (ubiquitous)
KLHL25 kelch-like family member 25
KRT24 keratin 24, type I
LIG4 ligase IV, DNA, ATP-dependent
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAP1S microtubule-associated protein 1S
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MON1B MON1 secretory trafficking family member B
NRSN2 neurensin 2
OLFML2A olfactomedin-like 2A
ONECUT2 one cut homeobox 2
PARP12 poly (ADP-ribose) polymerase family, member 12
PCDHB13 protocadherin beta 13
PCDHB3 protocadherin beta 3
PGBD5 piggyBac transposable element derived 5
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PRKD3 protein kinase D3
PROCR protein C receptor, endothelial
PTPRE protein tyrosine phosphatase, receptor type, E
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB3A RAB3A, member RAS oncogene family
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RETSAT retinol saturase (all-trans-retinol 13,14-reductase)
RPGR retinitis pigmentosa GTPase regulator
SAV1 salvador family WW domain containing protein 1
SCHIP1 schwannomin interacting protein 1
SCML2 sex comb on midleg-like 2 (Drosophila)
SCN1B sodium channel, voltage gated, type I beta subunit
SLC12A9 solute carrier family 12, member 9
SLC46A3 solute carrier family 46, member 3
SND1-IT1 SND1 intronic transcript 1
SP1 Sp1 transcription factor
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TBX19 T-box 19
TDRD1 tudor domain containing 1
TIGD6 tigger transposable element derived 6
TMEM183A transmembrane protein 183A
TRIM25 tripartite motif containing 25
TUBA3C tubulin, alpha 3c
UBQLN4 ubiquilin 4
USB1 U6 snRNA biogenesis 1
VGF VGF nerve growth factor inducible
WDR76 WD repeat domain 76
ZBTB39 zinc finger and BTB domain containing 39
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF134 zinc finger protein 134
ZNF205 zinc finger protein 205
ZNF365 zinc finger protein 365
ZSCAN31 zinc finger and SCAN domain containing 31