fumarate reductase complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A membrane-bound flavoenzyme complex consisting of four subunits, A, B, C, and D. A and B comprise the membrane-extrinsic catalytic domain and C (InterPro:IPR003510; InterPro:IPR004224) and D (InterPro:IPR003418) link the catalytic centers to the electron-transport chain. This family consists of the 13 kDa hydrophobic subunit D. This component may be required to anchor the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. Fumarate reductase couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, in a reaction opposite to that catalyzed by the related complex II of the respiratory chain (succinate dehydrogenase-(ubiquinone)). (Gene Ontology, GO_0045283)
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Genes

15 proteins co-occuring with the fumarate reductase complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 1.55878
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 1.45703
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 1.31897
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa 1.29424
SDHAF1 succinate dehydrogenase complex assembly factor 1 1.27717
SDHAF2 succinate dehydrogenase complex assembly factor 2 0.863988
GALK1 galactokinase 1 0.76726
MPV17 MpV17 mitochondrial inner membrane protein 0.65388
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 0.64958
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 0.620104
MMD monocyte to macrophage differentiation-associated 0.552664
CARTPT CART prepropeptide 0.502693
HTT huntingtin 0.299569
ESR2 estrogen receptor 2 (ER beta) 0.284401
CS citrate synthase 0.173273